Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$210K - $250K *

Join a team that's dedicated to delivering high-quality radiology services. You'll interpret a wide range of imaging exams, ensuring compliance and patient satisfaction while collaborating with health...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$88K - $98K *

Join a team that's shaping the future of paid social strategy for top consumer brands. Drive growth through innovative, data-driven campaigns on platforms like Meta, TikTok, and YouTube, while mentori...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Unlock potential by managing system functionality and usability, ensuring alignment between technical solutions and business needs. Collaborate on workflow management, documentation, and continuous im...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Accelerate program implementation and stakeholder engagement in pharmaceutical market access. Oversee daily operations, client relations, and staff management while ensuring adherence to budgets and p...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive the growth of the Higher Education Market Sector, collaborating with colleges and universities to deliver impactful campus planning and development projects. Lead multidisciplinary teams and fos...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$79K - $118K *

Contribute to exceptional patient care by providing skilled nursing across multiple units, adapting to diverse clinical environments while ensuring safety and quality standards are met. Collaborate wi...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform healthcare through innovative AI deployments. As a key technical expert, you'll develop and implement cutting-edge systems that enhance clinical workflows and optimize patient interactions...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to providing compassionate palliative care, delivering direct patient services, and collaborating with healthcare professionals to enhance patient comfort and quality of l...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Transform patient care by providing expert palliative services, collaborating with physicians to enhance treatment plans, and ensuring comprehensive symptom management for adults. Contribute to resear...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$105K - $129K *

Lead the charge in providing comprehensive care across independent, assisted, and skilled living environments. Manage outpatient practices, oversee clinical operations, and enhance resident well-being...

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join us to deliver comprehensive outpatient care, leveraging telehealth and in-person visits. Collaborate with a multidisciplinary team, enhancing patient outcomes for individuals facing psychiatric c...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$164K - $205K *

Lead the design and analysis of clinical validation studies, ensuring regulatory compliance and driving innovative research in molecular diagnostics. Collaborate with cross-functional teams to enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Champion global regulatory strategies by providing expert support from development to approval. Lead cross-functional teams and ensure compliance with US and international regulations while fostering...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$246K - $332K *

Transform the future of field operations by leading strategic initiatives that enhance commercial effectiveness and drive measurable impact across customer-facing teams. Collaborate with cross-functio...

RemoteRemote

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$191K - $293K *

Lead the charge in providing strategic employment law counsel, guiding the People team and stakeholders on compliance, investigations, and policy development to foster a supportive workplace while mit...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $185K *

Empower clients by leveraging deep ONESOURCE Direct Tax expertise to design innovative solutions using AI and automation tools. Engage directly with customers, manage projects, and drive efficiency wh...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$100K - $120K *

Elevate your career by leading financial planning and analysis, managing budgets, and driving strategic insights. Collaborate with cross-functional teams to enhance operational performance and deliver...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a collaborative technology architecture team to design scalable solutions, guide Agile development, and enhance application delivery while leveraging emerging technologies and cloud services...

Yesterday

  •   5 - 7 years exp.  •   Staffing

$225K - $275K *

Shape clinical excellence and drive strategic growth as a Medical Director, leading a dynamic veterinary team while maintaining an active caseload and fostering a collaborative environment in specialt...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $140K *

Join a team that's dedicated to transforming supply chain solutions through innovative Oracle OTM and GTM implementations, ensuring timely delivery and optimal client satisfaction while enhancing your...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Transportation

$110K - $125K *

Elevate healthcare operations by leading credentialing and medical staff services across multiple states. Drive compliance, streamline onboarding, and enhance workflows to support over 200 professiona...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join a team that's redefining litigation support through executive leadership, strategic direction, and expert testimony. Contribute to high-stakes engagements and mentor a talented team while driving...

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$103K - $242K *

Unlock transformative PLM solutions by leading strategic initiatives that enhance product development and drive innovation for top-tier manufacturing clients. Collaborate with experts to shape digital...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $95K *

Drive the successful adoption of advanced hearing solutions by providing expert clinical support and education to healthcare professionals. Collaborate closely with cross-functional teams to enhance p...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.