GenScript

Formulation Scientist

GenScript • $90K — $110K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's degree or PhD in pharmaceutical science, chemistry, biochemistry, chemical engineering, or related field (Master preferred)
  • Over 4 years of hands-on experience in nucleic acid delivery techniques, particularly lipid nanoparticle formulation
  • Strong background in lipid and polymeric nanoparticle delivery technologies
  • Extensive production and analytical characterization experience of nanoparticles
  • Proficient in various molecular biology techniques for mRNA and protein expression, as well as RNA-related analytics
  • Excellent communication and problem-solving skills
  • Ability to work collaboratively in a team environment.

Responsibilities

  • Develop innovative lipid nanoparticle formulations for mRNA, DNA, RNA, and peptide delivery
  • Create methods for characterizing and evaluating the physical characteristics of antibody-decorated LNPs
  • Enhance high-throughput LNP preparation and downstream processing to improve efficiency
  • Produce formulations for RNA projects and support functional assays for in vitro evaluation
  • Cultivate relationships with customers and participate in scientific meetings
  • Prepare study protocols, technical reports, and SOPs to advance mRNA product development
  • Collaborate with IP counsel in patent prosecution and monitor inventory for necessary materials.

Benefits

  • Medical, dental, and vision insurance
  • 401(k) retirement plan with company match that vests fully on day one
  • Paid parental leave after three months of employment
  • Comprehensive paid time off policy covering vacation, personal, sick, floating holidays, and company holidays
  • Short and long-term disability coverage
  • Legal assistance and supplemental insurance options including pet, critical illness, accident, and hospital indemnity insurance
  • Commuter benefits and well-being initiatives.
Full Job Description
GenScript is looking for a highly motivated and scientifically rigorous Nanoparticle Formulation Scientist to join our RNA team. This position will focus on developing novel lipid nanoparticle formulations for RNA delivery. Responsibilities: • Develop new lipid nanoparticle formulations (lipid or other polymers) platform for mRNA, DNA, RNA, peptide delivery, to achieve targeted delivery for different disease needs, like neuronal, brain, muscle, bone marrow cell, etc. • Develop method for characterizing and evaluating physical characteristics for antibody decorated LNPs. • Process development for high throughput LNP preparation and downstream process to improve production efficiency. • Produce formulations for related RNA projects, supporting functional assays for in vitro evaluation. • Maintain relationships with customers, participate in scientific meetings or customer meetings. • Write study protocols, technical reports, and SOPs to support mRNA product development projects. • Interact with IP counsel to assist with patent prosecution. • Monitors supply inventory and identifies any products required. • Maintains work area, equipment, department and all storage areas in a clean, neat and orderly manner. • Perform other duties as needed. Requirements: • Master or PhD's degree in pharmaceutical science, chemistry, biochemistry, chemical engineering or related field, Master is preferred • Strong knowledge of lipid and polymeric nanoparticle delivery technologies • >4 years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle formulation and characterization • Extensive experience with production and analytical characterization of nanoparticles • Proficiency in all molecular biology techniques for mRNA and protein expression (RT-PCR, ELISA, Western blot, Flow-cytometry, etc) and RNA-related analytics (ribogreen, gel electrophoresis, capillary electrophoresis, etc). • Works collaboratively with team members to support each other • Excellent communication and problem-solving skills • A sense of humility and an eagerness to continue to learn and contribute to a supportive team Benefit: • Medical Insurance/ Vision Insurance/ Dental Insurance • 401(k) & Retirement Savings Plan (RSP) • Short Term Disability Insurance • New Child Leave • Paid Time Off • Paid Company Holidays per year • Paid Sick Days (earned based on hours worked) • Compassionate Leave • Jury Duty Leave • Float day • Personal days Perks: • Free colleague meals during shift • Onsite massages Charis • Onsite gyms Compensation: Salary range: $90,000 - $110,000 total compensation, including bonus, depending on experience and qualifications. Benefits: Benefits include medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and company holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

About GenScript

GenScript Biotech Corporation is a global biotechnology group headquartered in Piscataway, New Jersey, United States. The company provides biological research services and products to scientists in pharmaceutical, biotechnology, agricultural, and academic settings. The company's services include gene synthesis, peptide synthesis, protein expression, antibody development, and in vitro and in vivo pharmacology studies. The company's products include molecular biology reagents, peptides, proteins, antibodies, and cell line development services. The company has subsidiaries in the United States, Europe, Japan, and China. GenScript was founded in 2002 by Frank Zhang and has grown to become a leading provider of gene synthesis services and other biotechnology products and services.
Learn more about GenScript
Size
3,000 employees
Industry
Founded
2002

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