Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$95K - $115K *

Lead compliance excellence by conducting quality reviews, enhancing processes, and providing expert guidance to ensure timely, accurate client service and adherence to regulatory standards in a dynami...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Manage and litigate general liability claims, overseeing cases from inception to resolution while engaging with clients, drafting legal documents, and representing in various legal proceedings...

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$160K - $200K *

Champion the legal landscape for Phase 3 and commercial activities in the Americas, providing strategic counsel across the product lifecycle while partnering closely with commercial and medical affair...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a dynamic legal team to manage contracts, compliance, and governance. Collaborate with leadership to enhance legal processes and mitigate risks in a fast-paced environment, making a significant i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$180K - $220K *

Drive strategic client engagement and business development within assigned territories, fostering relationships with C-level executives in the legal sector to enhance growth and establish trust in tai...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$137K - $232K *

Manage complex workers' compensation cases, providing litigation services and strategic legal advice. Lead case handling from investigation to trial, ensuring optimal outcomes while mentoring support...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Join a team that's dedicated to enhancing attorney and paralegal development through strategic training, mentoring, and performance management initiatives, ensuring professional excellence and alignme...

4 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$71K - $106K *

Join a team that crafts compelling pitches and proposals for client-focused opportunities. Collaborate across business units in a dynamic environment, driving innovative solutions and business develop...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$88K - $105K *

Empower client success by managing relationships, analyzing trends, and providing strategic guidance. Lead initiatives in marketing, claims, and policy enhancements while mentoring junior staff to ens...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Unlock potential by managing environmental assessments across diverse projects. Collaborate with clients and lead fieldwork while ensuring quality control and effective communication throughout the pr...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $150K *

Drive your career forward by leading client engagement and market development in Knowledge & Research Services. Build relationships, shape client needs, and oversee impactful programs while collaborat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$101K - $131K *

Join us to lead life underwriting risk selection and strategy, ensuring financial strength and compliance while enhancing customer experience. Collaborate across functions to align decisions with mort...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $150K *

Shape the future of healthcare technology by leading clinical strategy initiatives to enhance drug diversion prevention and ensure patient privacy compliance. Drive impactful relationships, educate st...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Manage diverse tax projects, fostering client relationships and mentoring staff. Oversee tax return reviews and compliance, while identifying growth opportunities in a dynamic environment. Collaborate...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Shape the future of financial advisory by leading and developing a high-performing team. Drive growth, elevate client experiences, and build a culture of excellence, integrity, and ambition...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $210K *

Lead corporate legal strategy and M&A transactions, guiding complex deals and governance. Manage a growing legal team, develop processes, and partner with senior leadership to drive business initiativ...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Shape the future of consumer litigation by managing complex cases, providing strategic legal guidance, and collaborating with cross-functional teams to achieve effective resolutions while mitigating r...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in enhancing our business continuity and resilience program. Collaborate with teams to identify recovery priorities, assess risks, and implement actionable solutions that ensure operat...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $195K *

Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Join a dynamic team to support real estate litigation, managing cases and collaborating with seasoned attorneys. This role offers growth opportunities in a fast-paced environment, focusing on property...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $120K *

Manage a portfolio of strategic enterprise clients, fostering executive relationships and driving retention and adoption. Utilize data and AI tools to enhance client value, mentor team members, and sh...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $149K *

Join a team that's dedicated to providing legal support in mortgage servicing. You'll ensure compliance with regulations, draft essential documents, and collaborate with operational teams to minimize...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Join a dynamic national team to support complex asbestos litigation, collaborating with experienced attorneys on trial preparation, strategy, and client management across jurisdictions, while gaining...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $180K *

Champion strategic partnerships by providing expert legal guidance, managing complex negotiations, and enhancing scalable processes. Collaborate with cross-functional teams to drive business growth wh...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $140K *

Accelerate growth and expand market presence by developing strategic sales initiatives, managing national accounts, and building key industry relationships in the commercial real estate sector. Drive...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.