Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Mobile Implementation Specialist
$96K - $148K *
Unlock the potential of government partnerships by managing client projects across the US. Support project design, training, and implementation, ensuring optimal client experiences and delivering succ...
Reposted 6 days ago
Staff Application Security Engineer
$225K - $281K *
Shape the future of application security by leading strategy and initiatives across teams. Drive secure design and standards, mentor engineers, and tackle complex security challenges in a collaborativ...
6 days ago
Principal Enterprise Architect
$177K - $290K *
Transform enterprise architecture by defining and implementing core frameworks, driving AI integration, and building consensus across teams. Lead the development of standards and strategies to support...
3 weeks ago
$113K - $188K *
Join a dynamic team to design and develop high-performance ETL solutions, integrating data from diverse sources. Collaborate with cross-functional teams to optimize data workflows and ensure complianc...
1 week ago
$95K - $115K *
Elevate your career by driving the design and deployment of AVEVA MES projects. Collaborate with cross-functional teams to ensure quality solutions, mentor junior engineers, and enhance user adoption...
1 week ago
$95K - $115K *
Champion compliance and security excellence by driving NIST 800-53 and FedRAMP initiatives. Partner with clients to ensure federal authorization, author vital documents, and manage multiple A&A projec...
Reposted 1 week ago
$170K - $210K *
Engage in client development and system architecture while leading a team to enhance client satisfaction. Collaborate on solutions, mentor staff, and drive growth through effective communication and s...
1 week ago
$97K - $126K *
Transform marketing strategies by connecting buyer needs with sales execution. Lead integrated campaigns, enhance customer engagement, and drive growth through innovative go-to-market planning and col...
1 week ago
$150K - $180K *
Engage as a hands-on architect to design and implement AI solutions, ensuring alignment with enterprise standards and governance. Collaborate with teams to accelerate adoption and maintain best practi...
3 weeks ago
$111K - $150K *
Join a team that's advancing renewable energy solutions through expert power system analysis. Lead complex studies, collaborate with cross-functional teams, and drive innovative engineering practices...
2 weeks ago
Senior Director, Full-stack Engineer (Remote-Eligible) - Global Payment Network
$286K - $326K *
Empower high-performing teams to innovate banking solutions in the cloud. Drive technical strategy, coach engineers, and enhance delivery for a resilient, scalable platform. Foster a culture of contin...
3 weeks ago
$120K - $145K *
Transform security engineering practices by building resilient systems that enhance and automate security workflows, ensuring smooth operation across multiple environments while integrating AI-assiste...
Reposted today
$104K - $166K *
Drive modernization efforts in America's airspace by ensuring accurate software installations and configurations for the FAA's Terminal Flight Data Manager program. Collaborate with teams to resolve t...
3 days ago
Staff Software Engineer, Mobile QA
$218K - $286K *
Unlock potential by leading the mobile QA infrastructure for our greenfield app project. Drive automation, establish quality standards, and partner cross-functionally to ensure excellence in product d...
3 weeks ago
$153K - $186K *
Advance your career by driving the design and architecture of enterprise-grade software solutions. Collaborate with teams to deliver secure, scalable applications leveraging innovative AI technologies...
1 month ago
Electrical Engineering Consultant 2 - Nuclear
$145K - $222K *
Lead and mentor a team in tackling complex electrical engineering projects, ensuring successful delivery and client satisfaction while coordinating multi-discipline efforts in the nuclear power sector...
1 week ago
Solutions Architect, Public Sector - East
$125K - $150K *
Unlock potential by providing technical expertise to government customers, guiding them in using GitLab's solutions for impactful business outcomes. Collaborate with sales and stakeholders to ensure e...
Reposted 2 weeks ago
$117K - $201K *
Unlock potential by leading AI-driven endpoint management, enhancing security and user experience while transitioning to autonomous operations. Collaborate with cross-functional teams to innovate and...
Today
$120K - $140K *
Unlock potential by designing and deploying cutting-edge AI solutions that enhance enterprise operations. Collaborate across teams to create scalable, secure applications that drive efficiency and inn...
3 days ago
$90K - $114K *
Transform customer experiences by bridging technical solutions and business outcomes. Collaborate with cross-functional teams to deliver tailored solutions that enhance people operations and culture...
2 weeks ago
Senior Customer Success Manager
$120K - $130K *
Accelerate your career by managing a portfolio of mid-market accounts, ensuring customer success through strategic engagement, relationship building, and AI-driven insights. Drive measurable outcomes...
2 weeks ago
Senior Technical Product Marketing Manager, Edge (SMM194)
$130K - $155K *
Lead the charge in developing and executing go-to-market strategies for innovative AI products in the defense sector, ensuring effective positioning, messaging, and adoption throughout the product lif...
1 week ago
$90K - $110K *
Empower financial decision-making by leading analysis, forecasting, and budgeting. Collaborate with cross-functional teams to deliver insights and enhance reporting efficiency using advanced tools and...
1 week ago
21GRAMS- Senior Technology Lead
$119K - $140K *
Shape the future of technology in healthcare by leading development efforts, leveraging AI tools, and ensuring high-quality digital deliverables across multiple platforms. Collaborate with creative te...
Reposted 6 days ago
$73K - $102K *
Drive the design and implementation of innovative CCaaS solutions, collaborating with cross-functional teams to enhance software applications and ensure system reliability while maintaining high-quali...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.