Guidehouse

Bioinformatics Scientist

Guidehouse$80K — $120K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's degree in bioinformatics, biostatistics, computational biology, or biological/life science.
  • At least two (2) years of data analysis experience.
  • Advanced proficiency in statistical modeling, machine learning, and integrative analysis.
  • Knowledge of NextGen sequencing techniques.
  • Experience with tools like R, Python, MATLAB, and cloud computing.

Responsibilities

  • Collaborate with scientists to design and manage data analysis.
  • Conduct analyses on diverse NextGen sequencing data types.
  • Apply computational data analysis to support biological discoveries.
  • Implement and refine analytical pipelines for single cell data.
  • Optimize and maintain bioinformatics pipelines for large-scale data.
  • Perform advanced statistical analyses to interpret complex datasets.
  • Train staff on bioinformatics tools and techniques.

Benefits

  • Medical, Rx, Dental & Vision Insurance
  • 401(k) Retirement Plan
  • Parental Leave
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement and Professional Development Opportunities
Full Job Description

Job Family:

Scientific Research & Analysis


Travel Required:

None


Clearance Required:

Ability to Obtain Public Trust

What You Will Do:
We are currently searching forBioinformatics Scientisttoprovidebioinformatics support to advance the institute research programs, with a primary focus on single cell and spatial omics data analysis. This is a full-time, on-site opportunity inDurham, NC.

  • Collaborate with scientists to design, analyze,manageand interpret all types of data.

  • Conduct analyses on NextGen sequencing data including data derived inChIP-Seq,RNA-Seq, miRNA-Seq and other experimental models.

  • Work with an interdisciplinary team to apply computational data analysis approaches to make biological discoveries.

  • Conduct analysis and interpretationondata from genomic platforms including expression, exon, tiling,promoterandothersarray types.

  • Work independently with research groups to develop, implement, and refine analyticalpipelinefor single cell data analysis.

  • Develop,optimize, andmaintainbioinformatics pipelines, scripts, and computational tools for large-scale data analysis (e.g., NGS,scRNA-seq, multi-omics).

  • Perform advanced statistical and computational analyses to interpret complex datasets and derive actionable biological insights.

  • Collaborate with scientists and researchers to design experiments, selectappropriate analyticalapproaches, and troubleshoot methodologies.

  • Integrate and analyze diverse genomic and multi-omicdatasets, including sequencing and public data sources.

  • Install, configure, and support scientific software across computing platforms; ensure reproducibility through standardized workflows and documentation.

  • Generate reports, visualizations, and presentations to communicate findings to scientific and technical audiences.

  • Evaluate and implement new bioinformatics tools, statistical methods, and computational approaches based on current literature and research needs.

  • Provide training and technical guidance to staff on bioinformatics tools, pipelines, and data analysis techniques.

  • Maintain detailed documentation, laboratory records, and progress reports; present findings at meetings and contribute to publications.

  • Support interdisciplinary collaborations and contribute to advancing researchobjectivesaligned with organizationalmission.

  • Must be able to obtain and maintain a Federal or DoD 7public trust8; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What You Will Need:

  • Masters degree in bioinformatics,biostatistics,computationalbiologyor biological/life science.

  • At leastTWO (2)years ofdata analysisexperience.

  • Advancedproficiencyindisciplines such asstatistical modeling, machine learning, and integrative analysis to extract biologically meaningfulinsights from complex cellular systems.

  • Knowledgeable with avariety of next gen sequencing techniques.

  • Experience working withanalyticaltools,softwareand platforms such as, but not limited to, R, Python, MATLAB, SAS, PERL, Java, Shell, Bash, Seurat /Scanpy,Linux,Unix,Bioconductor,Cloud computing,High-PerformanceComputing (HPC).

  • Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred

What Would Be Nice To Have:

  • PhD preferred

  • Strong verbal and writtencommunication skills

  • Familiar with multiplenext gen sequencingtechniques

  • Ability to collaborate closely with investigators and multidisciplinary teams to design analytical strategies, ensure data quality, interpret results, and translate findings into actionable scientific conclusions.


What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

  • Medical, Rx, Dental & Vision Insurance

  • Personal and Family Sick Time & Company Paid Holidays

  • Parental Leave

  • 401(k) Retirement Plan

  • Group Term Life and Travel Assistance

  • Voluntary Life and AD&D Insurance

  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

  • Transit and Parking Commuter Benefits

  • Short-Term & Long-Term Disability

  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

  • Employee Referral Program

  • Corporate Sponsored Events & Community Outreach

  • Care.com annual membership

  • Employee Assistance Program

  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

  • Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is a management consulting firm headquartered in Washington, D.C. The firm provides consulting services to clients in the public and commercial sectors, with a focus on energy, financial services, healthcare, national security, and aerospace and defense. Guidehouse was founded in 2018 as a spin-off from PwC. The firm has over 7,000 employees and operates in more than 50 locations worldwide.
Learn more about Guidehouse
Size
8,000 employees
Industry
Founded
2018

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