Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$80K - $95K *

Unlock automation potential by leading projects from concept to execution, enhancing production efficiency through innovative solutions and hands-on troubleshooting in a dynamic manufacturing environm...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$128K - $160K *

Lead the charge in delivering innovative AI and automation solutions, translating complex business needs into technical designs. Collaborate across teams to enhance productivity and drive continuous i...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Innovate the future of architectural strategy by leading technical direction, fostering collaboration across teams, and driving scalable solutions that align with business goals while mentoring senior...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team to drive technical vision and operational excellence in cloud-native platforms. Lead engineering efforts, champion security practices, and empower talent while ensuring system stab...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by leading the design and implementation of cutting-edge test automation solutions, leveraging JavaScript and Python to enhance scalability, quality, and speed in the software develop...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$151K - $309K *

Empower the development of innovative features on a high-traffic Orders platform, collaborating across teams to enhance architecture and tooling, ensuring efficient processing for over 1 billion order...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$116K - $165K *

Lead the design and integration of marine electrical systems for commercial and governmental vessels. Ensure compliance with regulatory standards while managing technical responsibilities for shipboar...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Join a team that's leading the modernization of a legacy system. Drive architectural decisions, enhance engineering practices, and foster a culture of innovation while ensuring reliable delivery and c...

Pennsylvania, USRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Reimagine your career by leading engineering modernization efforts, guiding a talented team through incremental technology transitions, and enhancing product delivery while ensuring quality and compli...

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$138K - $165K *

Transform the future of pharmacy operations by leading the development of scalable, reliable front-end solutions. Collaborate with cross-functional teams to enhance user experiences and drive technica...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Optimize verification strategies and lead hands-on testing to enhance product reliability. Collaborate across engineering disciplines to translate requirements into effective test methods, driving imp...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$193K - $285K *

Empower the Security Engineering team by leading the technical vision for platform hardening across global operations, ensuring a secure and resilient delivery network through innovative practices and...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$139K - $203K *

Architect and develop high-performance backend services, leading complex initiatives and driving technical design decisions to enhance Splunk's enterprise observability and security platform while col...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$95K - $115K *

Shape the future of SOC designs by innovating RTL-based blocks, enhancing performance and reliability while engaging in modules' design, simulation, and verification processes for cutting-edge technol...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Transform the future of manufacturing by leading AI and Smart Manufacturing initiatives. Collaborate with teams to create impactful solutions, validate business value, and drive digital transformation...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive innovation by embedding with manufacturing teams to translate AI and Smart Manufacturing opportunities into actionable solutions, ensuring rapid delivery and alignment with global product strate...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $104K *

Elevate your career by leading innovative electrical engineering projects. Manage complex designs for diverse sectors, mentor junior staff, and contribute to sustainable initiatives while ensuring qua...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$209K - $275K *

Lead complex technical solutions as a Cisco Splunk Solutions Engineer, driving customer success through deep expertise and innovative architecture. Collaborate with teams to influence product directio...

2 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$202K - $257K *

Empower growth by identifying opportunities and aligning technical strategies with customer goals. Lead solution discussions with executives, drive innovation, and mentor teams to enhance knowledge an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Champion innovative product development in power connectors and cable assemblies. Lead cross-functional teams, drive technical excellence, and mentor engineering talent to deliver high-quality, cost-e...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $155K *

Drive innovative machine learning solutions by designing, implementing, and optimizing systems that enhance user experiences across diverse platforms. Collaborate with a dynamic team to deliver impact...

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $128K *

Champion user interface development and API integration for a federal environmental platform, ensuring accessibility compliance and enhancing data access for regulatory consultations. Collaborate with...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$290K - $340K *

Lead and inspire engineering teams to develop cutting-edge web and AI security solutions. Drive strategy, execution, and organizational health while fostering a culture of innovation and accountabilit...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Lead and innovate within a high-impact engineering team, driving automation and transparency in customer assessments. Foster a culture of accountability while collaborating cross-functionally to deliv...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$92K - $110K *

Empower your career by driving the design and maintenance of robust data solutions, optimizing pipelines, and collaborating with cross-functional teams to ensure data quality and support strategic dec...

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.