Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$140K - $192K *

Join a team that's dedicated to driving demand in the Neurology Franchise. Collaborate with healthcare professionals and internal partners to achieve sales objectives while ensuring a patient-first ap...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower clinical development by collaborating with Medical Directors to ensure scientific integrity and data quality in clinical trials. Engage with experts, analyze data, and manage project deliverab...

North Carolina, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$154K - $196K *

Unlock potential by leading strategic government programs, managing P&L, and driving operational excellence. Oversee contract delivery, mentor staff, and foster client relationships to ensure growth a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Contribute to content strategy and development, ensuring clarity and compliance for advisor-facing materials. Collaborate with teams to enhance sales readiness and optimize content effectiveness acros...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Advance analytics and informatics solutions by integrating VA databases, developing dashboards, and collaborating in Agile teams to enhance healthcare delivery for Veterans, ensuring effective data ma...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Join a dynamic team as a subject-matter expert, providing strategic guidance and bespoke insurance solutions for complex multi-generational family offices, while influencing product development and en...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Elevate your career by leading enterprise Salesforce architecture strategy. Drive transformation across multi-cloud programs, ensuring scalable, secure solutions aligned with business goals while ment...

Today

  •   11 - 15 years exp.  •   Technical Services

$110K - $130K *

Drive high-impact BI solutions by shaping organizational data strategy, overseeing compliance, and ensuring innovation within the Patient Revenue Management Organization. Collaborate with leadership t...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$73K - $110K *

Join a team that's dedicated to providing exceptional ultrasound services. You'll assess, coordinate, and perform ultrasound exams while maintaining patient care standards and ensuring operational eff...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$166K - $200K *

Transform corporate growth through strategic M&A initiatives, mentoring talent, and fostering collaboration across teams. Drive industry relationships and manage due diligence to ensure alignment with...

Reposted 2 days ago

  •   11 - 15 years exp.  •   Healthcare

$175K - $210K *

Innovate in corporate development by leading M&A strategies, guiding teams, and fostering cross-functional collaboration to drive growth and align corporate objectives in a dynamic global environment...

Reposted 2 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Shape innovative programs to enhance patient access and affordability, collaborating with stakeholders to design solutions that drive patient care and project success. Lead the integration of operatio...

North Carolina, USRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$106K - $147K *

Drive proactive analysis of the cyber threat landscape, translating insights into actionable strategies for information security. Collaborate with teams to enhance preparedness and countermeasures, le...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Transform patient care by leading nursing services, ensuring compliance, and fostering a collaborative environment. Drive quality outcomes while managing staffing and performance in a dynamic healthca...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Help us ensure quality patient care by leading nursing services, overseeing compliance, and fostering a collaborative environment. Drive excellence in care delivery while managing staffing and perform...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Explore a fulfilling career in family medicine with a focus on outpatient care. Join a supportive team in a picturesque location, serving diverse patient needs while enjoying a balanced work-life and...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Empower health outcomes by providing exceptional family medicine care in a supportive rural environment. Join a collaborative team with a focus on patient-centered approaches, where you can thrive pro...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Join an established team of Urologists, providing comprehensive care with advanced technology. Enjoy a competitive compensation package and opportunities for teaching while practicing in a vibrant com...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $181K *

Drive the enterprise control framework for AI and emerging technologies, ensuring secure adoption and governance. Collaborate with cross-functional teams to enhance platform capabilities while managin...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $180K *

Join a team that's dedicated to developing scalable software solutions, designing responsive UIs, and optimizing backend services. Collaborate across functions to drive innovation and champion best pr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $118K *

Join a dedicated team in the Neurosurgery ICU, providing exceptional care to diverse patients. Utilize advanced nursing skills in a supportive environment, ensuring safety and therapeutic excellence w...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by building strong relationships with medical practices, driving growth, and enhancing patient access to psychiatric care. This field-based role requires dynamic engagement and strate...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Elevate your career by leading clinical operations in Hematology and Oncology across multiple sites. Collaborate with a dedicated team to enhance patient care, drive quality improvement, and foster ac...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Empower your career by providing comprehensive primary care to adults. Utilize advanced technology and preventive health strategies to enhance patient well-being while building lasting relationships i...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.