Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$109K - $173K *

Elevate your career by partnering with us to enhance financial forecasting and reporting processes. Leverage your analytical skills to improve business intelligence systems and drive key performance i...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$190K - $210K *

Transform the owner activation journey by streamlining processes from agreement to live listing. Drive metrics on activation rates and retention while collaborating with teams to enhance onboarding ef...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$198K - $330K *

Lead a dynamic team to shape technology portfolio management, ensuring strategic alignment and delivery excellence across product and engineering initiatives while fostering collaboration and accounta...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Elevate manufacturing excellence by optimizing processes and driving continuous improvement initiatives. Collaborate with cross-functional teams to enhance safety, quality, and productivity in a dynam...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$128K - $250K *

Champion the development of winning strategies for complex public sector opportunities, engaging directly with customers and stakeholders to shape solutions and lead major pursuits from identification...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Join a team that's dedicated to enhancing client relationships and driving business growth. This role involves managing complex accounts, ensuring delivery assurance, and developing strategic account...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$158K - $199K *

Empower innovation in ad formats by leading cross-functional teams to create engaging user experiences. Drive growth for new advertisers while managing strategic partnerships and executing impactful p...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$130K - $140K *

Elevate project delivery by leading Agile initiatives, managing fixed price and outcome-based projects, and driving operational excellence across diverse client engagements...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$180K - $220K *

Lead the infrastructure engineering team to drive strategic initiatives, enhance developer productivity, and ensure reliability as the organization scales towards ambitious growth targets, including A...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$135K - $160K *

Join us to lead the deployment of AI-driven ERP solutions, enhancing SAP S/4HANA capabilities. Collaborate with cross-functional teams to ensure scalable, reliable, and secure automation across critic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Shape the future of education by owning content strategy for assessments. Collaborate with experts and district leaders to enhance quality and drive adoption, leveraging insights to inform product dir...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $150K *

Join a team that's redefining HR support for a growing fellowship program. You'll oversee onboarding, advise managers, and enhance employee relations while ensuring a seamless experience for fellows a...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$123K - $172K *

Join our dynamic team to tackle real challenges in SaaS management, enhancing IT and Security ecosystems. Collaborate with talented professionals to build impactful software while leveraging AI for ef...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$77K - $118K *

Drive the evolution of scalable, secure platforms by architecting solutions that enhance network intelligence and application delivery, collaborating with cross-functional teams to optimize performanc...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$179K - $204K *

Drive innovation by architecting and building scalable greenfield products, collaborating with cross-functional teams to transform consumer needs into impactful features while mentoring fellow enginee...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $214K *

Shape enterprise data architectures by leveraging your expertise in Databricks and modern cloud platforms. Collaborate with clients to design scalable solutions that drive analytics, AI/ML, and data g...

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $135K *

Transform the insurance landscape by leading product innovation and development initiatives, enhancing personal Property products to meet member needs and drive profitable growth while ensuring market...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $150K *

Advance your career by leading product strategy for supply chain orchestration. Drive technical decisions, collaborate with cross-functional teams, and leverage AI to enhance workflows, ensuring measu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$115K - $169K *

Drive successful project execution by managing capital projects from concept to completion, ensuring adherence to design, scope, and milestones while coordinating with clients and teams for optimal re...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$120K - $145K *

Help us drive technical strategy and solutions for enterprise clients, addressing security challenges and delivering impactful demonstrations. Collaborate with cross-functional teams to translate comp...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$260K - $300K *

Advance your career by driving new business growth through consultative sales. Leverage your technical expertise to engage customers, manage sales processes, and foster strong relationships, ensuring...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$132K - $165K *

Shape the future of billing and collections by driving product strategy and enhancing user experiences. Collaborate with cross-functional teams to deliver reliable payment solutions that boost revenue...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$117K - $129K *

Lead the charge in optimizing operational performance for solar energy projects. Collaborate with engineers to analyze performance data, develop solutions, and ensure project success, while fostering...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$150K - $180K *

Lead the product vision and strategy for a cutting-edge cloud service, shaping capabilities and defining AI-driven insights while collaborating with engineering and operations teams to ensure market a...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$138K - $185K *

Transform your career by leading enterprise data and AI architecture initiatives. Collaborate with cross-functional teams to drive technology adoption and ensure alignment with business needs while in...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.