Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$135K - $186K *

Lead strategic initiatives in the Endocrine space, maximizing sales and building relationships with healthcare providers. Drive education and support for rare CAH disease management while ensuring eth...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of healthcare revenue management by leading IDR processes, ensuring compliance, and driving data-informed improvements while mentoring a team of analysts to optimize workflows and enh...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Elevate our Enterprise business by building impactful relationships with brokers and consultants. Drive engagement strategies, generate new business opportunities, and enhance BetterHelp's presence in...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$155K - $410K *

Drive impactful payer modernization initiatives as a Director, leveraging data science to enhance operations and member experiences. Shape client relationships and guide teams in delivering innovative...

2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$155K - $410K *

Unlock potential by leading data science initiatives that enhance payer operations, drive business growth, and improve member experiences. Shape executive relationships and guide teams in leveraging d...

2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$100K - $120K *

Lead the charge in providing exceptional optometric care within a supportive, modern practice. Join a dedicated team focused on comprehensive and medical optometry, serving an established patient base...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a dynamic Wealth Management Team to drive client growth and retention. Lead business development efforts, manage a pipeline of leads, and ensure exceptional client experiences through proactive e...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $100K *

Help us unlock potential by delivering play-based ABA therapy and training staff. Collaborate with clinical peers to implement individual treatment plans and achieve excellent outcomes in a supportive...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance the adoption of cutting-edge prostate cancer imaging solutions while leading site activations, enhancing workflows, and ensuring optimal product utilization in the oncology sector, supporting...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive the standardization and oversight of product transfer processes, ensuring compliance with quality regulations while collaborating with internal teams to enhance product delivery and reliability...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $190K *

Champion growth by developing and executing strategic sales plans for tech-enabled services in the state and local government sector, driving client engagement and exceeding sales quotas through relat...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$153K - $255K *

Innovate security architectures by collaborating with cross-functional teams to design, implement, and monitor robust security solutions across cloud and on-prem environments, ensuring protection agai...

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$98K - $115K *

Empower individuals by providing tailored support in a collaborative environment. Join a passionate team dedicated to enhancing the lives of children with autism through innovative care and profession...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $275K *

Unlock potential by defining and driving the technical vision and product strategy for Next-Gen SIEM and Log Management products, ensuring alignment with market needs and customer motivations while fo...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $234K *

Lead and innovate technology solutions, enhancing operational efficiency while driving modernization initiatives to support diverse business goals in a collaborative and strategic environment...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $220K *

Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$91K - $152K *

Lead the charge in enhancing operational readiness for advisor and investor initiatives. Collaborate across teams to develop clear communication strategies and actionable plans that improve service de...

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$74K - $107K *

Join a team that's dedicated to enhancing patient care through comprehensive management and advocacy. This role involves collaborating with healthcare providers to ensure seamless transitions and opti...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Lead a multidisciplinary behavioral health team, balancing clinical and administrative duties. Provide expert guidance to clinicians while ensuring high standards of care and collaboration with interd...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by crafting stunning characters for gameplay and marketing. Collaborate with teams to push visual boundaries while adhering to production schedules and design constraints, ensuring to...

2 days ago

  •   Less than 5 years exp.  •   Media

$127K - $212K *

Champion secure architecture by conducting reviews and assessments for cloud and on-premise systems. Leverage your cybersecurity expertise to design solutions that align with security best practices a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$95K - $115K *

Empower patients by delivering compassionate care in interventional pain management. Collaborate with a multidisciplinary team to develop treatment plans and ensure optimal recovery, while managing op...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in delivering exceptional service and support to customers, managing maintenance operations, and executing technical strategies while fostering talent development and ensuring high-qua...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$108K - $162K *

Join a team that's dedicated to enhancing biomedical service operations. Lead a skilled team of technicians, ensuring high-quality support and customer satisfaction across the Pacific Northwest while...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$125K - $150K *

Shape data-driven solutions by leveraging your expertise in machine learning and analytics. Collaborate with cross-functional teams to deliver impactful insights and ensure seamless deployment in prod...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.