Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$160K - $208K *

Transform our technology infrastructure by enhancing automation, troubleshooting issues, and fostering collaboration. Bring your expertise to support a scalable infrastructure platform that manages di...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $130K *

Unlock potential by leading complex data engineering initiatives, enhancing platform reliability, and mentoring junior engineers. Collaborate across teams to design and implement scalable solutions wh...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $187K *

Transform the Time & Attendance engineering team by leading technical delivery, fostering collaboration, and driving platform modernization to enhance healthcare workforce solutions and ensure data ac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $190K *

Shape the future of data engineering by leading architectural improvements, enhancing data quality, and driving technical initiatives across diverse business domains. Collaborate with stakeholders to...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Partner with us to transform customer experience operations into a seamless, data-driven journey. Your leadership will unify departments for consistency, enabling effective strategies that enhance cus...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$199K - $230K *

Drive innovation by deploying and optimizing cloud infrastructure across federal environments. Leverage your expertise in AWS, Kubernetes, and automation tools to enhance platform scalability and secu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Drive innovation in digital experiences by building and optimizing high-performing web applications. Collaborate with creative teams to enhance customer engagement across platforms while managing the...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $212K *

Pioneer innovative IAM strategies to enhance security across cloud and on-premise infrastructures. Collaborate with cross-functional teams to implement robust identity governance and access management...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$168K - $219K *

Join a dynamic team as a Sr. Solutions Engineer, leveraging your expertise to solve complex business challenges for mid-market customers, driving impactful solutions and fostering collaboration to enh...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Join a team that's shaping developer experiences by creating impactful tutorials, demo apps, and tools. Collaborate across departments to enhance adoption and usability of Render's products while test...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$115K - $162K *

Develop and optimize backend features for a Rust-based graph data service, enhancing reliability and scalability while collaborating across teams to deliver impactful solutions for GitLab's platform...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $125K *

Optimize game development by enhancing build systems and automating infrastructure. Collaborate with teams to ensure reliable deployments across multiple platforms, driving efficiency and innovation i...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $130K *

Accelerate your career by managing a portfolio of mid-market accounts, ensuring customer success through strategic engagement, relationship building, and AI-driven insights. Drive measurable outcomes...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$103K - $152K *

Join us as a hands-on technical leader, driving solution delivery while mentoring your team. You'll configure, customize, and troubleshoot systems, ensuring high-quality outcomes and fostering team gr...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$147K - $205K *

Innovate with us to lead global Technical Support Engineering operations, enhancing customer experience through effective problem-solving, operational excellence, and team development. Drive continuou...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Engineer critical electrical and mechanical systems for data centers, leading field support, troubleshooting, and reliability improvements while developing operational standards and mentoring teams to...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$68K - $189K *

Empower digital transformation by designing and developing scalable, secure applications. Lead teams in full-stack development, architecture, and Agile practices to deliver innovative solutions that e...

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Deliver innovative routing solutions for enterprise-scale contact centers. Design and build a robust routing engine that intelligently distributes interactions across various channels, ensuring high a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$165K - $225K *

Unlock your potential by designing and operating robust Kubernetes infrastructure. Collaborate with cross-functional teams to ensure high-performance, reliable systems that support enterprise-scale AI...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$155K - $180K *

Drive successful delivery of complex, multi-year programs in a dynamic environment. Collaborate with cross-functional teams to manage scope, budget, and timelines while ensuring client satisfaction an...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Reimagine payroll processes by building and managing US and international payroll systems. Own compliance, tax filings, and month-end close while collaborating with teams to ensure accuracy and effici...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Elevate the technical architecture vision and execution across a product portfolio, driving the transition to a scalable, cloud-native SaaS environment while integrating AI, data, and security. Collab...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Business Services

$98K - $163K *

Shape your career by providing Tier III IT Systems support across enterprise technologies. Collaborate on projects, resolve complex challenges, and mentor junior engineers while ensuring operational e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$155K - $200K *

Elevate product management by driving vision, strategy, and execution across digital solutions in clinical development. Collaborate with cross-functional teams to enhance user experience and operation...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team to drive product strategy and execution for public safety software. Collaborate across functions to deliver mission-critical solutions that enhance community safety and support eme...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.