Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$175K - $210K *

Join us to lead the development of cutting-edge Operational AI solutions, collaborating with Global 2000 engineering teams. Drive technical integrity from architecture to production, ensuring impactfu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$141K - $205K *

Unlock potential by serving as a strategic HR advisor, delivering impactful consultations and solutions across various HR topics to optimize workforce performance and support business growth in a dyna...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $187K *

Transform public sector sales by driving growth strategies, building executive relationships, and leading complex pursuits. Leverage your expertise in IT consulting and digital transformation to close...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $155K *

Join us to lead security and compliance initiatives within a dynamic platform team. You'll leverage your expertise to enhance production infrastructure, ensuring robust protection and reliability for...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$150K - $180K *

Transform the future of intelligent compiler technologies by designing and optimizing advanced systems that enhance developer productivity and system performance across software and hardware boundarie...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Elevate employee experiences by designing and implementing HR solutions. Lead technical projects, optimize integrations with Microsoft 365, and mentor developers to enhance ServiceNow capabilities and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$84K - $131K *

Lead the charge in developing innovative Java applications, leveraging Spring Boot and DevSecOps practices. Collaborate with cross-functional teams to enhance web-based solutions while integrating AI...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$144K - $242K *

Lead the development of an AI-driven seller experience, shaping product strategy and engaging homeowners throughout their selling journey. Collaborate across teams to define success metrics and protot...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$90K - $110K *

Join a dynamic team as you drive growth by designing tailored software solutions for schools. Leverage your technical expertise to engage clients, deliver impactful demos, and collaborate with cross-f...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $200K *

Manage advanced product development programs for data center infrastructure, collaborating with cross-functional teams to drive comprehensive manufacturing strategies, optimize operations, and ensure...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$119K - $140K *

Shape the future of technology in healthcare by leading development efforts, leveraging AI tools, and ensuring high-quality digital deliverables across multiple platforms. Collaborate with creative te...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $151K *

Advance your career by leading financial reporting and forecasting efforts. Collaborate across departments to analyze data, streamline processes, and support strategic planning in a dynamic, high-grow...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$84K - $187K *

Join the AI Automation team to innovate and implement AI solutions that enhance efficiency and security. Collaborate with experts to build automations, connect systems, and experiment with cutting-edg...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Unlock potential by leading technical solutions for enterprise SaaS implementations. Collaborate closely with clients to translate business needs into actionable technical designs, ensuring successful...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $159K *

Optimize client partnerships by driving strategic outreach and proposals. Leverage AI tools to enhance sales cycles, mentor peers, and contribute to revenue growth through long-term relationships and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$240K - $330K *

Unlock potential by leading a global enablement team to develop and implement a comprehensive strategy that enhances sales effectiveness and drives revenue growth across all customer-facing roles...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $115K *

Innovate testing strategies and enhance software quality through automated and manual verification. Collaborate across teams to ensure compliance and optimize processes while leveraging AWS and full-s...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Elevate customer experiences by driving the integrations roadmap, enhancing capabilities, and collaborating across teams to deliver impactful solutions that meet compliance needs and improve product o...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Architect and enhance scalable infrastructure and CI/CD pipelines, collaborating across engineering teams to implement innovative cloud technologies and open-source solutions for optimal product deliv...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$217K - $303K *

Lead the charge in redefining moderation on a global scale, transforming community enforcement through innovative AI/ML solutions. Shape user experiences and drive impactful product strategies to supp...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Media

$183K - $216K *

Take ownership of the scientific and product roadmap for monetization, leading audience creation and measurement methodologies. Collaborate with cross-functional teams to drive product strategy and in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$360K - $495K *

Lead the charge in product management, driving strategy and execution across multiple product pillars. Build a high-performing team, establish operational excellence, and ensure customer-centric outco...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Champion the security strategy for a cutting-edge platform, focusing on supply chain security, code scanning, and threat modeling. Collaborate with teams to enhance security practices and drive innova...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Transform application deployment by collaborating with teams to streamline processes, enhance automation, and ensure high-quality releases across environments while mentoring junior members and drivin...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$84K - $87K *

Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.