Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$120K - $130K *

Elevate your career by leading electrical engineering for complex commercial projects. Drive innovative design solutions, mentor junior engineers, and ensure project success from concept to completion...

1 week ago

  •   5 - 7 years exp.  •   Staffing

$135K - $160K *

Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Drive mobile engineering excellence across diverse product teams, ensuring strategic direction, fostering collaboration, and enhancing delivery. Lead managers, shape architecture, and cultivate a prod...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$60K - $152K *

Engage with clients to deliver exceptional software support for MQ on mainframe systems. Collaborate across teams to ensure timely installations, upgrades, and migrations while adhering to best practi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Oversee medium complexity projects, leveraging technical expertise and leadership skills to drive successful program milestones and continuous improvement while managing risks and collaborating with c...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $175K *

Elevate your career by leading innovative solar and energy storage projects. Drive technical excellence, mentor teams, and collaborate with stakeholders to shape sustainable energy solutions across No...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$120K - $225K *

Engage in mission-critical software development, leveraging Java and modern frameworks. Collaborate with cross-functional teams to ensure high standards throughout the development lifecycle while main...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$96K - $151K *

Join a team that's transforming healthcare by developing analytic products from clinical data. Collaborate in an agile environment to deliver insights that enhance efficacy and drive innovation in the...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate software solutions by managing their lifecycle, from planning to launch. Drive strategic product development, market analysis, and cross-functional collaboration to enhance customer satisfacti...

6 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$132K - $261K *

Deliver innovative digital employee experience solutions by leading enterprise-wide initiatives, providing strategic guidance, and enhancing workplace technologies to boost productivity and operationa...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$132K - $261K *

Transform employee experiences by leading digital initiatives, providing strategic guidance, and implementing scalable solutions that enhance productivity and operational efficiency across enterprise...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$130K - $155K *

Lead data architecture initiatives by optimizing serverless data pipelines and enhancing analytics capabilities through AWS services like SageMaker and Glue. Collaborate on data lakes and AI integrati...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Pioneer advancements in polymer science by designing experiments, analyzing data, and mentoring junior scientists. Collaborate across teams to enhance membrane formulation and manufacturing processes...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $180K *

Drive the modernization of Veterans Benefits Administration claims processing by designing and optimizing scalable data pipelines and solutions, ensuring efficient data integration and analytics for i...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$145K - $209K *

Accelerate progress at the intersection of machine learning and software engineering, driving innovative solutions for ticketing optimization, personalization, and fraud detection. Collaborate across...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $180K *

Transform AI infrastructure by designing and maintaining production-grade systems across multiple cloud providers. Engage in hands-on architecture decisions, ensuring reliability, security, and automa...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$117K - $164K *

Transform your career by leading Identity and Access Management initiatives, enhancing security protocols, and driving automation in a dynamic IT environment. Collaborate with cross-functional teams t...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Champion the delivery of innovative data solutions, leading cross-functional teams to modernize platforms and drive AI integration. Ensure project success through effective management of scope, qualit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$116K - $125K *

Elevate cybersecurity measures by designing and implementing robust controls for enterprise applications and infrastructure. Collaborate with cross-functional teams to ensure compliance with federal s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$141K - $165K *

Unlock potential by leading the design and development of critical backend services using C# and .NET. Drive engineering quality, resolve complex production issues, and establish best practices for re...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$128K - $165K *

Lead reliability initiatives across complex systems, driving automation and observability. Collaborate with teams to enhance operational outcomes, manage incidents, and mentor engineers, ensuring comp...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Transform your career by joining a dynamic team of Application Developers. Lead the design and development of enterprise-level applications, utilizing cutting-edge technologies to drive innovation and...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $212K *

Pioneer innovative IAM strategies to enhance security across cloud and on-premise infrastructures. Collaborate with cross-functional teams to implement robust identity governance and access management...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $160K *

Join our U.S. Government Support Engineering team to tackle complex technical challenges in secure environments. Leverage your Linux expertise and customer support skills to enhance GitLab's performan...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $150K *

Advance your career by leading product strategy for supply chain orchestration. Drive technical decisions, collaborate with cross-functional teams, and leverage AI to enhance workflows, ensuring measu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.