Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$210K - $250K *

Empower your career by joining a dynamic academic team focused on inpatient neurology. Engage in high-quality patient care, medical education, and scholarly activities within a nationally recognized m...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $175K *

Join a dynamic team to drive the strategy and roadmap for Sales and Marketing platforms, focusing on Salesforce and marketing automation. Collaborate with stakeholders to prioritize initiatives and de...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock your potential by joining a dynamic team focused on delivering innovative financial solutions. Collaborate on due diligence projects, enhance client profitability, and leverage your accounting...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Transform complex financial challenges into innovative solutions. Collaborate with clients to enhance their accounting and operational strategies, leveraging your expertise to drive impactful results...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Innovate noise control solutions for large-scale AI data centers. Lead acoustic studies, model sound propagation, and recommend effective mitigations while collaborating across engineering teams to en...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$174K - $239K *

Join a team that's transforming healthcare by providing strategic legal support for innovative oncology partnerships. Leverage your expertise to navigate complex commercial models while managing legal...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Join a team that's shaping the future of Family Medicine education through leadership and innovation in a dynamic residency program, focusing on resident development, clinical excellence, and communit...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Engage technical leaders by driving customer success through tailored onboarding, proactive relationship building, and facilitating effective implementation of solutions. Become a crucial bridge betwe...

RemoteRemote

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Shape the future of oncology by leading biologics process development and manufacturing. Collaborate across teams to ensure compliance and quality in clinical-stage products, while mentoring scientist...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's dedicated to operational excellence and resident satisfaction. Lead multiple communities to achieve financial goals, enhance care services, and drive occupancy rates while fostering...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Empower communities by leading operations to achieve resident satisfaction, occupancy, and revenue goals. Drive strategic initiatives, manage executive teams, and ensure compliance while fostering a c...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$82K - $106K *

Advance your career by leading B2B paid search strategies and driving client growth through data-driven insights, performance management, and effective cross-team collaboration in a dynamic marketing...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$70K - $115K *

Empower your career by joining a dynamic team focused on healthcare compliance auditing. Utilize your analytical skills to drive impactful audits and contribute to client deliverables while receiving...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$179K - $224K *

Unlock innovative solutions as you guide software engineering teams to navigate complexities and enhance integrations while mentoring diverse talents in a collaborative environment...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $185K *

Collaborate with cross-functional teams to drive product strategy, manage roadmaps, and enhance customer experiences. Lead product initiatives, ensuring alignment with business goals while mentoring j...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Transform environmental projects by managing scope, budget, and client relations. Lead multi-disciplinary teams to ensure technical delivery and satisfaction while identifying growth opportunities in...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$163K - $245K *

Shape security architecture by designing robust frameworks across various tech domains. Collaborate with cross-functional teams to ensure comprehensive cybersecurity solutions aligned with business go...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$186K - $232K *

Innovate within a dynamic team by establishing bioinformatics capabilities, architecting scalable infrastructure, and enhancing genomic algorithms to drive excellence in women's and organ health produ...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $312K *

Empower organizational growth by leading global learning strategies, aligning workforce capabilities with business goals, and driving innovative solutions. Collaborate with senior leaders to enhance l...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$173K - $312K *

Elevate global learning initiatives by leading strategy, governance, and innovation. Collaborate with senior leaders to identify capability gaps and drive impactful learning solutions that align with...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$136K - $214K *

Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $170K *

Join a team that's redefining production excellence by leading end-to-end photo and video shoots. You'll manage budgets, build partnerships, and create efficient workflows while ensuring brand integri...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$92K - $138K *

Unlock your potential by joining a dynamic team focused on delivering top-notch Ultrasound IT support. Collaborate with customers to resolve complex technical issues in a fast-paced environment, ensur...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$120K - $140K *

Drive product innovation in healthcare revenue cycle management by optimizing eligibility verification and enhancing payer connections. Collaborate with clients and internal teams to ensure effective...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $180K *

Accelerate progress at the forefront of AI-native software development. Drive engineering excellence by orchestrating autonomous agents and maintaining high-quality standards in a FedRAMP-authorized e...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.