Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
$120K - $145K *
Empower the development of high-quality web interfaces by leading projects, mentoring engineers, and enhancing engineering processes. Collaborate on technical vision while fostering a culture of excel...
Yesterday
$140K - $160K *
Elevate your career by joining a dynamic team as a Data Engineer, owning end-to-end data systems and driving platform modernization. You'll improve data reliability and work closely with cross-functio...
Reposted 4 weeks ago
Sr. Software Development Engineer - National Imagery
$123K - $202K *
Innovate advanced GIS and remote sensing software for defense and intelligence, collaborating with a skilled team to enhance analytical workflows and imagery processing capabilities, while mentoring j...
3 weeks ago
Senior DevOps Engineer (Active Secret Clearance)
$185K - $230K *
Advance your career by ensuring seamless performance of AI systems in diverse environments. Collaborate with customers and teams, automating and maintaining infrastructure for reliability across uncla...
Reposted 5 days ago
$135K - $160K *
Lead the charge in developing a cutting-edge AI product, managing a high-performing team of engineers while ensuring quality, reliability, and speed in delivery. Collaborate closely with Product and D...
2 weeks ago
Senior/Staff DevOps Engineer, Federal
$180K - $240K *
Champion innovation by building and operating secure infrastructures for federal and partner environments, ensuring seamless deployments and reliable operations across diverse cloud and on-premises pl...
5 days ago
Software Engineer, Integrations (US + Calgary)
$140K - $160K *
Accelerate progress at our integration platforms, ensuring scalable, reliable data flows. You'll design, build, and optimize workflows while collaborating across teams to enhance performance and custo...
2 weeks ago
Director of Engineering, Database Excellence
$230K - $345K *
Lead the charge in database excellence to enhance reliability, performance, and sustainability of GitLab's datastores. Shape long-range strategies while collaborating across teams to drive success in...
Reposted yesterday
Principal Software Architect - Emerging Technologies
$175K - $222K *
Engage in architecting high-volume autonomous agent pipelines, ensuring safety, performance, and compliance. Own the generator-verifier architecture and CI/CD processes while setting engineering stand...
6 days ago
Senior Program Manager, Application Security
$125K - $150K *
Lead the charge in transforming enterprise security implementations into measurable success. Drive customer outcomes, manage complex programs, and build trusted relationships with executives to ensure...
2 days ago
$130K - $155K *
Join a team that's redefining data infrastructure by owning and optimizing our data pipelines, warehouse, and modeling layers. Collaborate with cross-functional teams to ensure data integrity and driv...
Reposted 2 weeks ago
Product Engineer- Endpoint Security
$90K - $153K *
Lead the enhancement and administration of enterprise endpoint security technologies, collaborating with cross-functional teams to optimize security processes and improve detection capabilities in a g...
2 weeks ago
Software Engineer III, iOS - Cal AI
$135K - $165K *
Engage with our Cal AI team to enhance user experiences through innovative iOS development. Collaborate, mentor, and implement high-quality features that empower users on their health journeys while f...
2 weeks ago
Lead .NET Engineer with AI tools
$130K - $155K *
Unlock potential by leading the design and development of enterprise applications using C# and .NET, driving modern software practices, and collaborating with cross-functional teams to implement secur...
Reposted 1 month ago
$128K - $165K *
Lead reliability initiatives across complex systems, driving automation and observability. Collaborate with teams to enhance operational outcomes, manage incidents, and mentor engineers, ensuring comp...
4 weeks ago
$145K - $150K *
Lead the charge in developing web-based dissemination tools for external users, collaborating with developers to enhance data visualization and streamline CI/CD processes using modern frameworks and b...
2 weeks ago
Senior Machine Learning Engineer, Fulfillment
$173K - $182K *
Lead the charge in designing and deploying impactful machine learning systems. Collaborate across teams to drive innovation and improve business outcomes in a fast-paced environment, leveraging your e...
6 days ago
$200K - $220K *
Manage and elevate a team of engineers to deliver AI-powered healthcare solutions. Oversee project planning, architecture, and team development while ensuring high-quality outcomes in a fast-paced, re...
Today
Senior Developer - Workforce AI, IT AI COE
$106K - $159K *
Help us build and innovate workforce AI platforms, integrating advanced systems and analytics to enable seamless AI adoption and enhance productivity across the enterprise. Drive measurable impact and...
Reposted 4 weeks ago
Staff Software Development Engineer
$106K - $284K *
Drive innovation by leading the design and development of scalable software solutions, mentoring engineers, and collaborating with cross-functional teams to enhance patient care and clinical technolog...
Yesterday
Staff Software Development Engineer
$106K - $284K *
Lead the charge in designing and delivering secure, scalable microservices that enhance healthcare data exchange. Collaborate with cross-functional teams to ensure compliance and operational excellenc...
Yesterday
Staff Software Development Engineer
$106K - $284K *
Reimagine healthcare technology by leading the development of secure, scalable microservices. Collaborate with cross-functional teams to enhance digital solutions that transform patient experiences an...
1 week ago
Staff Software Development Engineer
$106K - $284K *
Join a team that’s redefining pharmacy and healthcare through innovative digital solutions. As a Staff Software Development Engineer, you'll lead in creating next-generation platforms, ensuring qualit...
Reposted 2 weeks ago
Staff Software Development Engineer
$106K - $284K *
Champion the design and development of scalable applications, integrating AI and data systems. Lead technical strategy, mentor teams, and ensure operational excellence across the technology stack whil...
Reposted 2 weeks ago
Senior Implementation Engineer
$110K - $130K *
Drive enterprise solution implementations by leading requirements analysis, designing scalable architectures, and delivering innovative solutions. Collaborate with teams to ensure quality and manage c...
2 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.