Merck & Co, Inc

Associate Principal Scientist, Discovery Analytical Research

Merck & Co, Inc$142K — $224K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. in Analytical Chemistry or related field with 4+ years of biopharmaceutical industry experience.
  • Deep expertise in separation techniques (e.g., UPLC, LC-CAD) for vaccines.
  • Strong background in biophysical techniques (e.g., DLS, DSC) relevant to vaccine analysis.
  • Experience with automation workflows using liquid handling platforms (e.g., Tecan, Bravo).
  • Demonstrated ability through publications and conference presentations.
  • Excellent communication skills and ability to work collaboratively under tight deadlines.

Responsibilities

  • Represent the research group in project teams and guide scientific strategy.
  • Develop and troubleshoot advanced analytical methods, focusing on biophysical techniques.
  • Drive innovation in analytical technologies and solve complex problems.
  • Collaborate with multidisciplinary teams to achieve organizational goals.
  • Mentor junior scientists and foster a learning culture.
  • Maintain high standards of data integrity and documentation.
  • Adapt and thrive in a dynamic, fast-paced team environment.

Benefits

  • Join an innovative team focused on impactful drug discovery.
  • Opportunities for professional growth and advancement.
  • Encouragement for publication and presentation at scientific forums.
Full Job Description

Job Description

The Discovery Analytical Research group in West Point, Pennsylvania is seeking application for an Associate Principal Scientist position to drive innovation in analytical measurement technologies, enabling the discovery of new drug candidates across various modalities. Key deliverables will include the development, implementation, and execution of analytical measurement technologies that accelerate the pace of discovery research and influence molecular design. The successful candidate must be able to collaborate in a dynamic, integrated, and multidisciplinary team environment. The primary role of the successful candidate will be to lead the development and application of advanced analytical and biophysical characterization strategies for our early-stage vaccines pipeline, playing a critical role in influencing molecular design, candidate selection, and manufacturability through data-driven insights and the deployment of novel technologies.

Primary Responsibilities:

  • Represent the discovery analytical research group in project teams, provide technical guidance, and drive scientific strategy.

  • Develop, implement, and troubleshoot advanced analytical methods, primarily separation-based techniques and biophysical techniques utilizing automation.

  • Solve complex problems and drive innovation in analytical measurement technologies.

  • Collaborate in multidisciplinary teams, foster partnerships with discovery groups, and contribute to organizational goals.

  • Mentor and develop junior scientists and promote a culture of learning and innovation.

  • Ensure high standards of data integrity and documentation.

  • The successful candidate must be able to effectively collaborate in a fast-paced, integrated, multidisciplinary team environment.

Education Minimum Requirements:

  • Ph.D. in Analytical Chemistry or related field with 4+ years of biopharmaceutical industry experience.

Required Experience and Skills:

  • Deep expertise in separation techniques (UPLC, LC-CAD, CE-SDS, SEC, BCA, Western) for vaccines.

  • Strong experience in biophysical techniques (e.g. DLS, SLS, MFI, DSC, SAXS) for vaccines.

  • Experience with automation workflows, including liquid handling platforms (e.g., Tecan, Bravo, NIMBUS)

  • Demonstrated scientific ability through publications in peer reviewed journals and presentations in scientific conferences.

  • Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills.

  • Ability to deliver complex objectives under challenging timelines in a rapidly changing environment.

  • Ability to work in a team environment with cross-functional interactions.

Preferred Experience and Skills:

  • Experience with electronic laboratory notebook applications and good documentation practices.

  • Familiarity with coding/scripting (e.g., Python, R) for automation or data analysis

Why Join Us?

Be part of a dynamic, innovative team. Lead impactful research and contribute to drug discovery. Opportunities for professional growth and publication.

#AR&D

Required Skills:

Adaptability, Adaptability, Analytical Chemistry, Analytical Method Development, Assay Development, Automation, Biological Assay Development, Biopharmaceutical Industry, Biopharmaceuticals, Biopharmaceutics, Cell-Based Assays, Chromatographic Techniques, Cross-Functional Teamwork, Drug Discovery Process, External Collaboration, Foster Innovation, High Resolution Mass Spectrometry (HRMS), Laboratory Documentation, Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry Analysis, Multidisciplinary Collaboration, Optimism, Pharmaceutical Biology, Process Analytical Technology (PAT), Protein Analysis {+ 2 more}

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

n/a

Job Posting End Date:

07/8/2026

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

About Merck & Co, Inc

Schering-Plough Corporation is a major U.S.-based manufacturer of pharmaceuticals. It operates in three segments: Prescription Pharmaceuticals, Animal Health, and Consumer Health Care. Schering-Plough develops products targeting on allergy, cancer, hepatitis, cardiovascular, central nervous system, respiratory system, and more.  It was founded in 1851 by Ernst Christian Friedrich Schering as Schering AG in Germany. Schering-Plough manufactured several pharmaceutical drugs, the most well-known of which were the allergy drugs Claritin and Clarinex, an anti-cholesterol drug Vytorin, and a brain tumor drug Temodar. It also developed drugs targeting on central nervous system and the respiratory system. Schering Plough also owned and operated the major foot care brand name Dr. Scholl's and the skin care line Coppertone. These also became a part of the new company. Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA), a membership which is also maintained by the new Merck.

Merck & Co, Inc Careers

Join the visionary team at Merck & Co, Inc, a global leader in healthcare dedicated to advancing the world of medicine. As part of our professional community, you'll find dynamic job opportunities that foster innovation and leadership across various fields. Merck & Co, Inc is not just a company; it's a place where you can make a difference.

Work You’ll Do

At Merck & Co, Inc, we are committed to improving global health through groundbreaking research and innovative healthcare solutions. Our team is at the forefront of developing new therapies and vaccines that significantly impact public health worldwide. By joining us, you will collaborate with some of the brightest minds in the industry, using your skills to contribute to projects that save and improve lives around the globe.

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Whether you're seeking an internship, a graduate opportunity, or a professional position, Merck & Co, Inc offers a range of career paths in environments that promote rapid professional growth and development. Explore job opportunities in research, digital transformation, manufacturing, and more, all while benefiting from a culture that supports diversity and inclusion.

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Merck & Co, Inc is an ideal environment for those who lead with curiosity and the drive to innovate. Our leadership is committed to fostering a culture where inventive thinking and collaboration are encouraged, making it a perfect place for professionals who seek to make an impact through their work.

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With Merck & Co, Inc, you are not just getting a job; you're gaining access to unparalleled career development opportunities. Enhance your skills through diverse training programs, workshops, and continuous learning courses designed to help you grow at every stage of your career.

Benefits and Culture

We understand that our employees are our greatest asset, which is why we offer competitive benefits designed to support the health and well-being of you and your family. From comprehensive health care coverage and retirement plans to flexible working conditions and wellness programs, our benefits package is designed to meet the diverse needs of our team members.

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Ready to advance your career at Merck & Co, Inc? Search open positions that match your skills and interests. We are continuously hiring and looking for passionate, creative, and solution-driven team players. Prepare your resume, sharpen your interview skills, and become part of a company that's dedicated to making a difference.

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Learn more about Merck & Co, Inc
Size
68,000 employees
Market Cap
$282.6 billion
Industry
Net Income
$7 billion
Founded
1668
5 Year Trend
+4.1%
Revenue
$47.9 billion
NASDAQ

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