Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$138K - $230K *

Join a dynamic team to deliver professional services, guiding public sector clients in adopting GitLab through installations, migrations, and training. Balance technical expertise with project managem...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$90K - $189K *

Empower our team as a Product Owner, leading strategic execution and collaboration with engineering to define features, manage backlogs, and ensure successful delivery of mission-critical software sol...

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$195K - $325K *

Join a team that's shaping the future of AI in healthcare by leading multi-year strategies, resolving complex technical challenges, and influencing executive decisions across the organization to ensur...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Shape the future of technology resiliency by coordinating change governance, managing incident support, and ensuring operational excellence across critical services. Collaborate with stakeholders to e...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform your career as you design and secure automated delivery pipelines, ensuring streamlined deployment and compliance while collaborating with cross-functional teams to enhance cloud infrastruct...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Unlock AI-driven engineering transformation by collaborating with clients to enhance SDLC processes. Drive measurable improvements in delivery speed and quality through innovative solutions and hands...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Engage in the design and management of enterprise endpoint technologies, ensuring security and efficiency across over 1,000 devices. Collaborate with cross-functional teams to enhance endpoint perform...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $189K *

Contribute to critical government missions as a Release Train Engineer, facilitating Agile Release Train events, coaching teams, and driving continuous improvement to deliver value using cutting-edge...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$75K - $100K *

Empower innovation by developing secure web applications as a Full Stack Developer. Work collaboratively across frontend and backend components, enhancing functionalities while supporting mission-driv...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$155K - $165K *

Develop a cutting-edge data ecosystem as a Senior Data Engineer, enhancing analytics, reporting, and machine learning. Collaborate with cross-functional teams to create efficient pipelines and accessi...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$160K - $220K *

Explore your career by driving AI-led software delivery transformations. Collaborate with cross-functional teams to enhance SDLC processes, leveraging cutting-edge tools and methodologies to achieve m...

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$110K - $204K *

Execute a collaborative approach to develop and validate Cyber solutions, conducting risk assessments and coordinating with architects to ensure compliance with security requirements throughout the li...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$112K - $130K *

Engineer innovative web applications and lead development teams to enhance software solutions. Collaborate with stakeholders to deliver high-quality products while mentoring developers and ensuring pr...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $125K *

Transform data analytics initiatives by leading multiple projects, engaging stakeholders, and driving solutions from inception to delivery. Collaborate with technical teams to ensure alignment with mi...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$250K - $300K *

Shape the future of AI-driven platforms by designing scalable applications and intelligent workflows. Lead initiatives that enhance operational efficiency and enable real-time insights, while mentorin...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$135K - $251K *

Empower innovation by leading cross-functional teams to design and implement advanced system architectures. Collaborate with stakeholders to deliver solutions that meet evolving digital transformation...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$92K - $110K *

Elevate packaging solutions by developing, testing, and launching innovative designs. Collaborate with cross-functional teams to enhance quality, efficiency, and sustainability in manufacturing proces...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Elevate your career by leading automation projects from concept to execution. Collaborate with cross-functional teams to design and enhance manufacturing systems, driving efficiency and innovation acr...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$105K - $234K *

Lead the design and delivery of complex platform capabilities, enhancing reliability and security while mentoring engineers. Collaborate across teams to drive technical excellence and implement AI-ass...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$202K - $253K *

Elevate your leadership as you drive engineering excellence, overseeing multiple squads from prototype to production. Shape the roadmap, empower teams, and ensure quality delivery while staying techni...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$190K - $228K *

Lead the charge in shaping enterprise network architecture and modernization strategies. Provide technical guidance and design expertise to enhance security, scalability, and performance for a DoD age...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $228K *

Transform enterprise network architecture by providing strategic guidance and innovative design solutions. Lead a team in enhancing network security, scalability, and performance for a DoD agency's WA...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$140K - $173K *

Transform data acquisition processes by leading the development of high-performance ingestion pipelines. Collaborate across teams to ensure data quality, reliability, and security while shaping the fu...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$93K - $147K *

Join a dynamic team to enhance and modernize applications, leveraging AI and containerization. Lead system improvements, mentor peers, and ensure high-quality software delivery across diverse environm...

Today

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.