Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$100K - $120K *

Support clinical studies by assisting teams with tasks like medical monitoring and protocol management. Collaborate across functions and engage with stakeholders to ensure successful trial outcomes wh...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$78K - $84K *

Champion mental health initiatives by leading counseling services, supervising staff, and providing crisis intervention. Engage with the university community through outreach and consultation, ensurin...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$68K - $103K *

Reimagine critical care transport by providing expert patient care during transport. Collaborate with a dedicated team to ensure safety and efficiency while utilizing advanced medical procedures and t...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by leading the Radiation Therapy department to achieve clinical and operational excellence, ensuring compliance with healthcare standards while fostering professional growth and quali...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $100K *

Grow your career with a dynamic surgical unit, delivering exceptional patient care in a fast-paced environment. Collaborate with a dedicated team to enhance recovery for postoperative orthopedic and s...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Shape and execute innovative social media strategies to enhance brand storytelling, drive engagement, and support corporate communications initiatives while collaborating with diverse teams to achieve...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Pioneer a transformative approach to donation conversations, leading teams to enhance family engagement and authorization practices. Drive operational excellence while ensuring compassionate support f...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Transform the donation experience by leading strategic initiatives and high-performing teams dedicated to compassionate family engagement and operational excellence in organ and tissue donation proces...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$116K - $157K *

Grow your career with our FP&A Systems team, designing innovative EPM solutions and enhancing financial planning processes. Collaborate with various stakeholders to optimize efficiency and ensure data...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$145K - $175K *

Deliver innovative datacenter, cloud, and network solutions by leading architecture design, client engagement, and technical governance. Collaborate with cross-functional teams to shape complex infras...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$101K - $119K *

Unlock potential by driving strategic engagement marketing initiatives that enhance client and member interactions. Collaborate cross-functionally to develop effective communication strategies and mea...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that champions proactive advocacy within healthcare policy. Lead government affairs initiatives, engage with federal agencies, and strengthen strategic partnerships to ensure impactful rep...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Oversee and deliver exceptional diagnostic imaging services remotely, focusing on evening shifts. Collaborate within a dynamic team while managing varied inpatient and outpatient cases to support pati...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $185K *

Join a team that delivers comprehensive financial, estate, and tax planning to high-net-worth clients, providing expert guidance and fostering strong relationships to enhance client confidence and ret...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Unlock potential by leading AI transformation strategies that align technology solutions with business outcomes. Collaborate with C-suite and board members to develop and execute actionable roadmaps e...

United StatesRemote

Reposted 1 month ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Transform radiation therapy services through strategic leadership, optimizing clinical operations across multiple locations to enhance patient care quality, safety, and compliance while driving workfo...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join us to provide essential clinical support during surgical procedures, collaborating with surgeons and sales teams to optimize patient outcomes and enhance product usage. Your expertise will drive...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Unlock your potential by leading strategic initiatives that drive measurable business results. Collaborate with senior leaders to solve complex problems, evaluate opportunities, and translate strategy...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$121K - $240K *

Architect and evolve enterprise Salesforce architecture, driving scalable solutions aligned with commercial strategy, managing integration with Certinia, and leading AI inclusion for Sales, Marketing...

Durham, NCRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Unlock the potential of implementation science as a Senior Program Analyst, driving quality improvement and program evaluation initiatives. Manage processes, databases, and reporting to enhance projec...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Optimize client success by leading strategic relationships and enhancing revenue cycle performance. Drive measurable improvements, manage escalations, and ensure value realization across healthcare so...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $140K *

Engineer innovative health care delivery policies through quantitative analysis, leading projects that influence Medicare and Medicaid systems. Collaborate with multidisciplinary teams to evaluate and...

Durham, NCRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$130K - $155K *

Lead the charge in driving end-to-end strategy and discovery for complex client engagements. Collaborate with cross-functional teams to deliver actionable insights, build trusted relationships, and na...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $195K *

Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$210K - $250K *

Drive clinical excellence and lead strategic initiatives in House Calls and GUIDE programs, ensuring alignment with value-based care standards and operational goals while fostering a culture of collab...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.