Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$79K - $157K *

Advance clinical data insights by reviewing and analyzing trial results, collaborating with cross-functional teams to ensure data integrity, and presenting findings to stakeholders, enhancing study ou...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $160K *

Drive client success in our lab network by managing relationships, ensuring renewals, and identifying growth opportunities. Collaborate across teams to enhance processes and improve client experiences...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$71K - $107K *

Join a team that's dedicated to providing high-quality nursing care in patients' homes. Collaborate with healthcare professionals to develop and implement care plans, ensuring continuity and excellenc...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $183K *

Lead the charge in delivering exceptional pharmaceutical care across multiple clinic locations. Collaborate with healthcare teams to optimize patient outcomes through effective medication management a...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$135K - $226K *

Lead a dynamic product team to enhance financial planning technology, empowering over 30,000 advisors to deliver exceptional client experiences through innovative solutions and strategic collaboration...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$96K - $141K *

Lead the charge in enhancing pediatric care by managing allied health services, ensuring evidence-based practices, and fostering clinical excellence for optimal patient outcomes and family engagement...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $289K *

Lead the charge in driving legal strategy and contract negotiations across all business units, ensuring compliance and supporting revenue growth through effective collaboration with sales, finance, an...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$79K - $118K *

Unlock potential by delivering exceptional nursing care in a dynamic environment. Collaborate with a multidisciplinary team to enhance patient outcomes, uphold safety standards, and engage in continuo...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...

United StatesRemote

3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Analyze clinical documentation and risk adjustment for healthcare providers, ensuring accurate representation of patient acuity. Collaborate with physicians to identify documentation opportunities and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $213K *

Join a team that's redefining clinical research by leading site activation strategies and ensuring efficient study start-up activities. Collaborate globally to drive operational excellence and mentor...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $213K *

Lead site activation strategies and study start-up activities, ensuring efficient initiation of clinical trials. Collaborate with cross-functional teams to manage timelines, mitigate risks, and enhanc...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$118K - $196K *

Lead the charge in developing and executing drug formulary strategies, ensuring compliance with regulations while collaborating with cross-functional teams to enhance pharmacy utilization management a...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in maximizing executive effectiveness and driving accountability within the Revenue organization as a trusted partner to the Chief Revenue Officer, while managing priorities, communica...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion financial excellence by leading a dynamic team, ensuring compliance, and delivering strategic insights to clients. Drive operational efficiency and foster a collaborative environment while ma...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $150K *

Drive strategic growth by building partnerships in the oncology sector. Engage with physician practices, support contract negotiations, and enhance service delivery through effective collaboration and...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$129K - $177K *

Transform Agile delivery by leading a complex Release Train, fostering collaboration, and driving continuous improvement across teams to achieve strategic business goals through the Scaled Agile Frame...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by owning customer value plans and ensuring adoption, ROI, and product usage for B2B SaaS accounts. Build trusted relationships with stakeholders, drive enablement sessions, and colla...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$67K - $101K *

Transform patient care by delivering high-quality nursing services in home settings. Collaborate with healthcare teams to develop and implement care plans, ensuring continuity and compliance with regu...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $175K *

Transform revenue operations by leading systems, data, and processes that unify Sales, Marketing, and Customer Success into a streamlined revenue engine, driving growth and efficiency across the organ...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $122K *

Shape the future of IT capabilities by leading requirements analysis and advisory support for a Department of War agency. Collaborate with stakeholders to deliver data-driven insights and enhance ente...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$274K - $371K *

Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$134K - $184K *

Shape the future of customer success by leading a high-performing team, optimizing operations, and driving engagement and retention strategies to achieve key performance indicators and enhance client...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $200K *

Unlock potential by driving sales strategies in the healthcare sector. Collaborate with C-Level executives, generate new opportunities, and enhance market presence while navigating complex enterprise...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Explore a unique opportunity to shape a new ambulatory surgery center, collaborating with a skilled team to deliver exceptional patient care and innovate surgical practices in a state-of-the-art facil...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.