Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$130K - $170K *

Champion innovative solutions by designing and implementing core platform features, driving the transition to microservices, and collaborating across teams to enhance scalability and flexibility in Io...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$187K - $234K *

Empower the Integrations team to scale impact by leading third-party integrations, creating reusable capabilities, and fostering a collaborative culture that drives effective delivery and continuous i...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$159K - $254K *

Join a dynamic team to design and deliver innovative Android system applications, enhancing device management and user experience. Collaborate across functions to build scalable solutions that empower...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Take ownership of IT infrastructure and security operations, driving the migration to a Nutanix-based IaaS environment. Collaborate with teams to enhance security, compliance, and automation, utilizin...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$250K - $400K *

Shape the future of AI by partnering with customers to design and deliver innovative data solutions. Collaborate with a senior team to tackle complex challenges and transform vague requests into actio...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$127K - $170K *

Join us to lead complex technical initiatives, providing hands-on expertise while shaping architecture and design. Influence roadmaps, mentor engineers, and drive modernization across systems, ensurin...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$127K - $170K *

Engineer complex technical solutions while leading high-risk initiatives. Drive architectural decisions, mentor teams, and resolve critical production issues across multiple systems, ensuring alignmen...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Develop innovative software solutions for implantable medical devices, leading design and implementation while ensuring compliance with regulatory standards. Collaborate with cross-functional teams to...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$212K - $265K *

Elevate your career by developing cutting-edge cloud infrastructure that powers seamless operations across teams. Collaborate with talented engineers to enhance reliability, scalability, and efficienc...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$133K - $181K *

Champion innovative software solutions for optimal customer experiences. Lead development of full-stack web applications, enhancing shipping logistics. Collaborate with cross-functional teams to drive...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Transportation

$80K - $95K *

Unlock potential by driving process development and quality improvement initiatives. Collaborate with production teams to enhance product quality and resolve issues, ensuring customer specifications a...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$69K - $107K *

Champion client success by leveraging technical expertise to enhance platform value, optimize workflows, and drive measurable outcomes. Collaborate with cross-functional teams to deliver innovative so...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$162K - $258K *

Drive the design and implementation of cutting-edge GenAI solutions, leading the development of LLM capabilities and ML pipelines to enhance insurance workflows and deliver impactful outcomes for cust...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$157K - $184K *

Drive impactful backend services and APIs for customer-facing platforms, collaborating with cross-functional teams to enhance product features in a fast-paced, product-driven environment. Embrace qual...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$195K - $225K *

Innovate within a dynamic team to design, develop, and deploy advanced applications for a transformational initiative. Lead technical solutions and mentor engineers while ensuring optimal application...

United StatesRemote

Reposted 1 month ago

  •   11 - 15 years exp.  •   Information Technology

$157K - $184K *

Engineer and elevate our core product by developing innovative features, tools, and infrastructure while collaborating closely with a dedicated team to maintain high-quality standards and drive techni...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $190K *

Lead the charge in designing and optimizing scalable data pipelines using Azure, PySpark, and Airflow. Collaborate with teams to ensure data quality and performance while mentoring engineers and drivi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$140K - $160K *

Accelerate progress at our integration platforms, ensuring scalable, reliable data flows. You'll design, build, and optimize workflows while collaborating across teams to enhance performance and custo...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$113K - $191K *

Innovate by designing and operating scalable data infrastructure for petabytes of data, enabling customer-facing features and analytics across global industries, while enhancing systems for reliabilit...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$121K - $164K *

Champion a team of analysts to enhance enterprise infrastructure services, ensuring reliable support and operational excellence. Collaborate with cross-functional teams to align priorities and drive c...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $147K *

Elevate your career by contributing to critical systems engineering projects for the U.S. Air Force. Collaborate with a dynamic team to design, analyze, and document software systems, ensuring high-qu...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Join a dynamic team as you leverage your expertise in systems integration and testing to support critical defense programs. Collaborate on software engineering tasks, enhance operational capabilities...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Take ownership of systems engineering tasks, developing requirements and models while collaborating with stakeholders to deliver integrated solutions for strategic defense technologies. Support verifi...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Engage with a dynamic team to develop innovative systems solutions, ensuring technical excellence and strategic defense capabilities. Collaborate across disciplines to drive requirements and verificat...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$160K - $225K *

Lead the charge in enhancing inventory and supply chain systems through effective planning, optimization, and analytics. Drive technology choices while mentoring a team to ensure high-quality software...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.