Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$137K - $189K *

Shape strategic relationships with leading diagnostic organizations. Collaborate cross-functionally to enhance customer success, negotiate multi-million-dollar agreements, and drive long-term business...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the modernization of web applications by designing user-friendly interfaces, developing innovative features, and managing projects using contemporary technologies to enhance the delivery of criti...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $160K *

Unlock potential by serving as a strategic legal partner for enterprise sales, ensuring scalable contracts and compliance while driving revenue through expert negotiations and cross-functional collabo...

US-AnywhereRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$180K - $225K *

Lead the charge in transforming engineering practices across teams by improving architecture, design, and CI/CD. Contribute as a hands-on leader in building scalable production systems while mentoring...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Champion innovation by leading the development of AI-driven financial audit solutions, collaborating closely with engineering and clients to enhance efficiency and quality in audit processes across th...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$172K - $246K *

Lead the charge in shaping security governance by partnering with engineering teams, driving high-priority initiatives, and automating compliance processes to enhance operational efficiency and securi...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$214K - $264K *

Join a pivotal role in regulatory affairs, guiding promotional materials in compliance with FDA and provincial guidelines in a dynamic, remote environment. Lead the Materials Review Committee and shap...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Empower a dynamic team to lead analytical and programmatic support for key digital health initiatives within federal health agencies. Drive project success through data analysis, stakeholder engagemen...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$144K - $159K *

Drive the development of analytical methodologies for drug products, ensuring compliance and rapid advancement through key regulatory stages. Collaborate with internal teams and external partners to s...

US-AnywhereRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$136K - $178K *

Unlock advanced semiconductor testing by providing expert technical support for probe card products, collaborating across engineering, manufacturing, and customer teams to resolve complex issues and d...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$125K - $172K *

Elevate client success through innovative AI-driven healthcare solutions, leading collaboration with clients and teams to optimize product adoption and revenue cycle automations, fostering strong part...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $150K *

Lead the development of a cutting-edge data platform, driving innovation in cloud infrastructure and geospatial data systems to enhance scientific decision-making and support wildfire mitigation effor...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Innovate and impact the future of software solutions in an Agile environment. Collaborate with a dynamic team to enhance product development and deliver top-notch technologies. Bring your expertise in...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$303K - $410K *

Lead the charge in shaping frontier AI strategy, driving innovation through reinforced learning, multi-modal AI, and collaboration, while ensuring security, governance, and impactful outcomes across v...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$152K - $190K *

Pioneer transformative workflows by leveraging AI and automation tools to enhance efficiency across business domains, collaborating with leadership to implement impactful solutions and drive measurabl...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Drive innovation by leading the development of advanced analytics solutions, tackling complex business challenges, mentoring teams, and shaping strategic data-driven decision-making to significantly i...

US-AnywhereRemote

4 days ago

  •   11 - 15 years exp.  •   Information Technology

$85K - $110K *

Champion water resilience by managing complex projects focused on drinking water regulations, leading multidisciplinary teams and ensuring compliance with the Safe Drinking Water Act while delivering...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$180K - $210K *

Join us to shape compelling corporate narratives while partnering with leadership on strategic storytelling, product messaging, and go-to-market strategies for innovative AI-driven solutions within a...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Join a team that's pioneering reliability strategies for automated warehouse operations, ensuring peak performance and safety during startup and expansion. Drive enterprise-wide initiatives that enhan...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Deliver impactful engineering solutions by owning the Total Service Cloud ERP, leading cloud infrastructure management, and driving AI integration. Collaborate across teams to optimize performance, en...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Join a team that's redefining internal systems engineering. You will lead, inspire, and develop engineers while driving critical platform initiatives across identity, access, and ITSM, ensuring effect...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$298K - $368K *

Lead oversight of product safety, managing complex developmental programs and ensuring patient safety through comprehensive analysis and regulatory compliance. Collaborate with teams to address safety...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $132K *

Transform business efficiency by mapping workflows and deploying AI-driven automation solutions that drive significant productivity gains and align with leadership priorities in various operational do...

US-AnywhereRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$212K - $262K *

Deliver expert compensation strategies to support global business needs, advising on complex decisions related to equity, structure, and market competitiveness. Utilize extensive experience to enhance...

US-AnywhereRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$122K - $183K *

Lead the charge in shaping and executing the Regulatory Information Management strategy, ensuring data governance and compliance while fostering team development and cross-functional collaboration to...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.