Amgen Inc

ADC Development: Organic and Conjugation Chemist

Amgen Inc$123K — $167K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Doctorate in organic chemistry, biochemistry, chemical biology, medicinal chemistry, or equivalent experience.
  • Master's degree with 3 years of lab experience or Bachelor's with 5 years of lab experience.
  • Postdoctoral research or 2 years of synthetic chemistry experience preferred.
  • Familiarity with ADC linker and payload synthesis and purification.
  • Experience in the bioconjugation process is an advantage.
  • Proficient in NMR, MS, and chromatography techniques, including HPLC and size exclusion.

Responsibilities

  • Design and synthesize novel organic linkers and payloads for ADCs.
  • Purify and characterize antibody drug conjugates for therapeutic discovery.
  • Analyze, interpret, and document scientific data and results.
  • Communicate project updates and outcomes regularly to the team.
  • Collaborate effectively across diverse scientific teams.

Benefits

  • Work in a state-of-the-art research facility in Thousand Oaks, CA.
  • Be part of innovative projects in ADC therapeutics and novel modalities.
  • Engage in a collaborative environment with diverse scientific teams.
  • Contribute to meaningful work that aims to improve patient outcomes.
Full Job Description
Career Category
Scientific
Job Description

Senior Scientist - Protein Engineering - ADC Development: Organic and Conjugation Chemist

This could be your everyday

Let's do this. Let's change the world.

The hybrid Modality Group in the Protein Engineering Department at Amgen is seeking a highly motivated organic chemist to join us in the state-of-the-art research facility at the Amgen headquarters campus located in Thousand Oaks, CAThe qualified candidate will work at the interface of synthetic chemistry, biochemistry, and chemical biology to apply their synthetic skills in developing ADC therapeutics and cutting-edge novel modalities.
  • Responsibilities including (but not limited to) the design, synthesis, purification and characterization of novel organic linkers, peptides, and payloads for antibody drug conjugates.
  • Design, synthesis, purification, and characterization of antibody drug conjugates for therapeutic discovery.
  • The scientist will review, analyze, and interpret scientific data and results; provide regular updates, documentation, and/or communication on project results.

Win

Here's what it takes to Win

We are all different, yet we all use our unique contributions to serve patients. The dedicated individual we seek is a scientist with these qualifications.

Basic qualifications
  • Doctorate degree specializing in organic chemistry, biochemistry, chemical biology, medicinal chemistry OR
  • Master's degree and 3 years of laboratory experience OR
  • Bachelor's degree and 5 years of laboratory experience

Preferred qualifications
  • Posdoc or 2 years of synthetic chemistry experience preferred.
  • Experience in the synthesis and purification of ADC linker and payloads.
  • Experience in bioconjugation process is preferred.
  • Experience with peptide synthesis and purification is preferred.
  • A robust understanding of structural determination using NMR and MS techniques and proficient with a range of chromatography methods (e.g. HPLC, RP HPLC, ion exchange, size exclusion chromatography)
  • Demonstration of good lab practices, with particular attention to safety


  • Strong written and verbal communication skills
  • Ability to work comfortably within a large team of scientists and engineers with diverse technical and cultural backgrounds.

Salary Range
123,777.00USD -167,463.00 USD

About Amgen Inc

Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases. The company is values-based and deeply rooted in science and innovation to transform new ideas and discoveries into medicines for patients with serious diseases. They offer products for treating illness in the areas of oncology/hematology, cardiovascular, inflammation, bone health, nephrology, and neuroscience.

Amgen Inc Careers

Join the dynamic team at Amgen Inc, a biotechnology pioneer dedicated to discovering, developing, and delivering innovative human therapeutics. At Amgen, we offer more than just job opportunities; we invite you to be part of a culture of leadership, diversity, and innovation.

Work You’ll Do

At Amgen Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that brings real solutions to patients worldwide. Our commitment to your career growth is evident in our professional development and leadership training programs designed to nurture your potential.

Innovate and Lead

Amgen Inc stands at the forefront of biotech innovation. Our team is constantly pushing the boundaries of science and technology. By joining us, you will contribute to a legacy of medical breakthroughs that improve the lives of millions.

Be Part of a Great Team

Amgen’s inclusive culture and commitment to diversity are integral to our success. We believe in empowering our employees with the skills and networking opportunities they need to thrive. Our team’s collaboration is the key to developing groundbreaking solutions.

Future-Proof Your Career

Amgen Inc offers a variety of career paths, from research and development to marketing and sales, providing near-limitless opportunities for advancement. Whether you are looking for a full-time position, an internship, or a leadership role, Amgen has a place for you. Our robust benefits package supports the well-being of our employees and their families, contributing to a fulfilling work-life balance.

Explore Job Opportunities

Discover the impact you can make with a career at Amgen Inc. We are hiring creative, curious, and motivated individuals ready to face challenges head-on. Explore our open positions that match your skills and interests.

Stay Connected

Join our team and stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. See what exciting and rewarding opportunities await.

Interview and Resume Tips

Prepare for your future with Amgen Inc by utilizing our resources designed to enhance your interview skills and polish your resume. Our hiring process is designed to identify and attract professionals who are driven to make a difference.

Amgen Inc—Where Careers Grow

At Amgen Inc, we are committed to turning innovative science into value for patients. If you are passionate about joining a team that makes a difference, search Amgen jobs today and take the first step towards a fulfilling career.

SEARCH AMGEN JOBS

READ CAREERS BLOG

JOB ALERT EMAILS

Join us at Amgen Inc, where your career can flourish in an environment of innovation, leadership, and growth.
Learn more about Amgen Inc
Size
24,200 employees
Market Cap
$141.2 billion
Industry
Net Income
$7.2 billion
Founded
1980
5 Year Trend
+2.5%
Revenue
$25.4 billion
NASDAQ

Similar Jobs

More Jobs at Amgen Inc

More Pharmaceuticals & Biotech Jobs

Find similar ADC Development: Organic and Conjugation Chemist jobs: