Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$95K - $115K *

Develop and maintain core financial platforms, ensuring reliability and data integrity. Collaborate with cross-functional teams to implement scalable solutions and enhance platform performance in a re...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$121K - $191K *

Join the team to design and develop scalable software solutions for healthcare supply chain transactions. Collaborate with cross-functional partners to enhance the rules engine and deliver high-qualit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $190K *

Lead the design and evolution of scalable data architecture, providing technical leadership across teams to deliver reliable, secure, and cost-effective data solutions while shaping emerging capabilit...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$208K - $250K *

Unlock the potential of enterprise deployment solutions by defining product vision and strategy. Collaborate with cross-functional teams to adapt offerings for compliance-driven environments, ensuring...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $175K *

Engineer your career with a Senior Software Safety Engineer role focused on developing safety-critical autonomous systems. Collaborate with a multi-disciplinary team to enhance software safety process...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $150K *

Pioneer the future of HR technology by leading cross-functional teams to define and deliver innovative solutions in Global Mobility and Talent Management, ensuring alignment across stakeholders and se...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$174K - $220K *

Pioneer significant enhancements in cloud infrastructure, optimizing capacity and performance. Drive cross-functional collaboration to ensure scalability and reliability while shaping best practices...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$173K - $290K *

Champion innovation in product development platforms, driving strategy and execution for AI-first tools that enhance collaboration and efficiency across teams. Lead the evolution of platforms, ensurin...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $170K *

Innovate with AI to enhance HR software. Design and develop scalable web services, lead initiatives, and mentor engineers while focusing on user experience and collaboration in a dynamic environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$99K - $232K *

Pioneer innovative data solutions as a Manager, leading teams to transform raw data into actionable insights, driving business growth through advanced technologies and fostering client relationships w...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$106K - $284K *

Join a dynamic team to design and deliver innovative iOS solutions that enhance customer health experiences. Collaborate across functions, lead technical initiatives, and drive the development of secu...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$107K - $204K *

Drive innovative cybersecurity solutions for connected systems by leading research and development efforts. Collaborate with multidisciplinary teams to tackle complex challenges and enhance the securi...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$187K - $234K *

Empower the Integrations team to scale impact by leading third-party integrations, creating reusable capabilities, and fostering a collaborative culture that drives effective delivery and continuous i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$112K - $155K *

Accelerate progress at a leading tech firm by developing scalable, cloud-native APIs. Collaborate with cross-functional teams to enhance core offerings and lead discussions on software architecture, e...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$138K - $230K *

Join a dynamic team to deliver professional services, guiding public sector clients in adopting GitLab through installations, migrations, and training. Balance technical expertise with project managem...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$253K - $298K *

Lead transformative initiatives by leveraging AI and engineering excellence to redefine compliance operations. This role focuses on building high-performing teams and designing scalable solutions that...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$217K - $303K *

Innovate with us to lead a high-performing engineering team, shaping a scalable AI-powered knowledge graph platform that enhances data quality and drives impactful user experiences across multiple app...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Media

$118K - $178K *

Empower your career by designing and enhancing enterprise AI platforms. Collaborate with cross-functional teams to deliver secure, scalable solutions while driving operational excellence and innovatio...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Accelerate progress at a high-growth infrastructure team managing Kubernetes platforms across multiple clouds. You'll enhance GPU resource efficiency and ensure system reliability while collaborating...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $180K *

Drive innovative electrical design solutions for high-density compute environments. Collaborate across teams to ensure compliance with industry standards while mentoring junior engineers. Make a signi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $160K *

Drive the development of critical enterprise applications for defense personnel, utilizing Java, Spring Boot, and Angular. Collaborate in an agile team to enhance program and financial management tool...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $92K *

Help us design and implement innovative software solutions that meet business needs. Collaborate with cross-functional teams to deliver scalable, secure applications while staying current with emergin...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $160K *

Drive innovation by building scalable data integration solutions, collaborating with cross-functional teams to enhance healthcare technology. Ensure data quality and security while optimizing performa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $251K *

Join a dynamic software development team to innovate cybersecurity solutions for connected systems. Lead research, collaborate with engineers, and tackle complex challenges to enhance security for cri...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $170K *

Lead mobile development efforts, mentoring teams and driving architecture decisions. Collaborate with cross-functional teams to deliver high-quality iOS and Android applications, ensuring alignment wi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.