Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$110K - $135K *

Collaborate with leaders to manage employee relations and complex investigations, providing expert guidance and risk assessments in a dynamic, regulated environment. Drive best practices and support w...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $120K *

Champion our legal team by providing expert guidance on employment and labor matters, ensuring compliance and risk management across diverse jurisdictions while collaborating with HR and business lead...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$150K - $190K *

Lead the charge in underwriting and managing complex enterprise accounts, driving profitable business through strategic broker partnerships while mentoring junior underwriters and shaping portfolio st...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Drive compliance excellence by enhancing oversight procedures and controls. Collaborate with stakeholders to streamline processes, conduct data quality assessments, and ensure adherence to regulatory...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $140K *

Transform your career by managing employee benefits for diverse clients. Collaborate with Producers and Executives to deliver exceptional service, analyze plans, and drive compliance while fostering s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Elevate your career by resolving complex commercial property losses, managing national accounts, and providing expert insights. Collaborate with diverse stakeholders while ensuring compliance and main...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Drive the future of AI & Analytics by leading client relationships, providing strategic guidance, and delivering innovative solutions. Leverage your expertise to enhance service delivery and ensure al...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $180K *

Transform your career by leading high-impact construction advisory services. Drive strategic client relationships, foster team collaboration, and innovate solutions to enhance project outcomes and pro...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$160K - $200K *

Unlock potential by leading high-performing teams in construction disputes and advisory. Drive client relationships, innovate solutions, and ensure quality execution while fostering growth and collabo...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$85K - $95K *

Transform client relationships by delivering exceptional service and support, ensuring seamless communication and issue resolution while collaborating with internal teams to enhance client satisfactio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$81K - $153K *

Champion financial examinations by leading teams to ensure quality, compliance, and timely delivery of regulatory services. Foster client relationships, manage complex projects, and drive growth in a...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $165K *

Join a dynamic team as a Managing Consultant, driving innovative solutions in Revenue Integrity. Oversee engagements, enhance client relationships, and lead project teams to optimize financial perform...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Join a team that's redefining litigation by engaging in high-stakes defense work. Collaborate with seasoned litigators to master trial preparation and strategy, while representing diverse clients in c...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $120K *

Engage with clients to optimize estate and tax planning, collaborating with internal teams to deliver exceptional service and measurable results. Lead projects from planning to implementation, ensurin...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Engineer transformative HR strategies as a trusted advisor, partnering with executives to tackle complex workforce challenges and align people initiatives with business goals in a fast-paced environme...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$95K - $115K *

Help us unlock potential by providing expert legal advice on complex contract claims, environmental law, and federal employment issues. Your role will involve research, analysis, and representation in...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$95K - $115K *

Transform legal strategies and support economic initiatives by advising on tax credits, drafting legislation, and ensuring compliance. Collaborate with diverse teams to enhance clarity in legal docume...

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $220K *

Shape the future of customer solutions by leading implementations and driving adoption of innovative technologies. Collaborate with teams to deliver tailored architectural designs that meet strategic...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive the enhancement of Compliance Monitoring and Testing programs, ensuring regulatory alignment and effective risk management. Collaborate with stakeholders to improve operational efficiency and su...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $132K *

Elevate the suitability review process for broker-dealer and investment adviser accounts. Analyze complex transactions, provide training, and drive process improvements while collaborating with Regist...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $185K *

Empower clients by leveraging deep ONESOURCE Direct Tax expertise to design innovative solutions using AI and automation tools. Engage directly with customers, manage projects, and drive efficiency wh...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$142K - $168K *

Transform client experiences by leveraging deep expertise in healthcare solutions. Lead strategic initiatives, enhance client relationships, and drive impactful outcomes for high-value accounts throug...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$175K - $200K *

Transform compliance within a dynamic enterprise by designing and overseeing an effective Ethics and Compliance Program that aligns with regulations and promotes enterprise growth. Drive culture and a...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Business Services

$174K - $224K *

Empower organizations by shaping data governance strategies that enhance security, compliance, and operational resilience. Collaborate with cross-functional teams to deliver impactful governance solut...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in driving client success by building trusted partnerships, understanding client objectives, and ensuring seamless delivery of services. Collaborate with internal teams to enhance sati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.