Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$85K - $130K *
Champion innovative control systems for industrial solutions, leading design and development projects. Collaborate with teams to ensure products meet market demands while transitioning designs to manu...
1 week ago
User Experience Operations Lead
$177K - $290K *
Transform UX operations by unifying decision-making and enhancing workflows across disciplines. Drive continuous improvement through automation and strategic partnerships, ensuring a cohesive UX organ...
Reposted today
Senior Automation Engineer - Ansible
$104K - $166K *
Accelerate automation initiatives by developing end-to-end solutions using Ansible, Python, and RESTful APIs. Collaborate with cross-functional teams to enhance operational efficiency and ensure compl...
2 weeks ago
Application Engineer (Switchgear)
$95K - $115K *
Empower your career by bridging sales and engineering as a key technical resource. You'll scope, quote, and support customer needs for low and medium-voltage switchgear solutions, ensuring alignment w...
3 weeks ago
Engineering Manager - Secure Access
$140K - $170K *
Advance your career by leading a dynamic team in developing secure access solutions. Drive technical direction, manage project delivery, and mentor engineers while balancing customer reliability with...
3 weeks ago
Solutions Engineer Technical Lead
$95K - $115K *
Lead client interactions and drive technology solutions by leveraging AI and best practices. Collaborate with teams to enhance efficiency, mentor developers, and ensure alignment with business goals w...
5 days ago
Senior Software Engineer, Backend (Consumer - Risk)
$186K *
Unlock potential by leading the design and delivery of innovative risk systems, optimizing fraud detection and mitigation processes, and mentoring engineers to enhance operational excellence in a dyna...
Today
$150K - $180K *
Join a transformative team as an Engineering Manager to lead engineering initiatives, inspire innovation, and drive technical excellence in revolutionizing healthcare technology while fostering profes...
Reposted 1 week ago
$95K - $115K *
Elevate your career by building and maintaining CI/CD pipelines, administering servers, and leading DevOps initiatives. Collaborate with teams to enhance application performance and security while men...
4 days ago
$170K - $230K *
Join a team that's redefining SoC design by owning subsystem development, integrating third-party IP, and optimizing PPA for next-gen architectures. Contribute across all design stages and drive impac...
1 week ago
Principal Product Manager, Ads Delivery & Optimization
$200K - $335K *
Drive strategy and execution for Ads Delivery & Optimization, enhancing advertiser outcomes through advanced bidding, ranking, and measurement systems. Collaborate with cross-functional teams to innov...
4 weeks ago
Director of Product Management, Platform
$183K - $230K *
Lead the charge in shaping our platform strategy, overseeing integrations, pricing, and customer experience. Collaborate with cross-functional teams to enhance product offerings and drive growth in a...
1 week ago
$170K - $250K *
Lead the charge in building high-throughput systems as you manage a team of engineers. Drive technical excellence and team growth while collaborating across functions to deliver innovative solutions i...
1 week ago
Sr. Full Stack Engineer - Infrastructure Team (Remote)
$140K - $215K *
Elevate our cloud infrastructure by developing robust tools for deployment, monitoring, and maintenance. Join a dynamic team of engineers focused on enhancing CI/CD processes and driving developer pro...
Reposted 2 weeks ago
$130K - $160K *
Elevate cloud security and reliability by leading DevOps practices across teams. You'll optimize AWS and GCP environments, enhance CI/CD pipelines, and ensure cost-effective engineering tools, driving...
1 week ago
REMOTE- Senior Platform Software Engineer- Oracle Health
$87K - $209K *
Join a dynamic team to design and implement backend services, enhancing developer tooling and integration frameworks. Drive improvements in performance and resilience while collaborating with cross-fu...
1 week ago
Sr. Manager, Software Engineering - Computer Backup
$205K - $255K *
Join a team that's shaping the future of data protection by leading the Computer Backup engineering team. Drive technical direction, manage budgets, and enhance collaboration across desktop and backen...
6 days ago
Software Engineering - Lead Data Scientist
$138K - $165K *
Shape the future of consumer applications by leading machine learning and Generative AI initiatives. Build robust data pipelines, develop and deploy models, and drive business impact through experimen...
5 days ago
Forward Deployed Engineer (TypeScript + AI) - Remote - USA
$120K - $145K *
Accelerate progress at the intersection of engineering and AI, embedding with enterprise teams to architect and deliver robust AI solutions that meet real-world demands in regulated industries...
1 week ago
Manufacturing Quality Engineer, Data Center Equipment
$110K - $130K *
Transform the quality landscape of data center equipment by overseeing supplier audits, inspections, and continuous improvement initiatives. Collaborate with cross-functional teams to ensure complianc...
3 days ago
$95K - $115K *
Empower innovation as you design complex electrical systems, lead projects, mentor teams, and ensure high-quality deliverables. Collaborate closely with multi-disciplinary teams, utilizing advanced BI...
Reposted 3 weeks ago
$95K - $115K *
Oversee complex electrical design projects and deliver fully constructible BIM models. Collaborate with cross-functional teams, mentor peers, and ensure compliance with safety standards while developi...
Reposted 3 weeks ago
Senior Front-End Engineer (Angular)
$120K - $145K *
Join a team that's shaping the future of consumer payments by designing and building scalable Angular applications. Collaborate across disciplines to create intuitive user experiences while maintainin...
Today
Product Engineer II - Web Services
$79K - $133K *
Elevate progress at the forefront of ArcGIS Hub by transforming customer workflows, communicating priorities, and enhancing geospatial collaboration through innovative product management...
Reposted today
Solution Architect, Forward Deployed AI
$135K - $160K *
Transform AI pilots into secure, reliable production systems by designing innovative solutions and collaborating with cross-functional teams to ensure responsible enterprise adoption of AI technologie...
Today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.