Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$143K - $241K *

Collaborate with cross-functional teams to design and implement scalable data solutions, optimize performance, and enhance software architecture while adhering to coding standards and leveraging AI to...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$144K - $241K *

Lead the charge in architecting and enhancing AI systems that empower global journalism. Drive technical direction, ensure system scalability, and mentor engineers while shaping the future of content...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$150K - $180K *

Transform the foundational platform that powers diverse products by leading design and evolution efforts, driving product velocity, and ensuring reliability and scalability for a variety of deployment...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$209K - $273K *

Drive innovation by owning customer-facing products end to end, leading technical strategy, and shaping product direction. Collaborate across teams to build AI-native experiences that enhance user eng...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $140K *

Transform your career by leading complex design change projects from inception to execution. Collaborate with cross-functional teams, manage substantial budgets, and drive innovation in a fast-paced e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $200K *

Deliver innovative backend solutions that enhance integrations and streamline security workflows. Collaborate with experts to build reliable services, ensuring seamless connectivity and improved inves...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Transform the future of semiconductor assembly by designing and testing high-performance electro-mechanical systems. Collaborate with cross-functional teams to ensure reliability and manufacturability...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$131K - $243K *

Engineer cutting-edge avionics solutions by leading development lifecycles, conducting critical analyses, and collaborating with cross-functional teams to ensure compliance and performance excellence...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$220K - $240K *

Innovate customer-centric digital strategies, leading engineering teams to enhance e-commerce platforms and mobile applications, driving measurable growth in traffic, conversion, and satisfaction thro...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Staffing

$120K - $135K *

Join a team that's shaping the future of digital services for Veterans. As a Senior Software Engineer, you'll design and maintain scalable applications, collaborate with cross-functional teams, and me...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$153K - $213K *

Drive efficiency by automating internal processes, enhancing productivity across teams. Collaborate with stakeholders to identify bottlenecks, implement AI solutions, and ensure measurable impact on w...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$146K - $206K *

Join a team that's driving innovation in card acquisition by leveraging technology and data insights to create seamless user experiences and foster customer loyalty. Collaborate with cross-functional...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $200K *

Lead the architectural strategy for next-gen AI systems in immersive computing, focusing on hardware design for AI inference and imaging pipelines across VR, AR, and wearable devices, ensuring optimal...

RemoteRemote

5 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$83K - $222K *

Elevate healthcare technology by designing and implementing scalable web services and APIs. Collaborate with a dynamic team to deliver innovative solutions that enhance patient care and streamline ope...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Lead the modernization and sustainment of complex software systems, enhancing quality and performance while collaborating with cross-functional teams to reduce technical debt and ensure mission-critic...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$160K - $200K *

Drive technical excellence by designing systems, setting standards, and mentoring engineers without formal management. Collaborate with Product to ensure alignment and tackle engineering challenges ac...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $214K *

Lead the charge in designing and implementing enterprise Finance solutions, optimizing processes, and driving global transformation initiatives through innovative technology and collaboration with sta...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$135K - $165K *

Engage with our Cal AI team to enhance user experiences through innovative iOS development. Collaborate, mentor, and implement high-quality features that empower users on their health journeys while f...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Join a team that's shaping customer experiences through innovative frontend solutions. Take ownership of technical execution, collaborate across disciplines, and elevate engineering standards while en...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$164K - $262K *

Take ownership of software architecture and development to create scalable, user-centric applications. Lead comprehensive development initiatives while optimizing performance and mentoring engineers i...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$179K - $224K *

Join a team that's dedicated to delivering high-quality member-facing systems. As an Engineering Manager, you'll lead a squad through the entire development lifecycle, ensuring accountability, quality...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$232K - $341K *

Unlock potential by leading the technical strategy for enterprise architecture, focusing on AI integration and cloud migration. Collaborate with engineers to solve complex challenges and drive innovat...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Engineer innovative cloud infrastructure solutions, driving modernization and automation. Collaborate with cross-functional teams to enhance system reliability and scalability, supporting enterprise o...

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$500K+*

Join a team that's redefining AI/ML model serving infrastructure at scale. Lead innovative solutions for real-time and async workloads, optimizing GPU utilization while embedding AI capabilities into...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Hospitality & Recreation

$95K - $115K *

Join a team that's redefining network solutions by designing, implementing, and supporting advanced LAN, WAN, and wireless systems. Collaborate with cross-functional leaders to enhance network strateg...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.