Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Financial Planner (Kansas City, MO)
$106K - $125K *
Elevate client experiences by crafting tailored financial plans. Collaborate with advisors to deliver comprehensive strategies, ensuring accuracy and accountability while mentoring team members and en...
4 weeks ago
Field Supervision Director - Annuity
$108K - $130K *
Champion compliance and support for annuity transactions, guiding branch teams and Financial Advisors to ensure adherence to industry regulations while fostering a successful annuity business...
4 days ago
Senior Sustainability Consultant
$100K - $120K *
Elevate sustainability initiatives by leading client engagements in impact inventory, strategy development, and target tracking. Utilize analytical tools to transform sustainability challenges into ac...
Reposted 1 week ago
Transaction Advisory Services Manager
$117K - $158K *
Help us advance financial analysis by evaluating deal structures, managing projects, and delivering insights. Engage with clients, enhance value through collaboration, and lead junior team members to...
Reposted 2 weeks ago
$75K - $95K *
Unlock potential by managing accounting operations across diverse business units, ensuring accuracy and compliance in a fast-paced environment while driving improvements and supporting growth into a m...
2 weeks ago
Senior Application Security Engineer
$110K - $130K *
Join our Cyber Security team to spearhead a robust application security program, collaborating with developers to secure software and mitigate vulnerabilities. Help innovate security tools while enhan...
Reposted today
Associate Medical Director, Clinical Research
$225K - $281K *
Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...
Reposted 3 days ago
Senior Territory Manager, Independent Agency Channel
$100K - $120K *
Lead the charge in expanding business through independent agencies in your territory. Build relationships, drive adoption of quoting tools, and achieve production targets while providing valuable insi...
3 weeks ago
$170K - $200K *
Elevate the judicial landscape by serving as a United States Bankruptcy Judge, ensuring fair legal proceedings and upholding justice in the Western District of Missouri. This role demands integrity, l...
3 days ago
$193K - $244K *
Support business growth by drafting and negotiating partner agreements, providing strategic legal advice, and leading cross-functional projects. Collaborate with internal teams to ensure compliance an...
Reposted 4 days ago
Senior Graphic Designer, Legal Solutions
$88K - $105K *
Elevate brand identity by designing cohesive visual assets and systems. Collaborate cross-functionally to enhance marketing initiatives and ensure brand consistency across all platforms, driving recog...
Today
Senior Analyst, ALM & Treasury
$88K - $141K *
Empower financial strategies by analyzing interest rate and liquidity risks. Collaborate with stakeholders to enhance capital planning and reporting processes while ensuring compliance with regulation...
1 week ago
$80K - $95K *
Transform lender relationships by managing program performance, onboarding, and communication. Collaborate with leadership to identify trends and opportunities, ensuring clarity and efficiency in fina...
3 weeks ago
$90K - $110K *
Innovate data solutions by developing complex reports and analyses to support senior management and client needs. Collaborate with teams to enhance data literacy and provide technical guidance across...
1 week ago
Senior Product Enablement & Adoption Manager
$100K - $150K *
Empower members to fully engage with our product through strategic post-sale launches, driving adoption and enhancing user experience. Collaborate with cross-functional teams to ensure successful impl...
3 weeks ago
$100K - $120K *
Drive client success by enhancing revenue cycle performance and fostering strategic relationships with enterprise clients. Leverage expertise to implement solutions, manage risks, and ensure measurabl...
Reposted yesterday
$76K - $148K *
Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...
Reposted 1 week ago
$157K - $212K *
Lead the charge in enhancing AI search functionality, empowering legal professionals to seamlessly find documents. Collaborate with engineering teams to optimize search relevance, performance, and use...
Reposted 3 weeks ago
Senior Systems Specialist, FP&A
$116K - $157K *
Grow your career with our FP&A Systems team, designing innovative EPM solutions and enhancing financial planning processes. Collaborate with various stakeholders to optimize efficiency and ensure data...
Reposted 3 weeks ago
$80K - $95K *
Empower the clinical support team by coordinating complex cases, mentoring junior counselors, and enhancing protocols. Your expertise will drive effective communication and quality standards in geneti...
2 weeks ago
Senior Customer Success Manager
$115K - $125K *
Join a team that's dedicated to enhancing client relationships and driving customer success. In this role, you'll strategize and implement solutions, ensuring client satisfaction while collaborating w...
5 days ago
Senior Compliance Assurance Advisor
$110K - $130K *
Transform your career by leading compliance assurance initiatives that enhance the reliability of the North American electric grid. Collaborate with industry stakeholders to develop and implement risk...
2 weeks ago
$237K - $296K *
Join a team that's driving innovation in oncology by leading clinical development and medical affairs. Collaborate across functions to advance pivotal programs and ensure operational excellence in a f...
2 weeks ago
$110K - $130K *
Lead the charge in managing complex clinical trials, ensuring timely delivery, budget adherence, and high-quality outcomes while collaborating with multidisciplinary teams and stakeholders to enhance...
1 week ago
Senior Compliance Examiner/Auditor - MLR exams
$95K - $120K *
Unlock potential by conducting thorough MLR examinations, ensuring compliance with federal and state regulations. Collaborate with teams to analyze data, review documentation, and enhance audit proced...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.