Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$168K - $285K *

Elevate the future of software planning by leading a team that integrates human and AI collaboration. Shape product direction, connect work to business priorities, and drive strategic decisions in a d...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$74K - $112K *

Engineer innovative autonomy solutions for agricultural equipment, tackling complex software challenges from concept to production while ensuring quality and continuous improvement in guidance systems...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Champion data excellence by designing and optimizing scalable data platforms. Collaborate with cross-functional teams to enhance performance and drive innovation in data processing, ensuring alignment...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$184K - $356K *

Elevate the future of autonomous software systems by building and optimizing AI agent evaluation frameworks, enhancing usability, reliability, and performance with a collaborative engineering team ded...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$117K - $157K *

Join a team that's transforming enterprise AI solutions through innovative design and deployment. Leverage your expertise to build secure, scalable AI platforms that enhance business processes and dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$118K - $178K *

Lead cross-functional teams to design, develop, and enhance AI solutions, ensuring production readiness and security while optimizing developer experience and cost efficiency across enterprise capabil...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$164K - $284K *

Lead and inspire a high-performing software engineering team, driving product innovation and technical excellence while fostering a culture of collaboration and continuous improvement in a fully remot...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $220K *

Champion the evolution of scalable infrastructure in a multi-cloud environment, collaborating with engineering teams to enhance reliability and performance for AI-driven healthcare solutions...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Champion innovative data solutions by designing and maintaining robust data pipelines across Azure and Microsoft Fabric, ensuring high-quality data delivery and governance while leading engineering in...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$121K - $142K *

Elevate automation in software engineering by building AI-driven tools and systems. Collaborate with a focused team to enhance reliability and speed in package and image management, shaping the future...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a team that's shaping the future of software development by leading complex projects, mentoring talent, and driving innovative solutions that align with business goals while ensuring optimal perf...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $175K *

Transform your career as a Senior Software Engineer, leading cross-functional teams to design and implement Java Spring Boot microservices and RESTful APIs on AWS, driving innovation and operational e...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Unlock potential by leading complex engineering initiatives across Microsoft 365 collaboration services, ensuring secure, reliable solutions while mentoring engineers and enhancing platform health thr...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$140K - $160K *

Lead the development of a robust web application by designing, coding, and testing software while mentoring junior engineers. Collaborate on process improvements and ensure compliance with industry re...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$222K - $314K *

Accelerate progress at a pivotal backend engineering role, enhancing critical systems and data integrity while driving innovation through high-stakes projects within an empowered team focused on scala...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$170K - $210K *

Engage in client development and system architecture while leading a team to enhance client satisfaction. Collaborate on solutions, mentor staff, and drive growth through effective communication and s...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Drive impactful software solutions by embedding with clients, transforming ambiguous needs into deployable features across secure environments. Collaborate closely with users and stakeholders to deliv...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$86K - $165K *

Advance your career by developing core embedded Linux components for avionics systems. Collaborate globally to influence architecture and support diverse airborne platforms, ensuring robust, secure so...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$115K - $145K *

Elevate your career by designing and optimizing data pipelines that empower analytics and AI solutions. Collaborate with cross-functional teams to ensure data integrity and governance while mentoring...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$225K - $265K *

Lead and mentor a diverse team of backend engineers in EDR remediation, transforming insights into actionable product capabilities while managing scope and fostering collaboration across engineering t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $135K *

Drive the evolution of critical DNS infrastructure, ensuring operational excellence, collaborating across teams, and enhancing production services through automation and API development...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$116K - $156K *

Engineer innovative platforms and tooling for AI agents, enhancing the development experience. Collaborate across teams to ensure secure, efficient, and scalable solutions that empower engineers to bu...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $183K *

Innovate the future of healthcare technology by developing scalable applications that streamline specialty prescriptions. Collaborate with a skilled team to enhance user experience and drive efficienc...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Drive the development and deployment of a cutting-edge control plane for identity and credential management, ensuring reliability and security in customer-hosted environments while collaborating with...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$74K - $112K *

Empower the development of innovative software solutions for embedded agricultural systems, collaborating with cross-functional teams to enhance Precision Ag technologies and deliver high-quality, cus...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.