Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$130K - $155K *

Join a dynamic team to architect and deliver a cloud-native maintenance planning tool, driving modernization efforts and collaborating with diverse stakeholders to ensure seamless project execution an...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Lead the development and operation of AI reasoning systems to enhance safety and efficiency in critical industries. Engage in multi-step LLM pipelines, ensure precision in product output, and work clo...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$255K - $290K *

Drive the technical vision for a complex database platform, ensuring scalability and performance. Lead architecture decisions, mentor engineers, and collaborate across teams to enhance data infrastruc...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$142K - $190K *

Unlock your potential by leading enterprise-level digital solutions, shaping engineering direction, and influencing cross-functional teams to deliver innovative customer experiences across web and mob...

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $92K *

Elevate your career by designing and developing enterprise applications that meet business needs. Collaborate with cross-functional teams to deliver scalable, secure, and high-quality software solutio...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $125K *

Pioneer the development of robust software solutions in eDiary and clinical data platforms, leveraging modern technologies to enhance patient engagement and ensure regulatory compliance while collabor...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Shape the future of technology as a senior technical leader, driving complex initiatives and mentoring engineers. Collaborate with cross-functional teams to deliver scalable, secure cloud-native solut...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Media

$133K - $213K *

Join a team that's shaping the future of online ordering by leveraging your full stack development skills. Collaborate across teams to design innovative solutions, enhance platform performance, and de...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$168K - $322K *

Build and operate core infrastructure services for global AI platforms, developing secure cloud-native solutions and orchestrating automation to enhance reliability and scalability in a collaborative...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Champion the development of scalable, cloud-native applications, enhancing data pipelines and integrations. Collaborate with teams to transform raw data into actionable insights, driving improvements...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$161K - $299K *

Drive system integration for satellite communications, leading technical development and analysis. Collaborate across teams to enhance designs, manage baselines, and ensure compliance while mitigating...

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $145K *

Transform the Web3 landscape by developing innovative dApps and backend services. Collaborate with cross-functional teams to ensure security, scalability, and seamless user experiences in a dynamic, r...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$85K - $120K *

Unlock innovation as a hands-on Software Engineer, driving Proofs-of-Concept and full software development cycles. Collaborate with senior engineers to explore emerging technologies while ensuring pro...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$85K - $120K *

Optimize the software development process by contributing to product-focused projects, addressing coding, debugging, automated testing, and performance enhancement to ensure scalable and efficient sof...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$223K - $317K *

Drive the evolution of a robust Fulfillment platform, shaping architecture and strategy while mentoring teams. Lead modernization efforts to enhance scalability, reliability, and performance, ensuring...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Join a team that's redefining internal tools for sourcing RFPs, leveraging modern technology and AI. Collaborate with diverse stakeholders while driving rapid experimentation and platform development...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$146K - $206K *

Unlock potential by leading software projects, collaborating with teams, and ensuring timely delivery while supporting product development and operational excellence in a dynamic environment...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Develop high-performance semiconductor assembly equipment by designing, testing, and documenting mechanical subsystems. Collaborate with cross-functional teams to enhance existing products and support...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the Mobile Development Productivity team, setting technical strategy and enhancing mobile app development efficiency. Collaborate with cross-functional teams to tackle challenges and drive innova...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$122K - $160K *

Transform the future of endpoint management by developing innovative solutions that enhance security and performance across diverse platforms, collaborating with a dynamic team to deliver impactful so...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Innovate with a dynamic team of engineers to shape architecture and drive product expansion as you build reliable software solutions for healthcare, fostering a collaborative environment that promotes...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$225K - $265K *

Accelerate progress at a mission-critical team, leading Data Streaming to enhance data ingestion pipelines. Build a skilled team, ensure pipeline reliability, and collaborate cross-functionally to sup...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Optimize your career as an Infor M3 Technical Consultant, leveraging 3-5 years of expertise in integrations and development. Collaborate with teams to design and support seamless enterprise solutions...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$181K - $226K *

Empower innovation as you develop and optimize networking software, collaborating with cross-functional teams to enhance product features and drive strategic decisions in a fully remote environment...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$144K - $209K *

Drive innovation by building scalable software solutions in a dynamic environment. Collaborate across teams to enhance user experiences and tackle complex challenges while leveraging cutting-edge tech...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.