Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$160K - $200K *

Pioneer an innovative engineering culture by leading and scaling high-performing teams while integrating AI tools and practices to enhance delivery and impact aligned with organizational goals...

1 month ago

  •   8 - 10 years exp.  •   Energy & Utilities

$150K - $175K *

Lead the charge in delivering insights through advanced research and analysis, managing multiple projects, guiding team performance, and enhancing client relationships in the life sciences consulting...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$185K - $210K *

Lead and optimize global technology services across Adobe and Salesforce ecosystems. Drive strategic direction, client delivery, and team growth in a fast-paced environment. Champion technical excelle...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$93K - $120K *

Advance your career by providing innovative DBT therapy via live video to diverse clients. Collaborate with a supportive team, enhance skills through continual learning, and impact lives with evidence...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Transform business opportunities by driving pipeline growth and fostering relationships. Collaborate with sales teams to identify leads, engage prospects, and close deals, ensuring alignment with corp...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by driving business growth through lead generation, relationship building, and strategic engagement. Collaborate with sales teams to identify opportunities and close deals, ensuring a...

Raleigh, NCRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$45K - $250K *

Transform your career by connecting healthcare professionals with meaningful roles. Join a supportive team focused on building relationships and driving results while enjoying unlimited earning potent...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $400K *

Transform the Americas sales strategy by leading a diverse team to drive revenue through new business, renewals, and expansions. Focus on building repeatable processes while leveraging insights and ef...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Pioneer innovative AI solutions in healthcare, tackling ambiguous challenges directly. Collaborate with top experts, shipping impactful products at speed while taking full ownership of your work and d...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in developing interoperability specifications for Veteran health information exchange, collaborating with cross-functional teams to enhance standards and ensure compliance with federal...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$124K - $232K *

Empower your career with a pivotal role in developing innovative learning solutions for Global Operations, leveraging cutting-edge technologies and collaboration to enhance training effectiveness and...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion regulatory excellence by guiding product development teams, ensuring compliance with global standards, and fostering strong stakeholder relationships to drive business success...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Advance your career as a Telehealth Clinical Supervisor, providing leadership and clinical oversight to therapists delivering IOP-level care. Collaborate with a dedicated team to enhance patient outco...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$272K - $340K *

Elevate your career by leading CMC Regulatory strategy and execution. Drive submissions, build a high-performing team, and engage with global health authorities to ensure compliance and success in dru...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Pioneer a high-performing culture by partnering with leaders to deliver strategic HR solutions that enhance employee engagement, retention, and growth in a dynamic, mission-driven environment...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$500K+*

Champion innovative emergency radiology solutions while collaborating with a dedicated team. Enjoy flexible scheduling options and a supportive environment that prioritizes high-quality patient care a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $165K *

Join a dynamic team as a Managing Consultant, driving innovative solutions in Revenue Integrity. Oversee engagements, enhance client relationships, and lead project teams to optimize financial perform...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$500K+*

Join a team that's dedicated to delivering high-quality emergency radiology services. Enjoy flexible scheduling options, competitive compensation, and opportunities for career growth in a collaborativ...

Greensboro, NCRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform growth strategies for military decision-making by leading market initiatives, conducting research, and nurturing relationships with key stakeholders in the U.S. Navy and defense sectors to e...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$147K - $260K *

Design and govern Workday integration architecture, ensuring seamless finance data flow across platforms while collaborating with various architects to align with enterprise standards and maximize int...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$73K - $110K *

Champion patient care by utilizing the nursing process to assess, plan, and implement effective nursing strategies. Collaborate with a multidisciplinary team to enhance outcomes and uphold safety stan...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by collaborating with operators to build data integrations and onboarding systems, ensuring reliable analytics and faster go-lives. Join a dynamic team to shape innovative solutions i...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$80K - $95K *

Lead the design and execution of plumbing projects, ensuring compliance with standards and effective team coordination. Provide technical guidance and communicate project progress, addressing challeng...

1 month ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$148K - $263K *

Drive the design and implementation of AI-First operational environments, architecting resilient multi-cloud networks and building autonomous orchestration layers to enhance security and efficiency ac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Unlock your potential by driving sales of innovative pulmonary solutions. Collaborate with diverse stakeholders to enhance patient care and achieve sales targets in a dynamic healthcare environment. J...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.