Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$92K - $110K *

Lead maintenance strategies to enhance automation systems' performance and reliability. Collaborate across engineering and operations to implement solutions, conduct analyses, and mentor junior staff...

1 month ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$78K - $98K *

Shape the future of AEC workflows by leading product ownership and Agile delivery for an Engineering Tools team. Collaborate with cross-functional stakeholders to prioritize needs, validate outcomes...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Elevate our search capabilities by architecting high-scale solutions, leading multi-quarter transformations, and ensuring operational excellence across a global cloud infrastructure while mentoring em...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$152K - $259K *

Transform security analysis by leading the development of a static analysis engine. Shape technical direction, mentor engineers, and drive initiatives that enhance code security and performance across...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$217K - $303K *

Lead the charge in evolving a cohesive design system for Android, enhancing UI architecture and performance. Collaborate with cross-functional teams to build reusable components and improve accessibil...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$225K - $265K *

Drive the development of seamless integrations for security platforms, leading a team to deliver high-quality, reliable products that enhance customer security stacks and ensure compatibility with evo...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Drive your career forward by enhancing developer tools and experiences. In this hands-on role, you'll modernize technologies, streamline workflows, and lead initiatives that boost productivity across...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $205K *

Join a dynamic team to lead AI agent deployments in healthcare. Leverage your software engineering expertise and client-facing skills to drive technical delivery, influence product development, and en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team to design innovative hardware solutions, ensuring project success through collaboration and technical expertise. Contribute to cost-effective designs while enhancing manufacturing...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Elevate your career by applying your hardware engineering expertise to design innovative solutions that meet customer needs. Collaborate across teams to enhance project execution and drive continuous...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Engineer innovative hardware solutions by collaborating across teams to deliver high-quality designs and optimize project execution, ensuring alignment with customer requirements and enhancing manufac...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$127K - $133K *

Engineer scalable cloud platforms by automating processes and enhancing reliability. Collaborate with teams to streamline deployments and ensure secure, resilient infrastructure that meets evolving bu...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$140K - $170K *

Advance your career by leading a dynamic team in developing secure access solutions. Drive technical direction, manage project delivery, and mentor engineers while balancing customer reliability with...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Empower our global technology infrastructure by managing and optimizing IT systems, cloud services, and cybersecurity initiatives. Collaborate with a talented team to drive digital transformation and...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Build and operate a governed data platform that transforms data architecture into reliable pipelines and analytical models, driving advanced analytics and decision-making across business teams and tec...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$120K - $145K *

Accelerate your career by designing and optimizing secure, scalable cloud infrastructure. Collaborate with cross-functional teams to enhance operational efficiency and ensure high availability for glo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$52K - $112K *

Join a dynamic team to manage IT projects in the banking sector, focusing on payments. Collaborate with stakeholders to define project scope, deliver documentation, and ensure successful product deliv...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Empower creativity by transforming ambitious concepts into innovative digital experiences. Collaborate with designers and engineers to prototype and build interactive projects, leveraging your technic...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$138K - $165K *

Shape the future of consumer applications by leading machine learning and Generative AI initiatives. Build robust data pipelines, develop and deploy models, and drive business impact through experimen...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$162K - $211K *

Join a dynamic engineering team to build and maintain production platforms, driving architectural decisions and mentoring junior engineers while ensuring system reliability and integration with IT Sec...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $190K *

Innovate scalable, cloud-native APIs with .NET and Java/Kotlin. Lead architecture discussions, enhance core offerings, and collaborate across teams to deliver high-value system components in a dynamic...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$120K - $145K *

Unlock potential by leading complex engineering initiatives across Microsoft 365 collaboration services, ensuring secure, reliable solutions while mentoring engineers and enhancing platform health thr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$215K - $315K *

Lead the charge in building secure, compliant infrastructure for our DaaS platform. Drive engineering excellence while collaborating with cross-functional teams to meet the needs of regulated customer...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$210K - $247K *

Elevate application security by leading initiatives and shaping best practices across multiple programming languages, while collaborating with engineering teams to ensure that security is integrated a...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in integrating and managing machine certificate authentication across Windows endpoints, ensuring secure device authentication and reliable certificate lifecycle processes in a dynamic...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.