AbbVie

Director

AbbVie • $150K — $180K *
Worcester, MA 01604In-Person
Pharmaceuticals & Biotech
11 - 15 years of experience
Today
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Job Overview by Ladders

Qualifications

  • Bachelor's, Master's, or PhD in Chemical Engineering, Biochemistry, Chemistry, or related sciences with extensive experience in biologics purification processes.
  • Proven technical expertise in biological process purification within pharmaceutical settings, capable of innovating product releases.
  • Expertise in bioprocess operations including chromatography and filtration techniques.
  • Proficient in operating and writing methods for AKTA chromatographic instruments.
  • Strong analytical skills with a solid understanding of techniques like HPLC and experience in experimental design and interpretation.
  • Excellent written and verbal communication skills with a track record of publications and presentations.
  • Ability to foster collaborative relationships across diverse groups and levels.

Responsibilities

  • Lead development, optimization, and tech transfer of purification processes for biologics candidates.
  • Actively influence development strategies on cross-functional CMC teams.
  • Execute lab operations as necessary to fulfill project deliverables in collaboration with team members.
  • Utilize creative problem-solving skills to advance project goals and propose innovative technologies.
  • Generate scientific proposals and evaluate regulatory advances to inform strategic responses.
  • Present scientific findings to functional leaders, maximizing impact through effective communication.
  • Mentor and supervise a team, ensuring accountability for performance and success.

Benefits

  • Comprehensive benefits package including paid time off, medical, dental, and vision insurance.
  • 401(k) plan for eligible employees.
  • Opportunity to participate in short-term incentive programs.
Full Job Description
Job Description

We are seeking a highly motivated Director reporting to head of Purification Development team to join the Purification Development group within Biologics Drug Substance Development organization. Our group is responsible for the end-to-end development from first in human process development to late-stage process optimization, process scale up, tech transfer to clinical and commercial sites, and process characterization for all biologics modalities at AbbVie Bioresearch Center in Worcester, MA. We contribute to the development of innovative and novel downstream technologies and create valuable intellectual property through the composition of matter and technologies resulting in cost-effective commercial manufacturing processes.

The core deliverable of downstream team is to develop robust manufacturing processes and advance innovative technologies using strong fundamentals. The ideal candidate will have prior biologics purification experience and a passion for hands-on laboratory process development. The candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization. The candidate must exhibit a collaborative nature in identifying process challenges on a wide range of projects, take part in a cross-functional team to deliver specific project needs, and take on a leadership role in developing and implementing solutions.

Responsibilities:
  • Lead development, optimization, scale-up, and tech transfer of purification processes for biologics candidates to support early and late-stage development
  • Represent purification development team and actively influence development strategy on cross-functional CMC teams
  • Transfer processes to pilot and GMP manufacturing
  • Be hands-on and execute lab operations when needed in collaboration with direct reports and/or purification development team members to meet project deliverables
  • Demonstrate creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. Proactively seek out new tools, techniques, and strategies to implement into the overall downstream platform
  • Advance scientific expertise and proactively demonstrates leadership by advises and sharing of expert opinions with subordinates, peers, and senior management.
  • Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies
  • Write technical publications, reports, presentations, and regulatory filings, including publishing research in peer-reviewed journals and presenting work at scientific conferences
  • Responsible for developing, communicating, and implementing the vision and strategy to fulfill functional goals and key scientific objectives. This also involves collaboration with experts within function to integrate scientific objectives into activities associated with development of new/improved products or technology.
  • Work efficiently, collaboratively, and cross-functionally toward project timelines and goals
  • Presents scientific concepts and results for functional scientific and non-scientific leaders as well as potential and existing partners. Maximizes impact and value of expertise.
  • Mentor/supervise a team and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals


Qualifications
  • Degree in Chemical Engineering, Biochemistry, Chemistry or other sciences with Bachelor's Degree or equivalent education and typically 18+ years of experience, MS or equivalent education and typically 16+ years of experience, PhD and typically 12+ years of biologics purification process development experience
  • Proven biologics process purification technical experience in pharmaceutical companies, with ability and prior experience in the innovation of new or improved product releases, generating original technical ideas and research or development strategies.
  • Must have expertise in developing standard bioprocess unit operations such as chromatography separations (resin/membrane: affinity, CEX, AEX, HIC, MM) and filtration operations (depth filtration, virus filtration, sterile filtration, TFF)
  • Proficient in writing methods and operating AKTA chromatographic instruments (such as AKTA Avant, AKTA Purifier, AKTA Pure, AKTA Ready or similar)
  • Able to independently design, execute, and interpret laboratory experiments to answer scientific questions
  • Has a strong understanding of analytical techniques, such as HPLC. Must be forward-thinking and be able to lead and contribute to scientific/technical discussions
  • Able to independently learn, understand and execute novel/advanced scientific techniques
  • Must have excellent attention to detail and ability to keep detailed written records
  • Proven record of authoring publications, technical reports, regulatory documents, and presentations
  • Has strong communication skills including verbal, written, and scientific data presentation
  • Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators.
  • Demonstrated ability to influence others in areas of science through excellent communication and prolific writing.


Preferred:
  • Direct experience leading tech transfer of downstream processes to GMP and/or pilot scale for mAb or other biologics
  • Direct experience in executing process characterization studies, including use of mechanistical modeling tools and/or statistical software (e.g., JMP, Minitab) to design, analyze, and interpret characterization results
  • Experience in developing automated workflows and skilled in applying AI and ML tools to optimize biologics CMC processes, strengthen data analysis, and improve predictive modeling.
  • Demonstrated strategic leadership with an innovative mindset to drive transformation and develop enhanced and efficient workflows


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

Work You’ll Do

At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

Explore Job Opportunities

AbbVie offers a wide range of job opportunities and career paths, providing a platform where professionals can propel their careers forward. From research and development to marketing and sales, the potential to make a significant impact is limitless.

Internship Programs

Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

Professional Growth and Development

We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

Benefits and Culture

AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

Hiring Process

Our hiring process is designed to ensure a match that will be beneficial both for the company and for your career aspirations. From resume submission to interview, each step is an opportunity to showcase your skills and fit with the AbbVie team.

Networking and Career Advancement

At AbbVie, networking doesn’t just enhance your career; it propels it. We encourage our employees to engage internally and externally to build relationships that foster personal and professional growth.

Join Our Team

Search open positions that match your skills and interests. We are looking for passionate, curious, and innovative team players who are ready to make a difference.

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Explore AbbVie Jobs

Whether you’re seeking to advance your career in a dynamic and empowering environment, or looking for a place where you can innovate, lead, and contribute to something bigger, AbbVie is the place for you. Join us in our mission to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.
Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Pharmaceuticals & Biotech
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ
ABBV
* Ladders Estimates

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