Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$150K - $180K *

Develop and manage scalable AI infrastructure solutions, ensuring secure access to foundation models. Collaborate with cross-functional teams to enhance platform capabilities and drive AI adoption whi...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$118K - $219K *

Shape the future of engineering projects by leading program development, managing budgets, and collaborating with teams to enhance processes and customer relationships in a dynamic environment...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$95K - $178K *

Advance your career by leading project management efforts in missile defense. Collaborate with diverse teams to drive technology development, manage budgets, and ensure efficient execution of innovati...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $180K *

Lead and grow a high-performing platform engineering team, setting vision and roadmap while collaborating with cross-functional leaders to enhance product velocity and reliability for enterprise custo...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$155K - $165K *

Lead engineering teams to drive technical excellence in systems integration and testing. Manage projects, resources, and continuous improvement initiatives while aligning engineering activities with b...

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$145K - $269K *

Drive your career forward by leading the integration and delivery of advanced ground systems for a next-gen MILSATCOM program. Collaborate with cross-functional teams to ensure successful system perfo...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Elevate your career by leading a dynamic Engineering team, driving innovation in manufacturing processes, and collaborating across departments to enhance product development and operational efficiency...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Empower a dynamic team of software engineers to innovate and deliver impactful tech solutions, collaborating with cross-functional partners to enhance pediatric healthcare for children with special ne...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Transform mission-critical applications by designing and developing scalable solutions. Collaborate with cross-functional teams to ensure reliability and performance while leveraging cloud infrastruct...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$190K - $200K *

Lead the charge in electrical engineering excellence across multiple campuses, ensuring robust design, validation, and energization of critical infrastructure while integrating onsite generation solut...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Innovate and optimize software solutions that transform construction processes. Collaborate across teams to develop 3D visualization tools, leveraging AI and geospatial data to enhance project managem...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Partner with us to drive customer success by implementing and expanding Teleport solutions. Leverage your expertise to enhance adoption, troubleshoot issues, and deliver tailored training, ensuring cl...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Advance your career by building high-throughput services that power AI workflows. Collaborate with cross-functional teams to design scalable infrastructure and tackle complex challenges in a dynamic e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$125K - $150K *

Join our dynamic team as you lead Methods and Insights, driving engineering excellence through effective people management, operational delivery, and innovative system building. Empower engineers to t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Innovate with us to develop and support software solutions using AI-enabled tools, .NET, and SQL. Collaborate across teams to streamline ERP systems, engage in testing, and ensure project delivery acc...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$113K - $170K *

Lead the charge in transforming customer integrations by driving technical discovery, scoping complex implementations, and ensuring successful onboarding for high-stakes accounts. Collaborate closely...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $185K *

Unlock potential by driving innovative infrastructure solutions for scalable deployments, collaborating with customers to refine requirements, and enhancing operational efficiency through automation a...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$108K - $130K *

Elevate your career by leading engineering activities, managing resources, and ensuring high-quality technical deliverables while fostering collaboration across teams to achieve project goals within b...

Reposted 2 days ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Lead the charge in building high-performing software teams, focusing on coaching, development, and delivery. Collaborate with Product to ensure project success while maintaining a culture of engineeri...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$63K - $129K *

Contribute to system quality by executing test cases, analyzing requirements, and validating functionality to ensure compliance and stability in a fast-paced environment. Collaborate with teams to enh...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Join a team that's shaping the future of maritime data management and AI. You'll develop cutting-edge applications and enhance warfighter capabilities through innovative data solutions...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$229K - $260K *

Drive the technical direction for building and delivering containerized applications, ensuring reliability and security across deployments. Collaborate with teams to enhance automation and mentor engi...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Engineer innovative optimization models to enhance workforce planning and scheduling in a large-scale contact center. Collaborate with cross-functional teams to transform complex business needs into e...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Innovate your career by leading SaaS modernization projects, enhancing delivery efficiency through AI and automation. Drive customer success by transforming legacy systems into scalable, sustainable s...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $160K *

Transform healthcare technology by owning core products, driving architectural decisions, and ensuring high-quality code. Collaborate across teams to deliver impactful solutions that enhance patient c...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.