Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$162K - $258K *

Drive the design and implementation of cutting-edge GenAI solutions, leading the development of LLM capabilities and ML pipelines to enhance insurance workflows and deliver impactful outcomes for cust...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$124K - $170K *

Lead the charge in innovative software solutions for healthcare, collaborating with diverse teams to enhance patient care and meet customer needs through cutting-edge technology and creative problem-s...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $240K *

Transform the future of distributed systems by designing and building robust platform components. Collaborate with teams to ensure reliability and scalability in mission-critical environments, driving...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Join a team that's shaping the future of AI engineering by leading a dynamic group of engineers and Technical Leads. Drive workforce strategy, enhance team capabilities, and ensure sustainable deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$242K - $275K *

Lead the charge in developing and deploying robust containerized software, manage CI/CD workflows, and grow a cohesive engineering team to enhance customer security operations and software delivery ac...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$164K - $240K *

Collaborate with cross-functional teams to build AI infrastructure, ensure reliability and security, and guide technical direction while fostering engineer development. Lead innovative projects that e...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$144K - $195K *

Join a team that's transforming the legal experience by developing innovative web applications. Collaborate with diverse teams, mentor junior engineers, and tackle complex challenges in a dynamic, agi...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$180K - $240K *

Unlock innovative solutions as you build full-stack applications for federal partners, focusing on user experience, security, and seamless integrations. Collaborate with engineers and product teams to...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$466K - $500K+*

Join a team that's shaping the future of AI by designing and building scalable platforms for large-scale machine learning model training, enhancing performance, and creating user-friendly experiences...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$130K - $170K *

Lead the evolution of our design system by building accessible, reusable components and collaborating with cross-functional teams to enhance user experiences and streamline adoption across products...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Finance & Insurance

$179K - $341K *

Join a dynamic team to enhance C#/.NET integration for Unity Engine, driving performance and reliability. Collaborate with experts to deliver key technical solutions and advocate best practices for de...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $170K *

Join a team that's transforming digital services for Veterans by leading a skilled engineering group. You'll balance hands-on technical leadership with mentoring, driving the development of scalable J...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$138K - $165K *

Transform AI capabilities by building robust SDKs and infrastructure. Collaborate with product teams to enhance agent workflows, ensuring reliability and performance while driving innovation in AI exp...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$153K - $213K *

Champion the development of a key platform, driving strategy, success metrics, and technical depth while collaborating across teams to deliver impactful solutions that meet customer needs and enhance...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the development of innovative Provider Onboarding solutions, architecting robust systems and mentoring engineers to enhance mental healthcare access. Drive product implementations and build scala...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in transforming patient engagement by integrating booking into our core product. Drive innovative experiments and optimize multi-channel outreach to ensure underserved communities rece...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $165K *

Join a dynamic team as you lead the design and development of complex software systems. Drive technical direction, mentor peers, and ensure high-quality, scalable solutions that align with business go...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$284K - $385K *

Shape the future of technology by tackling complex challenges and driving AI adoption. Collaborate across teams to define long-term strategies, enhance customer experiences, and influence product dire...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$130K - $160K *

Create seamless user experiences by developing robust APIs and integrating third-party software. Collaborate with teams to design systems that prioritize performance and maintainability while tackling...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $204K *

Unlock innovation by leading software engineering efforts, focusing on design, development, and verification of complex avionics systems. Collaborate with cross-functional teams to enhance product qua...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$130K - $170K *

Champion innovative solutions by designing and implementing core platform features, driving the transition to microservices, and collaborating across teams to enhance scalability and flexibility in Io...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $170K *

Lead the development of scalable systems, balancing individual contributions with technical guidance. Collaborate across teams to tackle complex engineering challenges in security and AI, while evolvi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Shape the future of networking by designing and implementing advanced SDN orchestration systems for high-performance, isolated networking in distributed computing environments, enabling seamless acces...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$172K - $215K *

Advance your career by leading software development initiatives, driving architecture design, and optimizing performance in a collaborative environment. Engage with cross-functional teams to deliver s...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$208K - $234K *

Drive the growth of Honeycomb Private Cloud by leading a senior engineering team, enhancing customer relationships, and ensuring operational excellence across multiple engineering domains. Collaborate...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.