Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$101K - $206K *

Join a team that's redefining AI product development by leading high-performing engineering teams. Drive innovation and collaboration across functions to deliver scalable AI solutions, while fostering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Develop and enhance automated provisioning systems to efficiently onboard high volumes of servers. Collaborate with cross-functional teams to ensure smooth integration and process optimization, direct...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$90K - $145K *

Unlock your potential by designing CI/CD pipelines and automating processes. Collaborate with teams to enhance development efficiency while ensuring system compliance and security across AWS and Azure...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$148K - $215K *

Reimagine the future of financial engagement by leading innovative software development. Engage in full-stack responsibilities, collaborating across teams to enhance product experiences for educationa...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$179K - $232K *

Drive AI-assisted workflows to transform design into production code, collaborating with cross-functional teams to enhance Thumbprint’s design system and tooling. Contribute to a greenfield project th...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$162K - $290K *

Contribute to building cutting-edge software systems that harness AI to solve real-world operational challenges. Drive technical strategy, collaborate across teams, and develop full-stack solutions in...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Pioneer innovative software solutions for defense programs by leveraging your expertise in C#, .NET, and SQL Server. Collaborate with cross-functional teams to ensure secure, compliant, and high-quali...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Lead the charge in software innovation while mentoring a high-performing engineering team. Drive technical solutions and ensure project success through hands-on involvement, fostering a culture of con...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $185K *

Invent the future of fintech by leading the development of next-gen payment systems. Utilize your expertise to mentor others and enhance our platform, driving innovation and maintaining high standards...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$136K - $160K *

Contribute to innovative software solutions by collaborating with a dynamic team, solving customer challenges, and enhancing product functionality through effective coding and testing practices...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's shaping the future of energy solutions by designing and building robust backend services and APIs, optimizing AI-native development, and driving innovation in renewable energy portf...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Architect AI-driven solutions that automate workflows across teams, enhancing efficiency and productivity. Collaborate with diverse departments to design, deploy, and iterate on intelligent agents, sh...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Grow a dynamic team driving OpenRouter’s provider ecosystem, managing innovations across diverse models and endpoints, ensuring quality and efficiency in inference services for millions of requests da...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $171K *

Optimize multi-cloud access control and security tools. Collaborate with teams to design and implement automated solutions, ensuring secure developer workflows across AWS, Azure, and GCP while enhanci...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$150K - $200K *

Transform complex engineering projects by leading a team of specialists in BAS and EPMS designs for critical data center sectors, ensuring high quality and timely deliverables while mentoring talent a...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$185K - $255K *

Elevate data management by designing scalable storage solutions and ingestion pipelines. Lead technical direction, optimize performance, and ensure reliable access to historical data for product teams...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in engineering and securing infrastructure while ensuring compliance with federal cybersecurity standards. Collaborate cross-functionally to develop robust solutions that protect sensi...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$179K - $224K *

Unlock innovative solutions as you guide software engineering teams to navigate complexities and enhance integrations while mentoring diverse talents in a collaborative environment...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Innovate and develop complex applications for federal clients, collaborating with teams to ensure high-quality solutions. Utilize modern technologies and best practices to enhance user experience and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$130K - $260K *

Shape the future of fleet navigation by owning end-to-end projects, delivering high-quality software across platforms, and collaborating cross-functionally to enhance user experiences in complex envir...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Innovate with us as a Senior Software Engineer, driving core feature development and automation across the stack. Collaborate with diverse teams to enhance scalability and performance in a dynamic, mi...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Drive the evolution of product and engineering systems by managing platforms like Jira and Aha!. Collaborate cross-functionally to enhance workflows, integrations, and reporting, ensuring tools align...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $170K *

Champion innovative solutions by designing and implementing core platform features, driving the transition to microservices, and collaborating across teams to enhance scalability and flexibility in Io...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$159K - $254K *

Join a dynamic team to design and deliver innovative Android system applications, enhancing device management and user experience. Collaborate across functions to build scalable solutions that empower...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Take ownership of IT infrastructure and security operations, driving the migration to a Nutanix-based IaaS environment. Collaborate with teams to enhance security, compliance, and automation, utilizin...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.