Quality Systems Manager Jobs

Explore Quality Systems Manager opportunities with employers seeking experienced professionals to lead quality programs, strengthen compliance, and improve business processes. Ladders features vetted professional jobs paying $100,000 or more, including roles for quality leaders across regulated and highly technical industries.

What Does a Quality Systems Manager Do?

Quality Systems Managers develop and maintain the policies, procedures, and processes that help organizations consistently meet customer expectations and applicable standards. They may oversee quality management systems (QMS), coordinate audits, monitor corrective and preventive actions, manage documentation, and partner with teams across operations, engineering, manufacturing, and regulatory affairs.

Common Responsibilities

  • Lead the design, implementation, and ongoing improvement of quality management systems.
  • Prepare for internal, customer, and third-party audits and help resolve audit findings.
  • Track nonconformances, corrective and preventive actions, and quality performance metrics.
  • Maintain controlled procedures, records, and training programs.
  • Guide teams on quality standards, regulatory requirements, and risk management.
  • Identify process improvements that reduce defects and strengthen product or service reliability.

Qualifications and Skills

Employers commonly seek a bachelor's degree in engineering, science, business, or a related field, along with substantial experience in quality assurance or quality systems. Requirements vary by industry and role. Useful strengths include knowledge of quality standards and audit practices, analytical problem-solving, clear communication, project leadership, and the ability to influence cross-functional teams. Certifications such as Certified Quality Manager or auditor credentials may be valued for some positions.

Industries and Career Opportunities

Quality Systems Managers work in fields where consistent processes, customer confidence, and compliance matter, including medical devices, pharmaceuticals, aerospace, automotive, electronics, food production, and industrial manufacturing. Depending on the employer, the role may focus on a facility, product line, business unit, or enterprise-wide quality system, with opportunities to advance into director-level quality, compliance, or operational leadership.

Find Quality Systems Manager Jobs on Ladders

Search Ladders for vetted Quality Systems Manager jobs with salaries of $100,000 or more. Compare opportunities by industry, location, and seniority to find a role that aligns with your experience and career goals.

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$91K - $120K *

Drive quality assurance and compliance for GxP computerized systems, ensuring data integrity and regulatory adherence throughout the system lifecycle. Collaborate with cross-functional teams to enhanc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $120K *

Drive quality assurance and compliance for GxP computerized systems, ensuring data integrity and regulatory adherence throughout the system lifecycle. Collaborate with cross-functional teams to enhanc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$152K - $175K *

Shape and enhance the global Quality Management System for medical devices by driving compliance, governance, and continuous improvement while leading a dedicated team across multiple sites to meet re...

Massachusetts, USRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $172K *

Unlock potential by leading the design and deployment of a global Quality Management System, ensuring compliance and operational excellence across multiple aerospace sites while fostering collaboratio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $140K *

Pioneer GxP compliance in digital quality management, ensuring software and AI products meet regulatory standards. Collaborate with stakeholders to enhance quality processes and support audits, drivin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Drive quality assurance initiatives by overseeing computer system validation processes, ensuring compliance with GxP regulations, and collaborating with cross-functional teams to enhance validation pr...

Kentucky, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in ensuring quality assurance for transport and packaging validation, collaborating with cross-functional teams to uphold compliance and readiness for commercial launch while managing...

New York, USRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$126K - $145K *

Join a team that's dedicated to ensuring compliance and quality in GxP computer systems. Oversee validation and lifecycle management across clinical, quality, and manufacturing environments while coll...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive IT quality and compliance initiatives, managing audits and ensuring adherence to regulatory standards. Collaborate with global teams to enhance operational performance and support career develop...

Durham, NCRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $165K *

Bring your expertise to define and deliver enterprise integration products, optimizing data flow and connectivity across manufacturing environments. Collaborate with cross-functional teams to enhance...

Detroit, MIRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $400K *

Join a team that's shaping the future of digital supply chain management. You'll architect and optimize ERP, PLM, and inventory systems, ensuring data integrity and operational scalability across glob...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Transform workplace safety by leading initiatives, conducting assessments, and fostering a culture of compliance and performance. Collaborate with teams to implement effective health and safety strate...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $150K *

Lead complex project management initiatives across multiple channels in the pharmaceutical advertising sector. Oversee cross-functional teams, ensuring timely delivery within budget while mentoring ju...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead the design and implementation of GxP-compliant Quality applications, ensuring data integrity and regulatory compliance while mentoring junior team members and driving continuous improvement in a...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Oversee the design and development of clinical databases while ensuring project timelines and quality standards are met. Collaborate across teams to provide technical support and mentor team members...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join a dynamic team in managing project lifecycles by applying proven methodologies. You will lead diverse project teams, enhance client satisfaction, and promote continuous improvement while driving...

Philadelphia, PARemote

1 month ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$132K - $178K *

Lead a dynamic team to optimize quality oversight through data-driven insights, ensuring compliance and continuous improvement in R&D processes. Drive governance and operational excellence in quality...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Collaborate with sales and IT teams to transform operational data into actionable insights, ensuring effective system configuration and user adoption across Salesforce, CRM, and laboratory platforms t...

CanadaRemote

Today

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Transform sales operations by connecting teams and systems. Leverage data from Salesforce, LIMS, and CRM to create impactful reports and dashboards, driving performance improvements and supporting end...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$80K - $100K *

Manage and execute complex LIMS implementations for public health and environmental labs. Collaborate with cross-functional teams to ensure project success, stakeholder alignment, and high-quality out...

Tucson, AZRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $143K *

Join a dynamic team to lead Quality Assurance efforts in Long-Term Services and Supports. Oversee compliance, collaborate with external partners, and drive operational excellence while ensuring adhere...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Manage clinical trial operations, ensuring compliance and performance across protocols. Oversee submissions, budgets, and team coordination while collaborating with internal and external stakeholders...

Quebec, CARemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $173K *

Transform operational excellence by driving compliance and standardization across Plasma Procurement. Collaborate with leaders to enhance processes, implement Lean practices, and foster a culture of c...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Quality Systems Manager do?question toggle

    A Quality Systems Manager oversees the processes, documentation, audits, and improvement activities that help an organization meet quality standards, regulatory requirements, and customer expectations.

  • What qualifications are commonly required for Quality Systems Manager jobs?question toggle

    Many positions seek a bachelor's degree in a relevant field and significant experience in quality assurance, quality systems, or a regulated industry. Employers may also value audit expertise, standards knowledge, leadership skills, and relevant certifications.

  • Which industries hire Quality Systems Managers?question toggle

    Hiring industries include medical devices, pharmaceuticals, aerospace, automotive, electronics, food production, and manufacturing, as well as other sectors with complex quality or compliance requirements.

  • How much do Quality Systems Manager jobs on Ladders pay?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Actual compensation varies by employer, location, industry, responsibilities, and experience.

  • What skills are important for a Quality Systems Manager?question toggle

    Commonly valued skills include quality management system expertise, audit planning, corrective and preventive action management, regulatory knowledge, data analysis, process improvement, communication, and cross-functional leadership.