Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.
Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.
Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.
Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.
Lead AI Engineer with semantic web tech
$150K - $180K *
Shape the future of semantic technologies by guiding teams in architecting scalable data solutions. Collaborate across functions to define ontologies and drive enterprise-wide data strategy while ment...
4 weeks ago
Site Reliability Engineering Team Lead (Principal SRE)
$150K - $180K *
Unlock potential by leading our Site Reliability Engineering team, ensuring the reliability and performance of our cloud-native platform. Drive technical excellence, cultivate a high-performance cultu...
Reposted 4 weeks ago
Lead Embedded Software Engineer
$110K - $130K *
Accelerate progress at the forefront of embedded software development, driving innovation in optical networking. Collaborate with cross-functional teams to enhance product performance and deliver cutt...
1 week ago
$75K - $100K *
Drive operational excellence by managing maintenance and field service projects, ensuring timely delivery and compliance with safety standards while collaborating with cross-functional teams to enhanc...
Today
Staff Software Engineer, iOS Platform
$217K - $303K *
Innovate the future of iOS development by architecting scalable solutions for Reddit's mobile app. Lead technical direction, mentor engineers, and enhance developer efficiency to support 100M+ DAUs wh...
1 week ago
$120K - $145K *
Lead the Validation and Process Engineering teams to ensure compliance and efficiency in pharmaceutical manufacturing. Oversee equipment validation, project management, and cross-department collaborat...
6 days ago
Senior to Staff Security Engineer / DevSecOps / IAM
$145K - $175K *
Elevate security initiatives by leading IAM and cloud security efforts in a dynamic, remote environment. Collaborate with engineering teams to enhance application security and drive modernization acro...
Reposted today
Staff Software Development Engineer
$106K - $284K *
Reimagine healthcare technology by leading the development of secure, scalable microservices. Collaborate with cross-functional teams to enhance digital solutions that transform patient experiences an...
5 days ago
Staff Software Development Engineer
$106K - $284K *
Join a team that’s redefining pharmacy and healthcare through innovative digital solutions. As a Staff Software Development Engineer, you'll lead in creating next-generation platforms, ensuring qualit...
Reposted 1 week ago
Staff Software Development Engineer
$106K - $284K *
Champion the design and development of scalable applications, integrating AI and data systems. Lead technical strategy, mentor teams, and ensure operational excellence across the technology stack whil...
Reposted 1 week ago
Staff Software Development Engineer
$106K - $284K *
Reimagine application development by leading architecture and scaling core systems. Drive AI integration, mentor teams, and ensure operational excellence across full-stack technologies while deliverin...
Reposted 1 week ago
Lead Software Development Engineer in Test
$165K - $185K *
Accelerate progress at the forefront of test automation, driving quality and performance through innovative strategies and frameworks. Collaborate within an agile team to enhance product scalability a...
Reposted 1 week ago
Senior Manager Software Engineering
$128K - $252K *
Lead the charge in building and managing high-performing software engineering teams. Drive innovation, optimize processes, and deliver high-quality applications while fostering a culture of excellence...
3 weeks ago
SME Software Developer - REMOTE
$114K - $252K *
Unlock potential by leading software development initiatives, ensuring system integration, and guiding teams through agile methodologies to deliver high-quality solutions that meet customer requiremen...
4 days ago
Research Engineer (AI + Sports)
$110K - $130K *
Lead cutting-edge AI research in video analysis and game analytics, transforming sports experiences for fans. Collaborate with academic experts to innovate, publish, and bridge the gap between researc...
Reposted 5 days ago
Application Development Engineer
$95K - $115K *
Elevate your career by driving innovative application development in engineered materials. Collaborate across teams to lead R&D projects, enhance product capabilities, and support market growth in bui...
Reposted 3 days ago
Senior Implementation Engineer
$160K *
Drive enterprise-level implementations of phishing-resistant authentication solutions, leading technical deployments and integrations across various identity platforms while ensuring customer success...
Yesterday
Lead Software Engineer, Dynamics & Power Platform
$110K - $130K *
Elevate enterprise solutions by leading the design and development of scalable applications using Microsoft Dynamics 365 and Power Platform. Drive engineering excellence while mentoring a team to ensu...
Today
Principal Engineer, System Performance Analytics
$200K - $275K *
Lead the development of off-board AI evaluation frameworks to optimize safety and performance for autonomous vehicles. Collaborate with cross-functional teams to design scalable systems and enhance di...
Reposted 3 days ago
$120K - $145K *
Join a dynamic team to build and automate security controls across our infrastructure. You'll manage host hardening, vulnerability assessments, and compliance, leveraging AI tools to enhance security...
4 weeks ago
Staff Backend Engineer, Connect (API Platform)
$186K - $242K *
Empower innovation at a rapidly growing team, leading API architecture and integrations. Collaborate across teams to enhance platform capabilities while mentoring engineers and ensuring system reliabi...
2 weeks ago
Senior DevOps Engineer - ServiceNow Platform Team
$109K - $141K *
Lead the charge in delivering innovative ServiceNow SPM solutions, collaborating with cross-functional teams to enhance product capabilities and drive operational excellence while ensuring adherence t...
1 week ago
$110K - $130K *
Partner with us to bridge technical solutions and customer needs in a dynamic, cross-functional role. Utilize your expertise to drive adoption of AI agents, influencing product roadmaps and enhancing...
Reposted 3 weeks ago
$120K - $144K *
Lead the charge in designing and implementing advanced building automation systems for critical infrastructure projects, ensuring seamless integration and optimal performance while managing teams and...
2 weeks ago
$110K - $130K *
Transform cloud services by providing expert guidance on secure architecture, risk management, and agile workflows. Mentor teams and enhance collaboration while ensuring compliance with federal standa...
1 week ago
What types of $100K+ jobs can I find in Pennsylvania?
Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.
Are these Pennsylvania jobs vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.
Can I find remote or hybrid jobs in Pennsylvania?
Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.