Job title: HEVA (HEOR) Business Partner
- Location: Cambridge, MA or Morristown, NJ (hybrid with 3 days a week on-site requirement)
Main ResponsibilitiesThis role will lead Health Economic and Outcomes Research activities for AYVAKIT® in Systemic Mastocytosis and emerging pipeline assets within the Global Rare HEVA team.
- Lead the development and execution of asset-level HEOR strategies within the global HEVA framework for AYVAKIT® (avapritinib) in Systemic Mastocytosis (advanced SM and indolent SM) and assigned emerging pipeline assets, translating Target Value Propositions and access strategies into evidence hypotheses, requirements, and generation plans that address payer/provider/health system unmet needs in rare mast cell disease; operate with medium independence for strategic work and high independence for tactical execution.
- Design and execute HEOR research - including economic modeling, database analysis, observational research, Clinical Outcomes Assessment (COA) development and validation, systematic literature review, evidence synthesis, and value dossier development - and operationalize and execute evidence generation priorities for assigned Systemic Mastocytosis indications and emerging assets, incorporating them into broader Sanofi planning documents such as the Integrated Evidence Generation Plan (IEGP).
- Operate as part of a multi-functional global brand and development team responsible for designing clinical research programs to meet the evidentiary standards of regulators, HTA organizations, reimbursement authorities, and third-party payers; provide trial design recommendations; serve as a subject matter expert providing input to commercial, medical, market access, and strategy development teams; and align closely with the US HEVA team to ensure the global evidence strategy reflects US access and payer needs.
- Develop collaborative research relationships with payers and other decision-makers to inform value demonstration strategies for AYVAKIT® and pipeline assets, leveraging payer interactions to identify strategies that improve the impact of research and build advocates for data; support interactions with global HTA bodies and reimbursement authorities; and engage with key opinion leaders and external research partners to advance HEVA science in Systemic Mastocytosis.
- Contribute to scientific publications and presentations in peer-reviewed journals and at major congresses; distill complex HEOR findings into clear, audience-appropriate communications for internal and external stakeholders; maintain compliance with all relevant internal SOPs and external laws and regulations; and mentor junior colleagues on a case-by-case basis, sharing HEOR expertise and supporting their professional development.
About You- Advanced degree (PhD, MD, MS, MPH, or PharmD) in a scientific discipline
- 5 years of experience in health economics, outcomes research, or a related field
- Global product launch experience; understanding of payer evidence requirements and value demonstration in a competitive market
- Demonstrated experience applying various HEOR methods to specific research projects and supporting global launches
- Proficiency in principles of evidence-based medicine and clinical research methodology, economic modeling, and COAs
- Experience in translating Target Value Propositions and access strategies into evidence hypotheses, requirements, and generation plans
- Established track record of scientific and/or methods publications in peer-reviewed journals
- Knowledge of global HTA processes and guidelines; experience with HTA submissions preferred
- Strong ability to partner with colleagues from non-HEOR functional areas
- Compliance with all relevant internal SOPs and external laws and regulations
Technical Skills:
- Demonstrated understanding of disease physiopathology, drug mechanism of action, health economic modeling, clinical development principles, epidemiology, biostatistics, statistical programming, COA development, systematic literature reviews, and network meta-analyses
- Working proficiency with HEOR-relevant digital tools and data platforms; ability to apply digital solutions to enhance research efficiency
Soft Skills:
- Strong communication skills, both verbal and written, including presentation skills; significant experience making presentations to senior management strongly desired
- Understanding of the legal and regulatory environment of the pharmaceutical industry; demonstrated integrity on compliance considerations and solid ethics
- Entrepreneurial spirit, team orientation, and ability to develop creative solutions to complex problems
Why Choose Us?- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
The salary range for this position is:
$178,500.00 - $257,833.33
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
