Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Academic Neurohospitalist (MD/DO) - UNC School of Medicine
$210K - $250K *
Empower your career by joining a dynamic academic team focused on inpatient neurology. Engage in high-quality patient care, medical education, and scholarly activities within a nationally recognized m...
1 week ago
Senior Product Manager, Sales, Marketing & Business Solutions
$140K - $175K *
Join a dynamic team to drive the strategy and roadmap for Sales and Marketing platforms, focusing on Salesforce and marketing automation. Collaborate with stakeholders to prioritize initiatives and de...
1 week ago
Senior - Mergers & Acquisitions
$110K - $130K *
Unlock your potential by joining a dynamic team focused on delivering innovative financial solutions. Collaborate on due diligence projects, enhance client profitability, and leverage your accounting...
Yesterday
Senior - Mergers & Acquisitions
$100K - $120K *
Transform complex financial challenges into innovative solutions. Collaborate with clients to enhance their accounting and operational strategies, leveraging your expertise to drive impactful results...
Yesterday
Acoustics Engineer, Capacity Delivery
$100K - $120K *
Innovate noise control solutions for large-scale AI data centers. Lead acoustic studies, model sound propagation, and recommend effective mitigations while collaborating across engineering teams to en...
4 days ago
$174K - $239K *
Join a team that's transforming healthcare by providing strategic legal support for innovative oncology partnerships. Leverage your expertise to navigate complex commercial models while managing legal...
3 days ago
Family Medicine Residency Program Director (MD/DO) UNC Southeastern
$180K - $220K *
Join a team that's shaping the future of Family Medicine education through leadership and innovation in a dynamic residency program, focusing on resident development, clinical excellence, and communit...
1 week ago
Senior Solution Architect (US/Canada)
$120K - $145K *
Engage technical leaders by driving customer success through tailored onboarding, proactive relationship building, and facilitating effective implementation of solutions. Become a crucial bridge betwe...
1 month ago
Principal Scientist, Biologics
$150K - $180K *
Shape the future of oncology by leading biologics process development and manufacturing. Collaborate across teams to ensure compliance and quality in clinical-stage products, while mentoring scientist...
1 week ago
Regional Director of Operations - NC based
$100K - $120K *
Join a team that's dedicated to operational excellence and resident satisfaction. Lead multiple communities to achieve financial goals, enhance care services, and drive occupancy rates while fostering...
1 week ago
Regional Director of Operations - NC based
$100K - $120K *
Empower communities by leading operations to achieve resident satisfaction, occupancy, and revenue goals. Drive strategic initiatives, manage executive teams, and ensure compliance while fostering a c...
1 week ago
Senior Strategist, Paid Search B2B
$82K - $106K *
Advance your career by leading B2B paid search strategies and driving client growth through data-driven insights, performance management, and effective cross-team collaboration in a dynamic marketing...
Reposted 2 days ago
$70K - $115K *
Empower your career by joining a dynamic team focused on healthcare compliance auditing. Utilize your analytical skills to drive impactful audits and contribute to client deliverables while receiving...
5 days ago
Senior Software Engineer, Solutions Engineering
$179K - $224K *
Unlock innovative solutions as you guide software engineering teams to navigate complexities and enhance integrations while mentoring diverse talents in a collaborative environment...
Reposted 3 weeks ago
$140K - $185K *
Collaborate with cross-functional teams to drive product strategy, manage roadmaps, and enhance customer experiences. Lead product initiatives, ensuring alignment with business goals while mentoring j...
1 week ago
$80K - $95K *
Transform environmental projects by managing scope, budget, and client relations. Lead multi-disciplinary teams to ensure technical delivery and satisfaction while identifying growth opportunities in...
2 weeks ago
$163K - $245K *
Shape security architecture by designing robust frameworks across various tech domains. Collaborate with cross-functional teams to ensure comprehensive cybersecurity solutions aligned with business go...
Reposted 2 weeks ago
Director of Data Science and Bioinformatics
$186K - $232K *
Innovate within a dynamic team by establishing bioinformatics capabilities, architecting scalable infrastructure, and enhancing genomic algorithms to drive excellence in women's and organ health produ...
Reposted 2 weeks ago
Executive Director, Global Learning
$173K - $312K *
Empower organizational growth by leading global learning strategies, aligning workforce capabilities with business goals, and driving innovative solutions. Collaborate with senior leaders to enhance l...
Reposted 4 days ago
Executive Director, Global Learning
$173K - $312K *
Elevate global learning initiatives by leading strategy, governance, and innovation. Collaborate with senior leaders to identify capability gaps and drive impactful learning solutions that align with...
2 weeks ago
$136K - $214K *
Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...
2 days ago
$160K - $170K *
Join a team that's redefining production excellence by leading end-to-end photo and video shoots. You'll manage budgets, build partnerships, and create efficient workflows while ensuring brand integri...
1 week ago
Online Clinical Support Specialist
$92K - $138K *
Unlock your potential by joining a dynamic team focused on delivering top-notch Ultrasound IT support. Collaborate with customers to resolve complex technical issues in a fast-paced environment, ensur...
Reposted 1 week ago
$120K - $140K *
Drive product innovation in healthcare revenue cycle management by optimizing eligibility verification and enhancing payer connections. Collaborate with clients and internal teams to ensure effective...
Reposted 1 month ago
Software Engineer 4 - AI Native
$88K - $180K *
Accelerate progress at the forefront of AI-native software development. Drive engineering excellence by orchestrating autonomous agents and maintaining high-quality standards in a FedRAMP-authorized e...
4 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.