Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$120K - $145K *

Lead quantitative user research across product lines, shaping strategy and answering critical questions with data-driven insights. Collaborate with teams to prioritize research that mitigates risk and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Transform clinical data programming by developing scalable Python solutions, modernizing SAS workflows, and building reusable frameworks to enhance clinical trial data delivery and influence technolog...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Empower the development of innovative banking solutions by driving product strategy, collaborating across teams, and delivering scalable capabilities that enhance customer experiences and meet busines...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $160K *

Transform the future of finance by building backend systems that enhance AI spend visibility and management. Collaborate with cross-functional teams to deliver reliable data solutions and drive impact...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Unlock potential by guiding organizations through digital transformation with your expertise in AI-powered DevSecOps. Collaborate with cross-functional teams to drive successful platform adoption and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$105K - $231K *

Accelerate progress at the forefront of SAP integration, driving complex data exchanges and ensuring compliance with DoD standards while enhancing transportation operations across diverse systems...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $220K *

Transform your career by leading the product vision for a critical billing module. Collaborate with cross-functional teams to enhance telecom billing systems, ensuring operational efficiency and excep...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$134K - $185K *

Empower HR processes by leading IT solutions development and governance. Collaborate with HR leaders to align technology strategies with business needs, ensuring effective implementation and managemen...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$269K - $370K *

Join a team that's transforming AI into a measurable business capability. Lead strategic initiatives, optimize operations, and collaborate across functions to enhance AI adoption and efficiency while...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $144K *

Lead the charge in designing and implementing advanced building automation systems for critical infrastructure projects, ensuring seamless integration and optimal performance while managing teams and...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $180K *

Join a team that's redefining the buyer experience in B2B software. As a Principal Product Manager, you'll lead strategy, drive product delivery, and enhance buyer trust across multiple platforms, ens...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$115K - $135K *

Engage with engineers and executives to create compelling technical content that showcases innovative CAD solutions. Deliver presentations, demos, and tutorials that highlight product features and the...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$109K - $173K *

Elevate your career by partnering with us to enhance financial forecasting and reporting processes. Leverage your analytical skills to improve business intelligence systems and drive key performance i...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$190K - $210K *

Transform the owner activation journey by streamlining processes from agreement to live listing. Drive metrics on activation rates and retention while collaborating with teams to enhance onboarding ef...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$198K - $330K *

Lead a dynamic team to shape technology portfolio management, ensuring strategic alignment and delivery excellence across product and engineering initiatives while fostering collaboration and accounta...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$128K - $250K *

Champion the development of winning strategies for complex public sector opportunities, engaging directly with customers and stakeholders to shape solutions and lead major pursuits from identification...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Join a team that's dedicated to enhancing client relationships and driving business growth. This role involves managing complex accounts, ensuring delivery assurance, and developing strategic account...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$158K - $199K *

Empower innovation in ad formats by leading cross-functional teams to create engaging user experiences. Drive growth for new advertisers while managing strategic partnerships and executing impactful p...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$180K - $220K *

Lead the infrastructure engineering team to drive strategic initiatives, enhance developer productivity, and ensure reliability as the organization scales towards ambitious growth targets, including A...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$135K - $160K *

Join us to lead the deployment of AI-driven ERP solutions, enhancing SAP S/4HANA capabilities. Collaborate with cross-functional teams to ensure scalable, reliable, and secure automation across critic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Shape the future of education by owning content strategy for assessments. Collaborate with experts and district leaders to enhance quality and drive adoption, leveraging insights to inform product dir...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $150K *

Join a team that's redefining HR support for a growing fellowship program. You'll oversee onboarding, advise managers, and enhance employee relations while ensuring a seamless experience for fellows a...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$123K - $172K *

Join our dynamic team to tackle real challenges in SaaS management, enhancing IT and Security ecosystems. Collaborate with talented professionals to build impactful software while leveraging AI for ef...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$77K - $118K *

Drive the evolution of scalable, secure platforms by architecting solutions that enhance network intelligence and application delivery, collaborating with cross-functional teams to optimize performanc...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$179K - $204K *

Drive innovation by architecting and building scalable greenfield products, collaborating with cross-functional teams to transform consumer needs into impactful features while mentoring fellow enginee...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.