Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$73K - $220K *

Unlock the potential of mobile technology by leading a dynamic team to develop innovative applications. Collaborate with clients and offshore teams to enhance productivity and drive transactions in a...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Join a team that's dedicated to providing exceptional post-sales technical support for federal clients. You'll troubleshoot complex systems, collaborate with engineering teams, and ensure seamless ope...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$179K - $254K *

Join a team that's driving the future of mobility and IoT! Oversee product lifecycles, collaborate with executives, and navigate complex networks to align cutting-edge solutions with customer needs an...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Optimize AI infrastructure by designing APIs and resource management systems for GPU clusters. Collaborate with teams to enhance scheduling algorithms and ensure efficient resource allocation, impacti...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$108K - $162K *

Lead the charge in delivering exceptional technical support and project leadership for Digital CMU solutions. Collaborate with teams to ensure successful implementations, optimize system performance...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$145K - $160K *

Drive innovation by building scalable data integration solutions, collaborating with cross-functional teams to enhance healthcare technology. Ensure data quality and security while optimizing performa...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Transform processes by leading complex engineering projects, collaborating with cross-functional teams, and driving innovative solutions for efficiency and compliance in food and pharmaceutical manufa...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Elevate team performance by leading a Scrum team in developing and modernizing enterprise SaaS applications. Guide technical decisions, mentor engineers, and foster collaboration across departments to...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Join a team that's responsible for building and maintaining a scalable, secure, and performant Linux infrastructure through automation and modern tooling, ensuring high availability and adherence to b...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Transform the future of toolpath systems by developing algorithms that enhance milling machine efficiency and precision. Collaborate with a skilled team to tackle complex mathematical challenges and o...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Optimize marketing workflows by developing AI tools that enhance productivity across teams. Collaborate closely with stakeholders to build, maintain, and support innovative solutions that drive effici...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $160K *

Drive the development of critical enterprise applications for DoD personnel, enhancing program and financial management capabilities. Collaborate within a product team to modernize technology and deli...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $150K *

Transform your career by leveraging your AWS expertise in a dynamic DevOps role. Collaborate with a hands-on team to enhance infrastructure and streamline development processes while tackling complex...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$116K - $155K *

Join a dynamic team as you design and optimize Oracle EBS integrations, enhancing supply chain solutions. Utilize your expertise to drive impactful software engineering efforts that elevate business p...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$173K - $233K *

Unlock innovative solutions as you collaborate across teams to enhance user experiences on mobile and web platforms. Drive impactful projects, support product development, and contribute to a thriving...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$122K - $240K *

Transform the future of Human Capital by designing and delivering AI solutions that enhance data governance, model training, and real-time inference, collaborating with cross-functional teams to ensur...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$152K - $179K *

Join a team that's building innovative backend services for stablecoin issuance and operations. Collaborate with cross-functional teams to enhance adoption and drive growth through reliable, well-test...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Unlock innovation by designing backend services in Python and enhancing AI-powered search solutions. Collaborate in agile teams to create impactful enterprise search products while mentoring peers and...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $119K *

Lead the evaluation, design, and rehabilitation of bridge structures, ensuring compliance with design codes while collaborating with a dynamic team to deliver innovative solutions and enhance transpor...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Transform identity and access management by executing daily operations, supporting AI tooling, and managing SaaS vendor administration. This role offers hands-on experience and a clear growth path tow...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $185K *

Unlock potential by designing and maintaining scalable backend systems for complex data integrations. Collaborate with partners to enhance operational efficiency and reliability, ensuring seamless dat...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Engineer resilient backend solutions for privileged account discovery, enhancing security while navigating complex, customer-deployed environments. Collaborate on data-processing workflows using cutti...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$118K - $219K *

Unlock your potential as a Release Train Engineer, facilitating Agile processes and enhancing team collaboration to deliver exceptional value. Drive continuous improvement and support program alignmen...

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$95K - $115K *

Lead the development and optimization of manufacturing processes, ensuring technical integrity and continuous improvement. Collaborate with cross-functional teams to drive sustainable solutions and en...

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $115K *

Transform the future of software solutions by designing and delivering scalable applications for a critical onboarding platform, collaborating with cross-functional teams to enhance engineering qualit...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.