Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$150K - $170K *

Invent cutting-edge AI solutions for enterprise clients, driving efficiency and innovation. Collaborate closely with teams to transform workflows into actionable insights, delivering high-impact resul...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$68K - $103K *

Drive new business opportunities in biotech by leveraging integrated solutions to foster strategic partnerships. Collaborate with cross-functional teams to engage prospects and achieve growth targets...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Lead cloud architecture strategy and drive AI-enhanced solutions for scalable, secure platforms. Collaborate across teams to deliver innovative, resilient cloud solutions while mentoring engineers and...

US-AnywhereRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Accelerate progress at ensuring software quality by leading test automation for cloud services. Collaborate with cross-functional teams to enhance the reliability, usability, and stability of user-fac...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$254K - $361K *

Engage in leading and executing clinical trials for oncology products, collaborating with cross-functional teams to design protocols, analyze data, and report findings while ensuring compliance and sa...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Unlock potential by serving as a key technical resource in complex issue resolution. Collaborate with client-facing teams while driving critical investigations and ensuring product integrity through a...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$103K - $181K *

Manage comprehensive project control systems, fostering accurate financial tracking and collaboration across departments. Lead budgeting and analysis for various contract types, driving project perfor...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $150K *

Drive product success with your AI expertise, guiding teams to deliver impactful solutions. Own product strategy from roadmap to metrics, aligning cross-functional efforts to meet customer needs and b...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$140K - $180K *

Oversee Quality Assurance activities for manufacturing processes, ensuring compliance with FDA, EMA, and ICH regulations. Lead cross-functional teams to maintain product safety and quality standards w...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $180K *

Transform the quality assurance landscape by leading compliance and oversight for pharmaceutical manufacturing, ensuring regulatory adherence, fostering collaboration, and enhancing product integrity...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $110K *

Accelerate laboratory efficiency and innovation while supervising staff and managing operations, grant deliverables, and sample processing for groundbreaking research initiatives in blood cancers...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Collaborate with diverse teams to oversee clinical project management, ensuring operational excellence and compliance across multiple studies while driving corrective actions as needed...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Join a team that's pioneering explainable AI for compliance in wealth management. Lead engineering efforts, shape product direction, and drive innovation to transform manual compliance into efficient...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $150K *

Join a team that's building resilient infrastructure for a global medical AI platform. Apply your SRE expertise to enhance performance, reduce toil, and refine incident response, making a meaningful i...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $180K *

Collaborate with sales teams to solve complex client challenges and demonstrate Snowflake technology, thriving in a dynamic environment to deliver impactful solutions and support successful sales cycl...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $100K *

Optimize global Procurement strategies by analyzing supplier spend data, developing performance metrics, and streamlining technology tools to enhance operational efficiency and decision-making across...

US-AnywhereRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$90K - $130K *

Manage and oversee complex network fiber projects, ensuring successful execution through effective planning, project management, and team coordination while mentoring junior staff in a collaborative e...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$137K - $231K *

Join a dynamic team as you lead Solutions Architects, driving success in public sector sales. Oversee technical strategy and foster collaboration, ensuring customer mission alignment with GitLab's inn...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$206K - $275K *

Champion innovative developer experiences to empower engineers through effective CI/CD, tooling, and AI integration, driving productivity and measurable outcomes across the software lifecycle...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $120K *

Join a team that's passionate about data analytics! Leverage your programming expertise to ensure data integrity and drive impactful decisions in the pharmaceutical sector through collaboration and me...

US-AnywhereRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Elevate your career by leading supply chain operations and strategy, driving efficiency, implementing robust processes, and collaborating with teams to support clinical programs and commercial distrib...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Join the forefront of AI innovation by architecting and leading the development of cutting-edge GenAI platforms. Shape the future of agentic workflows and LLM-backed services while mentoring a team of...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $175K *

Drive strategic initiatives as Chief of Staff to the CEO, managing critical communications, executing special projects, and enhancing aiEDU's impact. Engage closely with leadership and external partne...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $130K *

Champion the development of procurement strategies to streamline operations across new warehouse facilities. Drive end-to-end sourcing, vendor management, and cost optimization initiatives, ensuring t...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Business Services

$130K - $180K *

Shape the future of drug discovery by driving scientific strategies and advancing candidates from computational models to real-world testing, while collaborating with multidisciplinary teams and manag...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.