Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Scientist, Process Chemistry
$165K - $185K *
Lead the charge in advancing drug substance processes, collaborating across teams to drive innovation and regulatory success. Leverage expertise to transform scientific ideas into viable commercial so...
Reposted 3 weeks ago
Principal Scientist Algorithm Lead
$151K - $175K *
Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...
Reposted today
Senior Scientist, Computational Materials Solutions
$100K - $125K *
Join a team that's revolutionizing materials innovation by applying computational science and machine learning. Collaborate with cross-functional experts to transform research breakthroughs into scala...
2 weeks ago
Principal Research Scientist - Frontier Industrial AI
$213K - $355K *
Tackle high-impact research in frontier industrial AI, developing innovative models, algorithms, and evaluation frameworks. Lead initiatives that push the boundaries of technology while collaborating...
3 weeks ago
$230K - $280K *
Shape the strategic vision and operational growth of project management practice, ensuring high-quality execution and client engagement while mentoring future leaders and driving continuous improvemen...
2 weeks ago
$192K - $288K *
Lead impactful R&D initiatives in proteomics, defining research strategy, managing complex projects, and mentoring teams. Collaborate cross-functionally to innovate and influence, ensuring scientific...
5 days ago
Senior Research Scientist, Evidence Synthesis
$100K - $140K *
Join a dynamic team as a Senior Research Scientist, where you will lead innovative projects in evidence synthesis. Collaborate with experts while managing deliverables and mentoring junior researchers...
3 weeks ago
Senior Manager, Development Quality
$125K - $150K *
Join us to elevate quality standards in radiopharmaceutical development. Lead GMP compliance and quality systems while mentoring junior staff. Drive improvement across our portfolio, ensuring regulato...
2 weeks ago
Senior Director/Vice President, Oligo Toxicology
$275K - $350K *
Join a team that builds integrated nonclinical safety strategies for oligonucleotide therapeutics, guiding studies from candidate selection through clinical development while ensuring scientific rigor...
1 week ago
Senior Director, AI Risk and Compliance
$167K - $278K *
Elevate your career by shaping AI governance and compliance frameworks that ensure responsible AI deployment while driving measurable business impact in clinical research. Lead a team committed to tra...
Reposted 3 weeks ago
Director, Product Development Quality
$150K - $180K *
Lead the charge in advancing quality assurance for cutting-edge radiopharmaceuticals. Oversee development quality, regulatory compliance, and team leadership, ensuring alignment with GMP and enhancing...
2 weeks ago
Senior/Staff AI Scientist, Target Discovery
$150K - $180K *
Engineer advanced protein design models and collaborate with experts to innovate in AI Drug Discovery, driving the development of candidate antibody therapeutics through deep learning and systems biol...
1 week ago
$80K - $95K *
Join a team that’s dedicated to enhancing national bathymetric models. Engage in data processing and validation, optimizing workflows, and contributing to improved marine navigation and hydrodynamic m...
4 days ago
Senior Technical Product Manager
$145K - $180K *
Champion innovative AI-driven solutions as you lead cross-functional teams to design, optimize, and deploy impactful biologic products. Play a vital role in bridging AI research and product developmen...
2 weeks ago
Sr Director, Product Development Lead - 591
$175K - $210K *
Pioneer advancements in oncology by leading global product development for late-stage radiopharmaceuticals. Collaborate across functions to meet objectives, manage risks, and ensure regulatory complia...
2 weeks ago
$120K - $190K *
Shape the future of AI alignment research by owning and accelerating innovative projects. Collaborate with engineers and scientists, publish findings, and engage with the AI community while developing...
2 weeks ago
$100K - $120K *
Elevate clinical research by assisting with study design, medical monitoring, and compliance to ensure effective execution of clinical trials and contribute positively to patient outcomes in alignment...
Reposted today
Senior Research Scientist, Evidence Synthesis
$100K - $140K *
Shape health technology assessments as a Senior Research Scientist. Collaborate on cutting-edge projects, mentor junior researchers, and manage client interactions to deliver impactful evidence synthe...
3 weeks ago
$165K - $290K *
Unlock potential by leading real-world evidence strategies for Cardiometabolic Health. Drive innovative data solutions, oversee impactful research initiatives, and collaborate cross-functionally to en...
3 days ago
$110K - $130K *
Manage and lead a team of Medical Scientists, ensuring compliance and support for clinical studies while driving medical innovation and operational excellence in life-saving projects...
1 week ago
$125K - $150K *
Help us shape strategic initiatives and connect expertise to deliver innovative solutions for clients. Collaborate across teams to enhance growth opportunities, strengthen relationships, and lead the...
3 days ago
Lead, Digital Product Manager- R&D
$125K - $157K *
Lead the transformation of R&D through digital innovation, managing product roadmaps, coordinating diverse teams, and ensuring user-centric software solutions deliver real business value and foster sc...
3 weeks ago
$141K - $196K *
Unlock potential by enhancing unsecured lending models through innovative machine learning research and implementation. Collaborate with cross-functional teams to translate research into scalable, rel...
3 weeks ago
$144K - $215K *
Drive cross-functional excellence by leading complex, enterprise-level programs, ensuring alignment with corporate goals while facilitating collaboration among diverse stakeholders for impactful outco...
3 weeks ago
Senior Director, AI Delivery & Operations
$167K - $278K *
Drive innovation by scaling AI engineering and platforms, ensuring operational excellence and robust delivery systems that enhance clinical research capabilities and streamline drug development proces...
Reposted 3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.