Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$72K - $146K *

Lead proactive business development initiatives, collaborating across teams to enhance marketing strategies and drive growth in Corporate and AI practices, ensuring measurable outcomes and effective c...

4 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$65K - $126K *

Drive impactful business development initiatives by collaborating across teams, translating priorities into actionable plans, and enhancing client relationships within a growing Corporate/AI practice...

4 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$72K - $146K *

Join a dynamic team as you drive impactful business development initiatives, collaborating across departments to enhance our Corporate and AI practices. Your role will be pivotal in translating strate...

4 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$168K - $210K *

Transform commercial agreements by drafting, negotiating, and closing enterprise SaaS contracts. Collaborate with cross-functional teams to ensure compliance and drive business growth while managing l...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Drive financial insights and reporting for North America, enhancing profitability and efficiency through data analysis and strategic forecasting. Collaborate with diverse teams to support informed dec...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$240K - $300K *

Drive revenue growth by engaging top-tier law firms, cultivating relationships, and executing strategic sales initiatives. Collaborate with leadership to exceed sales targets and enhance market presen...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $150K *

Develop and execute innovative strategies for employment law cases. Handle litigation tasks, mentor junior staff, and collaborate with a talented team to deliver exceptional legal services in a flexib...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Staffing

$125K - $150K *

Join a team that's transforming commercial transactions by providing expert legal counsel across diverse agreements. Collaborate with senior leaders to drive strategic initiatives while managing legal...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$178K - $225K *

Lead legal support for Finance and Capital Markets, ensuring compliance and strategic execution of ABS transactions and SEC reporting, while managing counsel and navigating complex agreements to drive...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$122K - $237K *

Join a team that's driving operational excellence in the Financial Services sector. You'll collaborate with leadership to implement strategic initiatives, enhance processes, and support financial and...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$122K - $237K *

Unlock potential by driving operational excellence and strategic initiatives within a dynamic team. Collaborate with leadership to enhance client service, implement process improvements, and manage fi...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$122K - $237K *

Drive operational excellence and strategic initiatives within a dynamic team, enhancing client service and efficiency. Collaborate with leadership to implement process improvements and leverage AI too...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$122K - $237K *

Manage operational excellence and strategic initiatives within a dynamic team, driving growth and efficiency in the Financial Services & Capital Markets sector. Collaborate with leadership to enhance...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$85K - $95K *

Transform complex medical malpractice claims by leveraging clinical expertise and analytical skills. Collaborate with teams to investigate, evaluate, and provide actionable insights, ensuring effectiv...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$141K - $234K *

Shape the future of privacy and AI governance by providing expert legal guidance on compliance with evolving regulations, collaborating cross-functionally to enhance governance programs, and ensuring...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive client satisfaction as a Senior Project Manager, overseeing eDiscovery projects, managing budgets, and consulting on best practices. Lead teams, enhance workflows, and ensure timely delivery whi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$95K - $115K *

Contribute to complex legal matters in the financial services sector, providing analytical support and collaborating with counsel. Engage with clients, regulators, and internal teams to ensure complia...

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Advance your career by leading complex architectural projects, ensuring design excellence and regulatory compliance while mentoring a talented team and collaborating across disciplines to deliver inno...

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Empower your career by serving as a legal partner in procurement and supply chain, providing expert guidance and support in contract negotiation, vendor relations, and operational risk management acro...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$170K - $195K *

Elevate revenue growth by building strong relationships with law firms and corporations. Drive new business development through consultative sales, leveraging industry insights and collaboration with...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$204K - $327K *

Drive innovative legal solutions as a key partner for AI and product teams, providing comprehensive guidance on regulatory challenges and product development. Collaborate cross-functionally to ensure...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Shape legal strategies at the intersection of healthcare technology and compliance. Provide expert guidance on contracts, cybersecurity, and regulatory issues while managing risks and ensuring adheren...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$141K - $234K *

Lead compliance initiatives in privacy, cybersecurity, and digital governance. Collaborate cross-functionally to enhance regulatory frameworks and provide strategic legal guidance to support business...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$92K *

Shape the future of special education by providing expert legal counsel to state-operated programs, ensuring compliance with laws and regulations while supporting policy development and litigation eff...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Collaborate with HR and legal teams to provide comprehensive employment law support, drafting and negotiating contracts while ensuring compliance with regulations. Balance legal risks with business ob...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.