Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$210K - $245K *

Lead the charge in optimizing clinical outcomes and ROI methodology, shaping Foodsmart's data science strategy. Engage directly with payers and clinical teams, employing advanced research practices an...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$263K - $395K *

Shape the future of our mobile platform by leading architectural design and driving an innovative technical vision. Mentor teams, enhance performance, and build robust systems for scaling and reliabil...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$136K - $181K *

Unlock potential by leading a high-performing CRA team, ensuring compliance with ICH-GCP and local regulations while enhancing site relationships and driving clinical trial excellence. Spearhead resou...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $180K *

Join a dedicated team of experts shaping U.S. economic security policy. Leverage your analytical skills to navigate export controls, engage with interagency partners, and drive innovation in technolog...

US-AnywhereRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $150K *

Innovate cutting-edge bioinformatics solutions by applying data science expertise to complex genomic data. Collaborate with R&D teams to enhance diagnostic tests and streamline production pipelines wh...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the development of high-quality medical content and publications, driving strategic initiatives in oncology. Collaborate with cross-functional teams to ensure compliance, scientific integrity, an...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$208K - $260K *

Join a team that's transforming AI initiatives. Lead the architectural design and development of a centralized AI platform, driving technical vision and collaboration across teams to build scalable, s...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $110K *

Lead the development and implementation of robust account management programs, policies, and procedures across various areas. Collaborate with management to enhance operational effectiveness and drive...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$139K - $184K *

Drive regulatory excellence by managing submissions, guiding teams, and ensuring compliance. Utilize your expertise to support global projects and foster collaboration in a fast-paced environment focu...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead complex eDiscovery projects, managing client relations and team dynamics. Utilize expertise to drive project success, while mentoring junior staff and ensuring quality deliverables across multipl...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Oversee comprehensive data management activities for clinical trials, ensuring the development, implementation, and integrity of databases. Collaborate cross-functionally while maintaining compliance...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $169K *

Oversee complex capital projects in the manufacturing of PET containers, ensuring productivity, budget adherence, and safety standards. Collaborate with cross-functional teams to manage projects from...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$175K - $210K *

Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...

US-AnywhereRemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$108K - $127K *

Partner with us to enhance our sequencing analysis platform, driving stability and speed. You will tackle diverse challenges in pipeline engineering, operational tooling, and field support as part of...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Accelerate progress at a leading engineering team by designing and maintaining a large-scale, API-driven platform. Collaborate with senior engineers, mentor junior developers, and drive technical inno...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$118K - $219K *

Drive impactful healthcare solutions by leading product strategy and execution for innovative digital health initiatives, focusing on patient engagement and emerging technologies, while collaborating...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $190K *

Unlock potential by leading transformative Oracle Fusion Cloud ERP implementations. Collaborate globally with teams, manage critical processes, and drive innovation to enhance operational excellence a...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in evolving a robust SaaS platform while mentoring a high-performing engineering team. Balance hands-on coding with architectural leadership to drive innovation, scalability, and perfo...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$115K - $149K *

Lead the strategy and execution of upstream intelligence products, shaping customer decision-making using data and AI. Collaborate across teams to create impact-driven solutions that redefine agribusi...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $185K *

Unlock potential by leading an engineering team to enhance software solutions, integrating innovative AI practices while ensuring high-quality delivery across various client projects in a dynamic envi...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $220K *

Lead the charge in transforming AI technology into a secure, measurable capability for software engineering, collaborating across teams to innovate workflows and drive adoption through hands-on develo...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$201K - $251K *

Elevate employee experience through strategic global benefits management. Lead design and governance of diverse programs while partnering with cross-functional teams to ensure competitive and sustaina...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$164K - $226K *

Lead the charge in enhancing detection capabilities within our Rapid Response Team. Drive innovative solutions for emerging threats, fostering team growth while providing hands-on technical leadership...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$148K - $200K *

Shape your career by leading observational research projects that generate real-world evidence in oncology. Collaborate with multi-disciplinary teams to enhance data insights and drive strategic decis...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Discover an opportunity to lead clinical research initiatives, develop protocols, and drive program strategies, contributing to innovative therapies and collaborating across teams to ensure data integ...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.