Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$240K - $330K *

Innovate by leading a high-performing team to optimize data pipelines for perception modeling. Collaborate with ML engineers to enhance workflows and drive technical excellence while aligning team goa...

1 week ago

  •   5 - 7 years exp.  •   Transportation

$240K - $330K *

Join a team that's shaping the future of machine learning by leading a high-performing group dedicated to optimizing data pipelines and enhancing perception modeling. Drive innovation and collaboratio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$184K - $356K *

Drive the development and automation of reliable, scalable AI services across diverse cloud environments, ensuring optimal performance and operational safety for production workloads and distributed s...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Drive the technical design and delivery of innovative AI agent solutions, leading a team to ensure operational readiness and quality. Collaborate with stakeholders to define requirements and guide eng...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$86K - $198K *

Unlock your potential by leveraging cloud technologies to modernize IT infrastructures. Collaborate with a skilled team to support national security initiatives while utilizing cutting-edge tools and...

5 days ago

  •   Less than 5 years exp.  •   Business Services

$200K - $235K *

Lead and innovate in our modeling group, managing a team of engineers to develop next-gen technology while ensuring seamless integration with AI and existing systems; collaborate closely with stakehol...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$145K - $175K *

Lead the charge in developing innovative full-stack applications, collaborating with cross-functional teams to deliver robust solutions while ensuring security and quality throughout the software deve...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$187K - $253K *

Lead the development of innovative software solutions, driving impactful features and system improvements in a collaborative environment. Utilize advanced programming skills to tackle complex challeng...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$126K - $213K *

Engage with us to design, build, and maintain cutting-edge cloud infrastructure. You'll enhance our Kubernetes platform, drive GitOps practices, and empower developers through automation and infrastru...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Join our team to deliver innovative waste management solutions. Collaborate with clients to optimize operations through tailored technology integrations and enhance sustainability efforts while drivin...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$150K - $180K *

Innovate by owning the architectural foundation for enterprise compliance. Lead complex initiatives, design scalable solutions, and drive alignment across teams to enhance security programs for divers...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Take ownership of the design and development of complex electromechanical systems, leading projects and teams to deliver innovative moving camera products while ensuring performance, reliability, and...

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$95K - $115K *

Join us to lead innovative water resource projects, mentor junior engineers, and ensure compliance with design standards while optimizing processes for efficiency and effectiveness across diverse proj...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$92K - $174K *

Advance your career by collaborating with engineers and scientists to develop innovative signal processing algorithms and tools that enhance sonar systems for national defense. Engage in multidiscipli...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$92K - $174K *

Unlock potential by joining a dynamic team focused on signal processing and data modeling. Collaborate across disciplines to develop innovative algorithms and tools that enhance sonar systems for nati...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $105K *

Join a team that's dedicated to elevating client support standards. You'll troubleshoot complex issues, foster client relationships, and collaborate with developers to enhance product documentation an...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform warehouse operations by designing and enhancing WMS applications. Collaborate with cross-functional teams to deliver reliable solutions, optimize performance, and support critical business p...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Transform the internal IT landscape by managing employee support, systems administration, and infrastructure scalability. Drive automation and security initiatives while enhancing user experience in a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$104K - $166K *

Unlock the potential of automation by developing end-to-end solutions using Ansible, Python, and RESTful APIs. Collaborate with cross-functional teams to enhance operational efficiency and support a s...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $185K *

Transform the future of engineering design by leading diverse teams to deliver high-quality electrical engineering solutions. Drive project success through strategic oversight, mentoring, and adherenc...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$110K - $183K *

Innovate the future of healthcare technology by developing scalable applications that streamline specialty prescriptions. Collaborate with a skilled team to enhance user experience and drive efficienc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$133K - $209K *

Join a dynamic IT team as you safeguard cloud infrastructure, enhance security measures, and lead incident response efforts. Your expertise will drive continuous improvement and ensure robust protecti...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $105K *

Drive cloud infrastructure excellence by managing environments, automating deployments, and ensuring security. Collaborate on cloud migrations and capacity planning while producing essential documenta...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$80K - $128K *

Develop engaging web-based training content and tools, ensuring accessibility and compliance. Collaborate on UI enhancements and create metrics dashboards to track user adoption for a federal data int...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$134K - $179K *

Shape the future of energy management by leading complex EaaS projects, optimizing system performance, and mentoring technical teams in a collaborative environment focused on excellence and client sat...

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.