Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$130K - $150K *

Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive the strategic direction of clinical studies in hematology-oncology, ensuring safety and efficacy of treatments. Collaborate across teams, author critical documents, and maintain compliance while...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Shape the future of quality management by leading global strategies, driving compliance, and fostering a high-performance culture. Collaborate with cross-functional teams to ensure top-tier quality st...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Engineer successful project setups and amendments for clinical trials, collaborating with internal teams and external partners to translate complex client requirements into actionable deliverables whi...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $155K *

Drive product development and commercialization initiatives while leading pilot deployments at customer sites. Engage cross-functional teams and ensure project execution aligns with strategic goals fo...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $115K *

Join a team that's dedicated to driving healthcare innovation through exceptional laboratory sales expertise. Collaborate with professionals to expand our Specialty Diagnostics portfolio and enhance c...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Shape the future of oncology by leading clinical development strategies and executing trials that support innovative therapies for cancer. Collaborate across functions to ensure alignment with company...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$167K - $278K *

Pioneer the AI platform architecture and strategy for scalable, production-ready solutions, enhancing innovation and operational excellence while fostering cross-functional integration and governance...

US-AnywhereRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$140K - $160K *

Join a team that's dedicated to environmental compliance and project management, overseeing assessments and remediation efforts for diverse clients. Balance office and field work while mentoring junio...

US-AnywhereRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Business Services

$165K - $207K *

Champion groundbreaking research in health economics and outcomes to drive evidence that enhances clinical strategies and informs commercial growth, collaborating with cross-functional teams to align...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead advancements in ionosphere and thermosphere modeling for space weather forecasts. Collaborate with scientists and forecasters to enhance predictive capabilities and improve operational applicatio...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$220K - $240K *

Join as a strategic leader in nonclinical safety for innovative therapies targeting CNS disorders. Your expertise will guide toxicology strategies from discovery through regulatory submissions, ensuri...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $160K *

Lead product strategy and lifecycle management for innovative cell culture solutions, driving portfolio growth and market success through collaboration with cross-functional teams and customer insight...

US-AnywhereRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $145K *

Drive growth in Arkansas by leading environmental projects, managing teams, and fostering client relationships. Oversee strategic business development and ensure regulatory compliance to make a meanin...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$109K - $147K *

Elevate bioanalytical methodologies by overseeing outsourced PK assay transfers and validations at CROs. Ensure compliance with regulatory standards while fostering collaboration and continuous improv...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join a team that's driving innovation in oncology by managing projects to advance approved imaging agents and late-stage products, enhancing lives through strategic planning, execution, and collaborat...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $113K *

Optimize distribution processes and enhance logistics operations through data-driven strategies and continuous improvements, driving efficiency and performance within a collaborative team environment...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $180K *

Accelerate progress at the intersection of engineering and research,leading a multidisciplinary team to transform ambitious scientific prototypes into reliable, scalable products while fostering colla...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$181K - $305K *

Lead the charge in advancing agent capabilities and AI systems, driving applied science strategy and influence across teams to deliver innovative, customer-focused experiences. Embrace cutting-edge re...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$83K - $125K *

Partner with us to enhance LC-MS applications in a field-based role, delivering training and scientific support while collaborating across teams to drive customer success and business growth across mu...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$466K - $500K+*

Drive cutting-edge research in probabilistic identity modeling for our new ad-tier. Engage in refining machine learning solutions while collaborating with cross-functional teams to advance user experi...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Unlock potential by partnering with leaders to enhance systems, culture, and the talent strategy needed for rapid growth, ensuring a high-performing organization thrives while navigating complex chall...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$425K - $500K *

Shape the future of scientific leadership as a strategic advisor, integrating innovation and technical expertise to drive organizational excellence, foster external partnerships, and support the devel...

US-AnywhereRemote

Reposted 3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Manage clinical trials to ensure compliance, timelines, and budgets while overseeing CROs and vendors. Be key in driving project success and maintaining data integrity and participant safety throughou...

US-AnywhereRemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Lead global clinical laboratory projects by ensuring operational excellence, client satisfaction, and effective cross-functional collaboration while mentoring junior project managers to elevate team p...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.