Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$148K - $263K *

Drive the design and implementation of AI-First operational environments, architecting resilient multi-cloud networks and building autonomous orchestration layers to enhance security and efficiency ac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Unlock your potential by driving sales of innovative pulmonary solutions. Collaborate with diverse stakeholders to enhance patient care and achieve sales targets in a dynamic healthcare environment. J...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $138K *

Elevate your career by delivering expert clinical education and training. Drive customer success through hands-on support and relationship building, optimizing product adoption and enhancing patient c...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$92K - $138K *

Help us enhance clinical education by delivering expert training and support to healthcare professionals. Drive product adoption and optimize user competencies while fostering strong relationships wit...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$175K - $200K *

Drive impactful change in healthcare consulting by leveraging your expertise in clinical operations and research administration. Collaborate with executive leaders to solve complex challenges and fost...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$163K - $273K *

Shape the future of data intelligence by leading strategies that transform enterprise data into trusted analytics and AI capabilities, ensuring effective governance and cross-functional collaboration...

Reposted today

  •   11 - 15 years exp.  •   Finance & Insurance

$90K - $110K *

Transform your career by managing comprehensive Property Accounting and Finance operations across diverse portfolios, ensuring compliance and operational excellence while collaborating with key stakeh...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$86K - $155K *

Drive exceptional outcomes in clinical documentation by auditing inpatient records to ensure DRG compliance, identifying errors, and suggesting process improvements utilizing your coding expertise and...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$114K - $255K *

Join a team that's at the forefront of data privacy, providing legal guidance on compliance and risk management. Collaborate with stakeholders to implement privacy policies and respond to regulatory c...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $255K *

Shape the future of data privacy by delivering expert legal guidance on compliance, drafting critical documentation, and collaborating across teams to ensure business objectives align with regional re...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Empower the future of elder care by leading medical services, enhancing clinical quality, and fostering interdisciplinary collaboration to ensure exceptional participant outcomes and compliance within...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$139K - $218K *

Champion technology initiatives as a senior technical leader, guiding engineering technologies through their lifecycle. Drive effective adoption, enhance workflows, and influence strategy to improve p...

3 weeks ago

  •   15+ years exp.  •   Real Estate & Construction

$81K - $138K *

Transform user experiences by conducting in-depth UX research, synthesizing insights, and collaborating with cross-functional teams to enhance service design and product usability for federal clients...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$160K - $200K *

Unlock potential by leading managed care strategies across a complex health system. Drive payer negotiations, optimize contract performance, and enhance population health initiatives while collaborati...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$95K - $115K *

Drive innovative ServiceNow solutions in a dynamic, collaborative environment, ensuring effective development, integration, and deployment for government clients while enhancing platform capabilities...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Transform the learning landscape by leading the design and development of innovative educational materials. You'll engage diverse teams to create immersive, high-quality training experiences using cut...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$109K - $144K *

Lead the charge in optimizing Epic Population Health applications, ensuring effective support, administration, and collaboration with multi-disciplinary teams to enhance patient engagement and improve...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$86K - $118K *

Design and deliver engaging user experiences for medical benefits, leveraging user-centered principles and collaboration to enhance member satisfaction and streamline healthcare navigation. Shape impa...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $215K *

Unlock regional growth by leading a high-performing sales team, executing launch strategies, and fostering key customer relationships in a dynamic, fast-paced environment. Drive performance and ensure...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$121K - $161K *

Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$155K - $210K *

Drive success by championing patient needs and executing strategic account plans. Leverage clinical expertise and business acumen to exceed sales goals while fostering relationships with key stakehold...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team where you'll take ownership of key Corporate Performance Management projects, executing tasks from build to testing, while collaborating with clients and delivering high-quality wo...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $120K *

Shape the future of medical technology by launching innovative solutions and training healthcare teams. Drive customer satisfaction and sustainable practices while collaborating with surgical teams to...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$114K - $171K *

Shape the future of pharmaceutical care by overseeing safe medication practices, engaging with patients, and collaborating with healthcare teams to optimize therapy regimens and enhance patient outcom...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.