Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$90K - $120K *

Join a team that's redefining release management. Oversee the planning and execution of application and infrastructure releases while ensuring compliance, minimizing downtime, and driving process impr...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$189K - $246K *

Lead the charge in technical oversight of small molecule API development and manufacturing to drive successful product milestones and support lifecycle management. Collaborate cross-functionally to en...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$203K - $325K *

Lead the charge in transforming enterprise PMO initiatives by aligning strategic objectives with execution. Drive over 10 global programs, cultivating collaboration across functions to achieve operati...

US-AnywhereRemote

5 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$125K - $216K *

Lead the digital measurement and experimentation strategy across platforms, ensuring compliance and improving customer engagement through data-driven insights and A/B testing. Collaborate with cross-f...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $150K *

Engineer secure development practices and tools, ensuring software integrity throughout cloud and enterprise environments while leading security initiatives in an agile team setting...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$168K - $269K *

Manage the product vision and strategy for AI-enhanced equipment diagnostics. Drive user adoption and streamline workflows for technicians, ensuring valuable experiences with intelligent solutions acr...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$153K - $211K *

Manage the technical aspects of small molecule drug substance manufacturing and validation. Lead process improvements, handle cross-functional collaboration, and guide product transfers while ensuring...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Empower project success as a Program Manager, overseeing execution quality and financial performance across multiple commissioning projects while developing Project Managers to achieve strategic objec...

US-AnywhereRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Technical Services

$220K - $250K *

Engage as a key leader overseeing a major enterprise SaaS program, ensuring alignment across multi-workstream teams, and building strong relationships with strategic stakeholders for successful implem...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$138K - $190K *

Lead quality assurance efforts to enhance compliance and improve systems for clinical and commercial products. Collaborate across teams and partners to ensure adherence to global GMP regulations and s...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$138K - $190K *

Transform Quality Systems in GMP environments, ensuring compliance and driving continuous improvement while leading cross-functional teams and managing partnerships...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K *

Drive operational excellence and cross-functional alignment for global platform teams, ensuring measurable impact and continuous improvement. Lead a diverse team, fostering accountability while collab...

US-AnywhereRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$133K - $238K *

Empower the evolution of core technology platforms, uniting diverse teams to drive automation and robotics initiatives. Leverage your technical program management skills to deliver high-impact outcome...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$209K - $262K *

Drive architectural vision and strategies for scalable systems across diverse product squads ensuring top-tier technical excellence and compliance in healthcare solutions...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Deliver end-to-end bioprocess solutions by leveraging deep expertise in biopharmaceutical workflows, guiding complex customer collaborations, and driving high-impact project leadership for long-term s...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$136K - $184K *

Join a team that's shaping the future of oncology training. As a strategic leader, you'll enhance global scientific training initiatives and foster collaboration to empower medical teams with deep onc...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $181K *

Optimize sourcing strategies for new product introductions in Direct Air Capture. Collaborate with engineering and suppliers to scale critical components effectively while ensuring quality and reducin...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$91K - $121K *

Join a team that's redefining Waste-to-Energy solutions by providing senior technical leadership on combustion performance, driving operational improvements, and fostering cross-functional collaborati...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Energy & Utilities

$223K - $312K *

Serve as a key legal advisor, leading the negotiation and management of diverse contracts to support strategic growth in a dynamic biotech environment. Collaborate closely with teams to optimize proce...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$148K - $211K *

Lead integrated scientific and management efforts in imaging-driven clinical trials, providing expert guidance on analysis design, dosimetry techniques, and ensuring high-quality data delivery across...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Transform data analytics strategy by leveraging cloud technologies and AI/ML models. Drive innovation in data operations, ensuring secure access, governance, and scalable architecture to analyze and p...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $146K *

Design, build, and enhance AWS cloud infrastructures and CI/CD pipelines. Collaborate with cross-functional teams to ensure secure, reliable application delivery while optimizing operational workflows...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $180K *

Champion innovative AI solutions by leading design and deployment efforts to drive business value and ensure alignment with enterprise strategies. Collaborate with cross-functional teams to implement...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$189K - $315K *

Drive impactful scientific exchange and medical strategy execution, leveraging in-depth therapeutic knowledge to support healthcare professionals and optimize patient outcomes across diverse care sett...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Manage and optimize vendor relationships and supply chains to enhance healthcare outcomes. Collaborate cross-functionally to analyze demand, oversee inventory, and implement improvements, driving effi...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.