Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$80K - $95K *

Join a dynamic team as a Project Engineer, driving innovative medical device projects from concept to commercialization while collaborating with cross-functional teams and engaging with customers to e...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a team that's transforming healthcare automation by leading the design and delivery of intelligent solutions in Revenue Cycle Management, specializing in computer vision-driven RPA to enhance ope...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$118K - $180K *

Unlock potential by leading structural engineering reviews for renewable energy projects. Collaborate with multi-discipline teams to optimize design, support financing, and deliver actionable insights...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Technical Services

$140K - $200K *

Shape the future of mixed-signal IC design by leading EDA/CAD efforts. Collaborate with a skilled team to drive innovative solutions from concept to production, ensuring high-performance layouts and t...

Yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Shape the future of cloud security solutions by leading technical sales pursuits, collaborating with clients and internal teams to deliver tailored compliance strategies and drive successful implement...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$212K - $265K *

Advance your career by leading the design of scalable insurance systems, collaborating with cross-functional teams to enhance product offerings and drive technical excellence in a dynamic environment...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$110K - $130K *

Lead the charge in optimizing cloud environments as a DevOps Engineer. Collaborate across teams to enhance AWS infrastructure, automate processes, and ensure high availability and security for Java ap...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Transform your career by leading the technical direction for data visualization. Collaborate with a skilled team to design and build innovative visualization components, enhancing customer interaction...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform data services by developing and modernizing ETL processes, data integration, and warehousing solutions. Collaborate with cross-functional teams to enhance data quality and performance in a h...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$140K - $160K *

Drive the development of critical enterprise applications for defense personnel, utilizing Java, Spring Boot, and Angular. Collaborate in an agile team to enhance program and financial management tool...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$220K - $290K *

Accelerate the development of autonomous systems by leading systems engineering strategies, aligning cross-functional teams, and ensuring rigorous safety and performance standards throughout the produ...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$118K - $219K *

Transform your career by leading the integration and testing of advanced satellite systems. Collaborate with diverse teams to ensure robust solutions, driving technical planning and validation for nex...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$113K - $140K *

Champion the reliability and performance of critical systems, driving architecture evolution and incident response. Collaborate with a skilled team across AWS and Azure, ensuring security and scalabil...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $135K *

Shape the future of IoT solutions by leading backend cloud services development. Drive technical design, mentor engineers, and ensure scalable architecture for AWS-based applications while enhancing u...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$87K - $209K *

Join a dynamic team to design and implement backend services, enhancing developer tooling and integration frameworks. Drive improvements in performance and resilience while collaborating with cross-fu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$75K - $140K *

Drive innovation by developing and deploying AI algorithms for mission systems, overseeing the entire technology lifecycle from requirements to testing, and enhancing autonomy in products through adva...

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$75K - $140K *

Develop and integrate AI algorithms for mission systems, overseeing the full technology lifecycle from requirements to deployment. Collaborate across teams to enhance autonomy and machine learning cap...

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$75K - $140K *

Join a team that's developing cutting-edge AI and autonomy algorithms for mission systems. You'll support the entire technology lifecycle, from requirements generation to testing, ensuring innovative...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$62K - $141K *

Grow your career with a dynamic role focused on designing and implementing network solutions. Collaborate with diverse teams to deliver robust systems for voice, data, and security, ensuring seamless...

Today

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Unlock potential by designing and implementing enterprise identity solutions, ensuring secure access across cloud and hybrid environments while collaborating with cross-functional teams to enhance IAM...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Elevate your expertise by driving innovation in non-basic refractory products through R&D. Collaborate with global teams to optimize manufacturing processes, enhance product performance, and provide t...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Business Services

$168K - $181K *

Lead the charge in developing innovative AWS cloud solutions for scoring capabilities. Collaborate with cross-functional teams to enhance system reliability and efficiency, while mentoring junior engi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$87K - $293K *

Elevate your career as a data engineer, leading modernization efforts in data pipelines and governance for AI. Collaborate in agile teams to deliver trusted, productized data solutions that drive inno...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$87K - $293K *

Join a team that's transforming data engineering for AI. Lead modernization efforts with batch and streaming pipelines, ensuring data governance and quality for trusted AI consumption. Collaborate in...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$224K - $431K *

Innovate cutting-edge software for data center power management, spanning architecture, firmware, and AI workloads. Drive product lifecycle from design to deployment, enhancing performance and energy...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.