Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$149K - $246K *

Lead the charge in revolutionizing clinical development through expert statistical oversight and collaboration on complex study designs and regulatory strategies, ensuring high-quality outcomes and in...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Engineer strategic transformation initiatives to modernize enterprise IT, overseeing program execution, Agile software delivery, and cloud adoption while ensuring compliance and alignment with DoD obj...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Elevate software delivery by managing the release lifecycle, coordinating cross-functional teams, and driving efficiencies through advanced tooling. Utilize program management expertise to ensure reli...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $120K *

Innovate in the bioscience sector by engaging customers, exploring opportunities, and securing contracts while collaborating with the marketing team to enhance market presence and awareness. Drive gro...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Explore business opportunities in biopharmaceutical science and technology. Engage with scientists, manage customer relations, and support marketing efforts to drive growth and brand awareness across...

US-AnywhereRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive strategic medical communication initiatives across therapeutic areas. Lead content development activities, manage project timelines, and oversee scientific staff to support client goals in the o...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join us in shaping the future of enterprise data architecture. Collaborate across teams to define standards, governance, and integration patterns, ensuring scalable, trusted data solutions support ana...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$224K - $356K *

Explore a pivotal role shaping AI platforms, blending technical leadership and engineering to deliver innovative marketing solutions that drive engagement and efficiency across AI ecosystems and enter...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$141K - $191K *

Empower healthcare innovation by leading strategic scientific communication initiatives in obesity treatment, ensuring impactful engagement with medical professionals through collaboration across func...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $265K *

Empower innovation by translating security and compliance into executable AI controls. Establish operational patterns and metrics to ensure AI systems are effective, safe, and aligned with industry st...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Explore your potential as you lead cutting-edge research on wildfire risk estimation, combining satellite data and fire science to implement models that shape preventive measures against catastrophic...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$85K - $110K *

Lead the charge in developing innovative AI solutions, managing small-scale projects, and collaborating with cross-functional teams to enhance agentic workflows and maintain high-quality documentation...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Partner with us to drive global CMC regulatory strategies for biologics and vaccines. Take ownership of submissions and lifecycle management. Collaborate closely across functions to ensure compliance...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$109K - $151K *

Pioneer strategies in Amazon marketplace for diverse beauty brands, driving growth and optimizing performance. Lead and develop teams while managing P&L, fostering collaboration, and enhancing brand v...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$160K - $200K *

Collaborate with cross-functional teams to drive strategic growth, manage major client relationships, and deliver tailored solutions that enhance customer satisfaction and profitability while overseei...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Drive impactful programs as a strategic leader in Veteran healthcare, focusing on suicide prevention initiatives through planning, execution, and stakeholder collaboration to enhance care for those at...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$118K - $177K *

Join a team that's dedicated to financial excellence by leading cost accounting operations. Collaborate across manufacturing to enhance profitability through strategic initiatives, financial analysis...

US-AnywhereRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Innovate in this executive role leading AI and data product strategies that enhance airline maintenance efficiency and reliability. Collaborate with technical teams to develop cutting-edge B2B SaaS so...

US-AnywhereRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$161K - $218K *

Lead the charge in developing innovative defenses against AI-driven security threats. Collaborate at the intersection of AI, cyber defense, and enterprise architecture to create scalable protections a...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$186K - $255K *

Join a team that's shaping the future of automation by managing large-scale projects and a talented team. Drive results with strategic leadership and ensure exceptional delivery across diverse custome...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$130K - $160K *

Lead the charge in securing AI systems and pipelines by assessing risks, building mitigation strategies, and developing automated security solutions to ensure safe, responsible deployment of AI-powere...

US-AnywhereRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Join a team that's creating impactful geospatial solutions by expertly managing and enhancing GIS capabilities. Engage in spatial analysis and automation to support critical initiatives while collabor...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$89K - $116K *

Lead the charge in driving cross-functional project initiatives, ensuring successful delivery from inception to completion while managing timelines, budgets, and stakeholder communications across mult...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$96K *

Unlock potential by joining our cutting-edge satellite remote sensing team. Collaborate with experts on innovative projects to enhance atmospheric data retrieval and analysis, while developing skills...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $150K *

Tackle the challenge of leading our Product organization. Guide a team in establishing a robust product operating system while maintaining high standards in product judgment and decision-making across...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.