Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
NP or PA, MyCare 365 Primary Care & Urgent Care - Zebulon
$90K - $110K *
Partner with us to deliver exceptional patient care as a Physician Assistant or Nurse Practitioner, collaborating with a multidisciplinary team to provide both inpatient and outpatient services while...
1 week ago
Associate Director, Biostatistics
$174K - $203K *
Empower clinical innovations by leading statistical strategies in oncology trials. Collaborate with cross-functional teams to design studies, analyze data, and support regulatory submissions, ensuring...
Reposted 1 week ago
Sr. Software Engineer - Provider (Remote)
$110K - $130K *
Champion the future of mental healthcare by architecting innovative solutions for Provider Onboarding. Lead a dynamic team to enhance tools and workflows, ensuring seamless integration for users while...
2 weeks ago
$149K - $248K *
Drive your career with technical leadership in Palantir Foundry. Lead design, deployment, and enhancement projects for federal health initiatives, ensuring secure and scalable data architecture and op...
3 weeks ago
$117K - $148K *
Develop and implement innovative cloud solutions, collaborating with teams to enhance technology architecture and operational plans. Leverage expertise in cloud services to drive scalable, efficient s...
2 weeks ago
$74K - $93K *
Help us design and implement innovative information systems that meet user needs while aligning with our architecture. Collaborate on cloud solutions and AI-driven projects in a supportive environment...
2 weeks ago
$110K - $130K *
Manage and lead field-based medical teams, ensuring client delivery and team performance while fostering scientific engagement and program growth. Collaborate with cross-functional teams to achieve st...
3 weeks ago
$92K - $115K *
Transform client data integration processes by designing, building, and testing seamless connections between systems. Collaborate with teams to ensure optimal performance and security while delivering...
4 days ago
$80K - $115K *
Drive impactful storytelling and enhance brand reputation through strategic PR initiatives, collaboration with marketing teams, and management of agency partnerships. Elevate your communications skill...
2 weeks ago
Senior Legal Contract Manager (US)
$78K - $156K *
Join a dynamic team as you manage complex commercial contracts, balancing legal and business needs. Collaborate with cross-functional stakeholders to drive negotiations and enhance contracting process...
Reposted 3 days ago
Solution Architect, Legal Billing
$130K - $145K *
Help us design and implement billing solutions for law firms, leveraging your accounting expertise and software skills to streamline time entry, invoicing, and collections processes on the Litify plat...
Yesterday
Principal Technical Consultant, Paleontologist
$108K - $144K *
Shape the future of paleontological consulting by leading projects, mentoring teams, and driving business development while ensuring compliance and technical excellence across North America...
2 weeks ago
$95K - $115K *
Drive success as a Program Manager, leading a multidisciplinary team in delivering enterprise IT solutions, ensuring quality oversight, technical direction, and effective customer coordination across...
1 week ago
Senior Business Development - Public Safety
$120K - $135K *
Champion the growth of partnerships in the public safety sector, harnessing your sales expertise to cultivate high-level relationships, create member benefits, and drive innovative solutions that enha...
Reposted 2 weeks ago
$148K - $190K *
Join us to lead user experience design on our innovative learning platform. You'll own the design end-to-end, establishing a design system, shaping navigation, and enhancing the student experience thr...
3 weeks ago
Registered Nurse (RN) - PreSurgery Holding FT
$79K - $118K *
Drive exceptional patient care by assessing and preparing individuals for surgery, ensuring safety and comfort through clinical expertise and teamwork in a dynamic healthcare environment...
3 days ago
$83K *
Join a team that's dedicated to enhancing resident care by providing exceptional nursing services. This role involves supervising staff and ensuring compliance with health regulations while fostering...
1 week ago
$110K - $130K *
Manage comprehensive clinical data activities, ensuring oversight from study startup through database lock. Lead cross-functional teams, guarantee vendor performance, and uphold data quality standards...
1 month ago
Solution Architect, Identity Security
$200K - $250K *
Shape the future of enterprise solutions by bridging technical expertise and strategic vision. Collaborate with cross-functional teams to design impactful architectures that drive customer success and...
1 week ago
Program Administration Director
$130K - $216K *
Transform program administration for a large federal services initiative, overseeing workforce planning, financial operations, and compliance. Collaborate with diverse teams to enhance operational eff...
1 week ago
$120K - $145K *
Shape the future of client implementations by architecting efficient, scalable solutions. Collaborate with cross-functional teams to drive best practices and deliver strategic outcomes for leading pro...
5 days ago
Rare Disease Account Specialist - Portland, OR
$135K - $186K *
Lead strategic initiatives in the Endocrine space, maximizing sales and building relationships with healthcare providers. Drive education and support for rare CAH disease management while ensuring eth...
3 days ago
Lead Analyst, Independent Dispute Resolution (IDR)
$80K - $95K *
Shape the future of healthcare revenue management by leading IDR processes, ensuring compliance, and driving data-informed improvements while mentoring a team of analysts to optimize workflows and enh...
Yesterday
Consultant Relations Senior Manager
$170K - $200K *
Elevate our Enterprise business by building impactful relationships with brokers and consultants. Drive engagement strategies, generate new business opportunities, and enhance BetterHelp's presence in...
1 week ago
Payer Healthcare Data Scientist, Director
$155K - $410K *
Drive impactful payer modernization initiatives as a Director, leveraging data science to enhance operations and member experiences. Shape client relationships and guide teams in delivering innovative...
2 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.